Ligand: R4S

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6VNYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR JAK1-2 JAK1_HUMAN 6W8LA 2.11 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R4S Type1 867 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1
TYR TYK2-2 TYK2_HUMAN 6VNYA 2.3 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai R4S Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2

Ligand: R4S

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6VNYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR JAK1-2 JAK1_HUMAN 6W8LA 2.11 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai R4S Type1 867 - 1154 0 PTR1034,PTR1035 None Tyrosine-protein kinase JAK1 Homo sapiens
TYR TYK2-2 TYK2_HUMAN 6VNYA 2.3 Inactive DFGin‑ABAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai R4S Type1 889 - 1178 0 PTR1054 C936A,Q969A,E971A,K972A,C1142A Non-receptor tyrosine-protein kinase TYK2 Homo sapiens

Ligand: R4S

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism