Ligand: T9N

Total number of chains: 3
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 4BCNC
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 4BCNA P24941 1 298 298.0 T9N:61299 Type1 Active DFGin 6.423 15.358 BLAminus -132.43, 173.08 59.42, 82.6 -96.18, 22.57 281.43, 68.76 -64.84, -22.05 in-in in 8.698 Saltbr-in 2.729 HRD-in -81.55, -53.36 72.5, 10.85 in-in-in SNCiii in-in ActLoopNT-in 2.934 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.04, 151.85 APE9-dihe-na 74.21, 127.37 APE8-dihe-in -54.17, 135.78 APE8-rot-in 301.89 APE67-dihe-in -57.52, -26.56 -44.55, -50.59 APE12-dist-in 13.181 APE11-dist-in 10.34 APE10-dist-in 7.243 APE9-dist-in 3.172 None TPO160 TPO160 XRAY 2.1 0.186 0.219 A 300 296 2 0 0 0 [[4, 286]] 1.0 4bcn CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4BCNC P24941 1 294 298.0 T9N:61296 Type1 Active DFGin 6.348 15.366 BLAminus -138.9, 178.12 52.91, 85.38 -99.92, 21.79 276.63, 71.1 -66.78, -15.26 in-in in 8.773 Saltbr-in 2.693 HRD-in -81.41, -55.77 72.05, 12.07 in-in-in SNCiii in-in ActLoopNT-in 2.954 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.57, 152.97 APE9-dihe-na 72.05, 129.38 APE8-dihe-in -57.95, 136.49 APE8-rot-in 299.74 APE67-dihe-in -57.16, -29.63 -40.31, -55.01 APE12-dist-in 13.049 APE11-dist-in 10.265 APE10-dist-in 7.088 APE9-dist-in 3.165 None TPO160 TPO160 XRAY 2.1 0.186 0.219 C 300 294 0 0 0 0 [[4, 286]] 1.0 4bcn CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK9 CDK9_HUMAN 4BCJA P50750 6 326 372.0 T9N:1327 Type1 Inactive DFGin 7.03 15.018 BLAminus -131.0, 170.86 63.37, 81.25 -96.53, 22.01 287.4, 63.38 -57.12, -37.16 in-out in 9.444 Saltbr-out 4.455 HRD-in -79.62, -45.57 66.85, 8.76 out-in-in SNCoii in-in ActLoopNT-in 2.873 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.55, 158.16 APE9-dihe-na 80.36, 134.65 APE8-dihe-in -47.14, 141.93 APE8-rot-in 299.93 APE67-dihe-in -67.12, -25.13 -50.6, -47.83 APE12-dist-in 13.096 APE11-dist-in 11.108 APE10-dist-in 6.84 APE9-dist-in 3.158 None TPO186 TPO186 XRAY 3.162 0.162 0.207 A 331 310 11 0 0 4 [[19, 315]] 1.0 4bcj CMGC_CDK9_HUMAN CMGC 4.1e-80 275.1 1 301 301 166 167 168 170 172 48 66 70 146 148 147 149 211 198 193 192 191 190 189 188 187 104 Cyclin-dependent kinase 9

Ligand: T9N

Total number of chains: 3
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 4BCNC
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 4BCNA P24941 1 298 298.0 T9N:61299 Type1 Active DFGin 6.423 15.358 BLAminus -132.43, 173.08 59.42, 82.6 -96.18, 22.57 281.43, 68.76 -64.84, -22.05 in-in in 8.698 Saltbr-in 2.729 HRD-in -81.55, -53.36 72.5, 10.85 in-in-in SNCiii in-in ActLoopNT-in 2.934 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.04, 151.85 APE9-dihe-na 74.21, 127.37 APE8-dihe-in -54.17, 135.78 APE8-rot-in 301.89 APE67-dihe-in -57.52, -26.56 -44.55, -50.59 APE12-dist-in 13.181 APE11-dist-in 10.34 APE10-dist-in 7.243 APE9-dist-in 3.172 None TPO160 TPO160 XRAY 2.1 0.186 0.219 A 300 296 2 0 0 0 [[4, 286]] 1.0 4bcn Homo sapiens CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4BCNC P24941 1 294 298.0 T9N:61296 Type1 Active DFGin 6.348 15.366 BLAminus -138.9, 178.12 52.91, 85.38 -99.92, 21.79 276.63, 71.1 -66.78, -15.26 in-in in 8.773 Saltbr-in 2.693 HRD-in -81.41, -55.77 72.05, 12.07 in-in-in SNCiii in-in ActLoopNT-in 2.954 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.57, 152.97 APE9-dihe-na 72.05, 129.38 APE8-dihe-in -57.95, 136.49 APE8-rot-in 299.74 APE67-dihe-in -57.16, -29.63 -40.31, -55.01 APE12-dist-in 13.049 APE11-dist-in 10.265 APE10-dist-in 7.088 APE9-dist-in 3.165 None TPO160 TPO160 XRAY 2.1 0.186 0.219 C 300 294 0 0 0 0 [[4, 286]] 1.0 4bcn Homo sapiens CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK9 CDK9_HUMAN 4BCJA P50750 6 326 372.0 T9N:1327 Type1 Inactive DFGin 7.03 15.018 BLAminus -131.0, 170.86 63.37, 81.25 -96.53, 22.01 287.4, 63.38 -57.12, -37.16 in-out in 9.444 Saltbr-out 4.455 HRD-in -79.62, -45.57 66.85, 8.76 out-in-in SNCoii in-in ActLoopNT-in 2.873 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.55, 158.16 APE9-dihe-na 80.36, 134.65 APE8-dihe-in -47.14, 141.93 APE8-rot-in 299.93 APE67-dihe-in -67.12, -25.13 -50.6, -47.83 APE12-dist-in 13.096 APE11-dist-in 11.108 APE10-dist-in 6.84 APE9-dist-in 3.158 None TPO186 TPO186 XRAY 3.162 0.162 0.207 A 331 310 11 0 0 4 [[19, 315]] 1.0 4bcj Homo sapiens CMGC_CDK9_HUMAN CMGC 4.1e-80 275.1 1 301 301 166 167 168 170 172 48 66 70 146 148 147 149 211 198 193 192 191 190 189 188 187 104 Cyclin-dependent kinase 9

Ligand: T9N

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name