Ligand: RFG

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7MU7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP3K5 M3K5_HUMAN 6VREA Q99683 671 940 1374.0 RFG:1002 Type1 Inactive DFGin 6.8152 13.6113 BLAminus -129.9, 174.85 60.66, 96.18 -107.07, 14.48 299.67, 100.35 -66.93, -27.63 in-in in 8.337 Saltbr-in 2.6983 HRD-in -75.62, -47.02 73.48, 5.8 in-in-out SNCiio in-out ActLoopNT-in 3.0816 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -116.85, 140.4 APE9-dihe-na -80.98, -165.5 APE8-dihe-in -71.42, 135.62 APE8-rot-in 312.64 APE67-dihe-in -74.41, -14.28 -63.87, -41.58 APE12-dist-in 10.791 APE11-dist-out 5.4295 APE10-dist-out 9.8756 APE9-dist-in 3.6996 None None None XRAY 2.29 0.19 0.24 A 291.0 261.0 9 28 21 7 [[678, 938]] 1.0 6vre STE_MAP3K5_HUMAN STE 1.2e-80 276.7 5.0 257.0 253.0 821 822 823 825 827 709 725 729 800 802 801 803.0 863 849 844 843 842 841 840 839 838 755 Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 6VREB Q99683 669 940 1374.0 RFG:1001 Type1 Inactive DFGin 6.4905 14.0124 BLAminus -129.48, 175.2 61.52, 95.42 -105.05, 19.46 294.04, 89.61 -65.54, -30.46 in-in in 8.7491 Saltbr-in 2.5759 HRD-in -76.83, -46.56 70.39, 7.92 in-in-out SNCiio in-out ActLoopNT-in 3.122 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoi APE10-dihe-na 999.0, 135.01 APE9-dihe-na -90.36, -169.74 APE8-dihe-in -80.73, 139.41 APE8-rot-out 88.48 APE67-dihe-in -72.31, -15.25 -63.35, -40.1 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 8.5562 APE9-dist-in 3.7094 None None None XRAY 2.29 0.19 0.24 B 291.0 260.0 12 28 20 8 [[678, 938]] 1.0 6vre STE_MAP3K5_HUMAN STE 1.2e-80 276.7 5.0 257.0 253.0 821 822 823 825 827 709 725 729 800 802 801 803.0 863 849 844 843 842 841 840 839 838 755 Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 7MU7A Q99683 671 940 1374.0 RFG:1003 Type1 Inactive DFGin 6.7566 13.7148 BLAminus -136.15, -179.86 56.07, 94.54 -107.99, 16.99 301.26, 96.73 -67.77, -29.01 in-in in 8.3813 Saltbr-in 2.6884 HRD-in -75.3, -47.48 74.9, 5.08 in-in-out SNCiio in-out ActLoopNT-in 3.0993 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -120.97, 138.28 APE9-dihe-na -81.33, -164.64 APE8-dihe-in -73.3, 130.4 APE8-rot-in 314.02 APE67-dihe-in -72.58, -18.66 -57.86, -41.71 APE12-dist-in 10.7633 APE11-dist-out 5.4213 APE10-dist-out 9.8862 APE9-dist-in 3.6601 None None None XRAY 2.298 0.207 0.242 A 334.0 263.0 7 28 21 7 [[678, 938]] 1.0 7mu7 STE_MAP3K5_HUMAN STE 1.9e-80 276.0 5.0 257.0 253.0 821 822 823 825 827 709 725 729 800 802 801 803.0 863 849 844 843 842 841 840 839 838 755 Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 7MU7B Q99683 669 940 1374.0 RFG:1003 Type1 Inactive DFGin 6.456 14.084 BLAminus -133.69, 179.33 55.17, 97.63 -107.16, 19.31 292.8, 94.2 -66.83, -32.31 in-in in 8.7143 Saltbr-in 2.699 HRD-in -75.96, -46.83 74.41, 6.4 in-in-out SNCiio in-out ActLoopNT-in 3.0979 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoi APE10-dihe-na 999.0, 134.07 APE9-dihe-na -87.4, -167.12 APE8-dihe-in -77.87, 130.78 APE8-rot-in 312.34 APE67-dihe-in -72.25, -17.64 -58.41, -40.62 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 8.4983 APE9-dist-in 3.5576 None None None XRAY 2.298 0.207 0.242 B 334.0 260.0 12 28 20 8 [[678, 938]] 1.0 7mu7 STE_MAP3K5_HUMAN STE 1.9e-80 276.0 5.0 257.0 253.0 821 822 823 825 827 709 725 729 800 802 801 803.0 863 849 844 843 842 841 840 839 838 755 Mitogen-activated protein kinase kinase kinase 5

