Ligand: T5V

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7AB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7AB Q04771 205 499 509.0 LU8:501,T5V:505,T5V:506 Type1,Allosteric,Allosteric Inactive DFGin 7.0387 13.38 BLAminus -126.41, 163.07 76.94, 87.35 -100.8, 22.69 302.52, 175.53 -70.21, -15.13 in-out in 8.793 Saltbr-out 4.7212 HRD-in -77.59, -56.91 81.94, -2.79 out-in-out SNCoio in-out ActLoopNT-in 2.9306 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -121.27, 167.32 APE9-dihe-na -61.57, 164.52 APE8-dihe-in -61.32, 127.79 APE8-rot-in 299.15 APE67-dihe-in -59.77, -26.87 -62.23, -39.78 APE12-dist-in 10.3297 APE11-dist-out 6.2327 APE10-dist-out 8.9798 APE9-dist-in 3.8335 Q207D None None XRAY 1.3 0.16 0.18 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s7a TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7AA Q04771 201 499 509.0 LU8:501,LU8:507,LU8:508,T5V:509,T5V:510 Type1,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 8.342 13.3138 BLAminus -121.52, 160.72 75.85, 90.49 -101.87, 26.96 302.71, 179.1 -70.78, -16.97 in-out in 9.1949 Saltbr-out 6.1794 HRD-in -77.37, -53.71 77.98, -0.37 out-in-out SNCoio in-out ActLoopNT-in 2.9196 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -125.86, 170.85 APE9-dihe-na -58.96, 161.85 APE8-dihe-in -63.33, 122.4 APE8-rot-in 301.84 APE67-dihe-in -56.7, -33.07 -63.45, -35.84 APE12-dist-none 999.0 APE11-dist-out 6.3662 APE10-dist-out 8.8519 APE9-dist-in 3.6683 Q207D None None XRAY 1.3 0.16 0.18 A 301.0 285.0 14 32 20 12 [[207, 497]] 1.0 5s7a TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: T5V

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S7AB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S7AB Q04771 205 499 509.0 LU8:501,T5V:505,T5V:506 Type1,Allosteric,Allosteric Inactive DFGin 7.0387 13.38 BLAminus -126.41, 163.07 76.94, 87.35 -100.8, 22.69 302.52, 175.53 -70.21, -15.13 in-out in 8.793 Saltbr-out 4.7212 HRD-in -77.59, -56.91 81.94, -2.79 out-in-out SNCoio in-out ActLoopNT-in 2.9306 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -121.27, 167.32 APE9-dihe-na -61.57, 164.52 APE8-dihe-in -61.32, 127.79 APE8-rot-in 299.15 APE67-dihe-in -59.77, -26.87 -62.23, -39.78 APE12-dist-in 10.3297 APE11-dist-out 6.2327 APE10-dist-out 8.9798 APE9-dist-in 3.8335 Q207D None None XRAY 1.3 0.16 0.18 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s7a Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S7AA Q04771 201 499 509.0 LU8:501,LU8:507,LU8:508,T5V:509,T5V:510 Type1,Allosteric,Allosteric,Allosteric,Allosteric Inactive DFGin 8.342 13.3138 BLAminus -121.52, 160.72 75.85, 90.49 -101.87, 26.96 302.71, 179.1 -70.78, -16.97 in-out in 9.1949 Saltbr-out 6.1794 HRD-in -77.37, -53.71 77.98, -0.37 out-in-out SNCoio in-out ActLoopNT-in 2.9196 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -125.86, 170.85 APE9-dihe-na -58.96, 161.85 APE8-dihe-in -63.33, 122.4 APE8-rot-in 301.84 APE67-dihe-in -56.7, -33.07 -63.45, -35.84 APE12-dist-none 999.0 APE11-dist-out 6.3662 APE10-dist-out 8.8519 APE9-dist-in 3.6683 Q207D None None XRAY 1.3 0.16 0.18 A 301.0 285.0 14 32 20 12 [[207, 497]] 1.0 5s7a Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: T5V

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name