Ligand: T5Y

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7CB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7CB Q04771 205 499 509.0 LU8:501,T5Y:505 Type1,Allosteric Inactive DFGin 7.0621 13.3895 BLAminus -126.3, 161.98 79.71, 89.61 -103.06, 23.5 302.55, 173.63 -67.99, -21.1 in-out in 8.8544 Saltbr-out 4.7577 HRD-in -77.43, -53.45 76.82, -0.13 out-in-out SNCoio in-out ActLoopNT-in 2.9125 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -119.01, 166.06 APE9-dihe-na -60.91, 165.47 APE8-dihe-in -62.27, 130.39 APE8-rot-in 299.14 APE67-dihe-in -63.71, -26.19 -64.69, -37.05 APE12-dist-in 10.3644 APE11-dist-out 6.2378 APE10-dist-out 8.9937 APE9-dist-in 3.938 Q207D None None XRAY 1.31 0.161 0.179 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s7c TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7CA Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508,T5Y:509,T5Y:510,T5Y:511 Type1,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3393 13.3454 BLAminus -122.66, 161.69 76.15, 92.72 -104.11, 24.78 300.15, 178.43 -66.33, -20.88 in-out in 9.2312 Saltbr-out 6.1549 HRD-in -76.23, -54.18 77.19, 0.83 out-in-out SNCoio in-out ActLoopNT-in 2.9506 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -124.75, 170.87 APE9-dihe-na -60.45, 165.58 APE8-dihe-in -64.98, 123.25 APE8-rot-in 303.45 APE67-dihe-in -56.7, -31.98 -63.36, -36.72 APE12-dist-none 999.0 APE11-dist-out 6.251 APE10-dist-out 8.8085 APE9-dist-in 3.7199 Q207D None None XRAY 1.31 0.161 0.179 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s7c TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: T5Y

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7CB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7CB Q04771 205 499 509.0 LU8:501,T5Y:505 Type1,Allosteric Inactive DFGin 7.0621 13.3895 BLAminus -126.3, 161.98 79.71, 89.61 -103.06, 23.5 302.55, 173.63 -67.99, -21.1 in-out in 8.8544 Saltbr-out 4.7577 HRD-in -77.43, -53.45 76.82, -0.13 out-in-out SNCoio in-out ActLoopNT-in 2.9125 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -119.01, 166.06 APE9-dihe-na -60.91, 165.47 APE8-dihe-in -62.27, 130.39 APE8-rot-in 299.14 APE67-dihe-in -63.71, -26.19 -64.69, -37.05 APE12-dist-in 10.3644 APE11-dist-out 6.2378 APE10-dist-out 8.9937 APE9-dist-in 3.938 Q207D None None XRAY 1.31 0.161 0.179 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s7c Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7CA Q04771 202 499 509.0 LU8:501,LU8:507,LU8:508,T5Y:509,T5Y:510,T5Y:511 Type1,Allosteric,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3393 13.3454 BLAminus -122.66, 161.69 76.15, 92.72 -104.11, 24.78 300.15, 178.43 -66.33, -20.88 in-out in 9.2312 Saltbr-out 6.1549 HRD-in -76.23, -54.18 77.19, 0.83 out-in-out SNCoio in-out ActLoopNT-in 2.9506 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -124.75, 170.87 APE9-dihe-na -60.45, 165.58 APE8-dihe-in -64.98, 123.25 APE8-rot-in 303.45 APE67-dihe-in -56.7, -31.98 -63.36, -36.72 APE12-dist-none 999.0 APE11-dist-out 6.251 APE10-dist-out 8.8085 APE9-dist-in 3.7199 Q207D None None XRAY 1.31 0.161 0.179 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s7c Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: T5Y

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name