Ligand: SK8

Total number of chains: 3
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 66.7% 4LUDB
DFGin BLAminus 1 33.3% 4LL5A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK PIM1 PIM1_HUMAN 4LL5A P11309 34 305 313.0 SK8:401 Type1 Active DFGin 6.1536 14.9413 BLAminus -130.09, 167.4 64.64, 85.24 -96.78, 19.13 285.46, 79.08 -67.1, -17.77 in-in in 8.9048 Saltbr-in 2.9074 HRD-naA -72.89, -48.94 71.1, 5.66 in-in-in SNCiii in-in ActLoopNT-in 2.8583 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.97, 33.17 APE9-dihe-na -91.19, -159.67 APE8-dihe-in -86.75, 127.22 APE8-rot-in 309.08 APE67-dihe-in -69.44, -9.3 -64.52, -42.1 APE12-dist-in 9.5929 APE11-dist-in 8.6246 APE10-dist-in 5.5027 APE9-dist-in 3.7227 None None None XRAY 2.0 0.169 0.189 A 298.0 268.0 4 26 26 0 [[38, 290]] 1.0 4ll5 CAMK_PIM1_HUMAN CAMK 3.4e-65 225.9 1.0 256.0 256.0 185 186 187 189 191 67 89 93 164 166 165 167.0 224 211 206 205 204 203 202 201 200 121 Serine/threonine-protein kinase pim-1
TYR HCK HCK_HUMAN 4LUDA P08631 81 526 526.0 SK8:60603 Type1 Inactive DFGin 5.6892 15.9043 BLBplus -116.28, 150.35 49.81, 43.36 -87.12, 142.97 63.18, 99.69 99.14, -26.26 out-out out 13.412 Saltbr-out 13.2246 HRD-in -86.33, -45.0 75.85, -22.84 out-out-none SNCoon out-none ActLoopNT-out 7.3437 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 27.69 APE8-rot-na 31.21 APE67-dihe-in -65.55, -26.53 -70.89, -24.08 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 Q523E,Q524E,Q525I PTR522 PTR522 XRAY 2.85 0.215 0.261 A 454.0 421.0 20 29 16 13 [[262, 513]] 1.0 4lud TYR_HCK_HUMAN TYR 1.4e-95 325.6 1.0 260.0 260.0 398 399 400 402 404 290 305 309 378 380 379 381.0 439 427 422 421 420 419 418 417 416 334 Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 4LUDB P08631 81 524 526.0 SK8:60601 Type1 Inactive DFGin 4.7253 13.6615 BLBplus -114.11, 155.75 54.4, 45.03 -86.4, 134.52 55.73, 98.16 92.31, -27.22 out-out out 13.8813 Saltbr-out 14.0633 HRD-in -87.61, -43.81 76.82, -22.41 out-out-none SNCoon out-none ActLoopNT-out 7.3226 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 28.06 APE8-rot-na 31.21 APE67-dihe-in -64.0, -26.01 -70.38, -21.81 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 Q523E,Q524E,Q525I PTR522 PTR522 XRAY 2.85 0.215 0.261 B 454.0 409.0 15 29 16 13 [[262, 513]] 1.0 4lud TYR_HCK_HUMAN TYR 1.4e-95 325.6 1.0 260.0 260.0 398 399 400 402 404 290 305 309 378 380 379 381.0 439 427 422 421 420 419 418 417 416 334 Tyrosine-protein kinase HCK

Ligand: SK8

Total number of chains: 3
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 66.7% 4LUDB
DFGin BLAminus 1 33.3% 4LL5A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK PIM1 PIM1_HUMAN 4LL5A P11309 34 305 313.0 SK8:401 Type1 Active DFGin 6.1536 14.9413 BLAminus -130.09, 167.4 64.64, 85.24 -96.78, 19.13 285.46, 79.08 -67.1, -17.77 in-in in 8.9048 Saltbr-in 2.9074 HRD-naA -72.89, -48.94 71.1, 5.66 in-in-in SNCiii in-in ActLoopNT-in 2.8583 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.97, 33.17 APE9-dihe-na -91.19, -159.67 APE8-dihe-in -86.75, 127.22 APE8-rot-in 309.08 APE67-dihe-in -69.44, -9.3 -64.52, -42.1 APE12-dist-in 9.5929 APE11-dist-in 8.6246 APE10-dist-in 5.5027 APE9-dist-in 3.7227 None None None XRAY 2.0 0.169 0.189 A 298.0 268.0 4 26 26 0 [[38, 290]] 1.0 4ll5 Homo sapiens CAMK_PIM1_HUMAN CAMK 3.4e-65 225.9 1.0 256.0 256.0 185 186 187 189 191 67 89 93 164 166 165 167.0 224 211 206 205 204 203 202 201 200 121 Serine/threonine-protein kinase pim-1
TYR HCK HCK_HUMAN 4LUDA P08631 81 526 526.0 SK8:60603 Type1 Inactive DFGin 5.6892 15.9043 BLBplus -116.28, 150.35 49.81, 43.36 -87.12, 142.97 63.18, 99.69 99.14, -26.26 out-out out 13.412 Saltbr-out 13.2246 HRD-in -86.33, -45.0 75.85, -22.84 out-out-none SNCoon out-none ActLoopNT-out 7.3437 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 27.69 APE8-rot-na 31.21 APE67-dihe-in -65.55, -26.53 -70.89, -24.08 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 Q523E,Q524E,Q525I PTR522 PTR522 XRAY 2.85 0.215 0.261 A 454.0 421.0 20 29 16 13 [[262, 513]] 1.0 4lud Homo sapiens TYR_HCK_HUMAN TYR 1.4e-95 325.6 1.0 260.0 260.0 398 399 400 402 404 290 305 309 378 380 379 381.0 439 427 422 421 420 419 418 417 416 334 Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 4LUDB P08631 81 524 526.0 SK8:60601 Type1 Inactive DFGin 4.7253 13.6615 BLBplus -114.11, 155.75 54.4, 45.03 -86.4, 134.52 55.73, 98.16 92.31, -27.22 out-out out 13.8813 Saltbr-out 14.0633 HRD-in -87.61, -43.81 76.82, -22.41 out-out-none SNCoon out-none ActLoopNT-out 7.3226 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 28.06 APE8-rot-na 31.21 APE67-dihe-in -64.0, -26.01 -70.38, -21.81 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 Q523E,Q524E,Q525I PTR522 PTR522 XRAY 2.85 0.215 0.261 B 454.0 409.0 15 29 16 13 [[262, 513]] 1.0 4lud Homo sapiens TYR_HCK_HUMAN TYR 1.4e-95 325.6 1.0 260.0 260.0 398 399 400 402 404 290 305 309 378 380 379 381.0 439 427 422 421 420 419 418 417 416 334 Tyrosine-protein kinase HCK

Ligand: SK8

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name