Ligand: RFG

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7MU7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP3K5 M3K5_HUMAN 6VREA Q99683 671 940 1374.0 RFG:1002 Type1 Inactive DFGin 6.8152 13.6113 BLAminus -129.9, 174.85 60.66, 96.18 -107.07, 14.48 299.67, 100.35 -66.93, -27.63 in-in in 8.337 Saltbr-in 2.6983 HRD-in -75.62, -47.02 73.48, 5.8 in-in-out SNCiio in-out ActLoopNT-in 3.0816 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -116.85, 140.4 APE9-dihe-na -80.98, -165.5 APE8-dihe-in -71.42, 135.62 APE8-rot-in 312.64 APE67-dihe-in -74.41, -14.28 -63.87, -41.58 APE12-dist-in 10.791 APE11-dist-out 5.4295 APE10-dist-out 9.8756 APE9-dist-in 3.6996 None None None XRAY 2.29 0.19 0.24 A 291.0 261.0 9 28 21 7 [[678, 938]] 1.0 6vre Homo sapiens STE_MAP3K5_HUMAN STE 1.2e-80 276.7 5.0 257.0 253.0 821 822 823 825 827 709 725 729 800 802 801 803.0 863 849 844 843 842 841 840 839 838 755 Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 6VREB Q99683 669 940 1374.0 RFG:1001 Type1 Inactive DFGin 6.4905 14.0124 BLAminus -129.48, 175.2 61.52, 95.42 -105.05, 19.46 294.04, 89.61 -65.54, -30.46 in-in in 8.7491 Saltbr-in 2.5759 HRD-in -76.83, -46.56 70.39, 7.92 in-in-out SNCiio in-out ActLoopNT-in 3.122 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoi APE10-dihe-na 999.0, 135.01 APE9-dihe-na -90.36, -169.74 APE8-dihe-in -80.73, 139.41 APE8-rot-out 88.48 APE67-dihe-in -72.31, -15.25 -63.35, -40.1 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 8.5562 APE9-dist-in 3.7094 None None None XRAY 2.29 0.19 0.24 B 291.0 260.0 12 28 20 8 [[678, 938]] 1.0 6vre Homo sapiens STE_MAP3K5_HUMAN STE 1.2e-80 276.7 5.0 257.0 253.0 821 822 823 825 827 709 725 729 800 802 801 803.0 863 849 844 843 842 841 840 839 838 755 Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 7MU7A Q99683 671 940 1374.0 RFG:1003 Type1 Inactive DFGin 6.7566 13.7148 BLAminus -136.15, -179.86 56.07, 94.54 -107.99, 16.99 301.26, 96.73 -67.77, -29.01 in-in in 8.3813 Saltbr-in 2.6884 HRD-in -75.3, -47.48 74.9, 5.08 in-in-out SNCiio in-out ActLoopNT-in 3.0993 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -120.97, 138.28 APE9-dihe-na -81.33, -164.64 APE8-dihe-in -73.3, 130.4 APE8-rot-in 314.02 APE67-dihe-in -72.58, -18.66 -57.86, -41.71 APE12-dist-in 10.7633 APE11-dist-out 5.4213 APE10-dist-out 9.8862 APE9-dist-in 3.6601 None None None XRAY 2.298 0.207 0.242 A 334.0 263.0 7 28 21 7 [[678, 938]] 1.0 7mu7 Homo sapiens STE_MAP3K5_HUMAN STE 1.9e-80 276.0 5.0 257.0 253.0 821 822 823 825 827 709 725 729 800 802 801 803.0 863 849 844 843 842 841 840 839 838 755 Mitogen-activated protein kinase kinase kinase 5
STE MAP3K5 M3K5_HUMAN 7MU7B Q99683 669 940 1374.0 RFG:1003 Type1 Inactive DFGin 6.456 14.084 BLAminus -133.69, 179.33 55.17, 97.63 -107.16, 19.31 292.8, 94.2 -66.83, -32.31 in-in in 8.7143 Saltbr-in 2.699 HRD-in -75.96, -46.83 74.41, 6.4 in-in-out SNCiio in-out ActLoopNT-in 3.0979 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoi APE10-dihe-na 999.0, 134.07 APE9-dihe-na -87.4, -167.12 APE8-dihe-in -77.87, 130.78 APE8-rot-in 312.34 APE67-dihe-in -72.25, -17.64 -58.41, -40.62 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 8.4983 APE9-dist-in 3.5576 None None None XRAY 2.298 0.207 0.242 B 334.0 260.0 12 28 20 8 [[678, 938]] 1.0 7mu7 Homo sapiens STE_MAP3K5_HUMAN STE 1.9e-80 276.0 5.0 257.0 253.0 821 822 823 825 827 709 725 729 800 802 801 803.0 863 849 844 843 842 841 840 839 838 755 Mitogen-activated protein kinase kinase kinase 5

Ligand: RFG

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name