Ligand: QUE

Total number of chains: 6
Active chains: 2
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 100.0% 2O3PA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK DAPK1 DAPK1_HUMAN 5AUWA P53355 2 277 1430.0 QUE:400 Type1.5_Back Inactive DFGin 6.736 14.362 BLAminus -121.73, -178.06 59.14, 78.51 -94.31, 26.64 285.79, 75.1 -64.3, -24.9 in-out in 9.681 Saltbr-out 4.743 HRD-in -79.87, -48.06 71.62, 5.1 out-in-out SNCoio in-out ActLoopNT-in 2.914 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -159.58, 116.45 APE9-dihe-na -97.53, -146.04 APE8-dihe-in -82.59, 125.85 APE8-rot-in 299.77 APE67-dihe-in -60.64, -24.45 -47.47, -40.37 APE12-dist-in 9.912 APE11-dist-out 6.574 APE10-dist-out 9.248 APE9-dist-in 4.558 None None None XRAY 1.5 0.19 0.211 A 293 274 2 0 0 0 [[13, 275]] 1.0 5auw CAMK_DAPK1_HUMAN CAMK 6.1e-95 323.3 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 1
CAMK PIM1 PIM1_HUMAN 2O3PA P11309 33 306 313.0 QUE:501 Type1 Active DFGin 6.238 14.536 BLAminus -130.88, 170.78 53.54, 90.02 -97.28, 20.48 282.33, 78.83 -71.95, -12.75 in-in in 8.667 Saltbr-in 2.296 HRD-na-A -68.04, -46.2 63.08, 8.81 in-in-in SNCiii in-in ActLoopNT-in 2.858 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.42, 29.49 APE9-dihe-na -90.86, -153.23 APE8-dihe-in -86.96, 125.45 APE8-rot-in 306.17 APE67-dihe-in -64.91, -8.64 -61.09, -46.67 APE12-dist-in 9.661 APE11-dist-in 8.531 APE10-dist-in 5.429 APE9-dist-in 3.848 None None None XRAY 2.24 0.189 0.22 A 293 274 0 0 0 0 [[38, 290]] 1.0 2o3p CAMK_PIM1_HUMAN CAMK 3.2e-65 226.0 1 256 256 185 186 187 189 191 67 89 93 164 166 165 167 224 211 206 205 204 203 202 201 200 121 Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 4LMUA P11309 36 304 313.0 QUE:401 Type1 Active DFGin 6.162 14.431 BLAminus -125.85, 174.43 58.26, 85.32 -97.42, 18.39 285.76, 76.14 -68.38, -9.73 in-in in 8.702 Saltbr-in 2.385 HRD-na-A -71.42, -45.75 68.18, 3.07 in-in-in SNCiii in-in ActLoopNT-in 2.848 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.78, 30.35 APE9-dihe-na -86.53, -151.77 APE8-dihe-in -97.13, 122.66 APE8-rot-in 306.98 APE67-dihe-in -65.32, -7.73 -59.99, -46.55 APE12-dist-in 9.452 APE11-dist-in 8.617 APE10-dist-in 5.514 APE9-dist-in 3.834 None None None XRAY 2.38 0.172 0.204 A 298 265 4 0 0 0 [[38, 290]] 1.0 4lmu CAMK_PIM1_HUMAN CAMK 3.4e-65 225.9 1 256 256 185 186 187 189 191 67 89 93 164 166 165 167 224 211 206 205 204 203 202 201 200 121 Serine/threonine-protein kinase pim-1
CAMK STK17B ST17B_HUMAN 3LM5A O94768 25 301 372.0 QUE:60001 Type1.5_Back Inactive DFGin 6.205 14.402 BLAminus -129.37, -179.21 62.69, 64.02 -84.27, 20.32 288.75, 80.24 -59.93, -27.87 in-out in 9.775 Saltbr-out 5.748 HRD-in -61.79, -47.68 66.8, 10.86 out-in-out SNCoio in-out ActLoopNT-in 2.904 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 82.97 APE9-dihe-na -112.84, -148.46 APE8-dihe-in -67.19, 114.44 APE8-rot-in 309.07 APE67-dihe-in -58.89, -16.56 -51.09, -47.49 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 12.06 APE9-dist-out 7.597 None None None XRAY 2.29 0.204 0.281 A 327 267 10 0 0 9 [[32, 293]] 1.0 3lm5 CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
TYR HCK HCK_HUMAN 2HCKA P08631 79 526 526.0 QUE:60001 Type1 Inactive DFGin 6.883 12.565 BLAminus -135.76, 164.51 54.3, 68.19 -77.81, -69.05 321.97, 16.74 -94.78, 122.42 out-out out 13.211 Saltbr-out 14.338 HRD-out -102.03, 93.6 -54.25, 0.34 out-out-out SNCooo out-out ActLoopNT-out 11.489 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -143.26, 34.29 APE9-dihe-in -78.64, 135.24 APE8-dihe-out -35.07, 8.77 APE8-rot-na 20.27 APE67-dihe-in -59.37, -32.12 -13.52, -63.84 APE12-dist-na 12.256 APE11-dist-na 16.804 APE10-dist-na 16.196 APE9-dist-out 9.905 None PTR522 PTR522 XRAY 3.0 0.228 0.311 A 438 438 0 0 0 0 [[262, 513]] 1.0 2hck TYR_HCK_HUMAN TYR 1.4e-88 303.1 1 260 260 398 399 400 402 404 290 305 309 378 380 379 381 439 427 422 421 420 419 418 417 416 334 Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 2HCKB P08631 79 526 526.0 QUE:60532 Type1 Inactive DFGin 6.16 13.083 BLAminus -141.04, 165.96 51.23, 63.5 -82.56, -71.35 330.45, 4.54 -82.38, 116.43 out-out out 13.509 Saltbr-out 14.911 HRD-out -122.75, 94.61 -56.98, 8.3 out-out-out SNCooo out-out ActLoopNT-out 12.027 ActLoopCT-out TYR APEdihe_oioao APEdist_aaao APE10-dihe-out -128.02, 26.89 APE9-dihe-in -77.78, 149.77 APE8-dihe-out -49.68, 1.53 APE8-rot-na 15.16 APE67-dihe-out -63.87, -24.64 2.1, -68.98 APE12-dist-na 12.252 APE11-dist-na 17.305 APE10-dist-na 16.434 APE9-dist-out 10.222 None PTR522 PTR522 XRAY 3.0 0.228 0.311 B 438 438 0 0 0 0 [[262, 513]] 1.0 2hck TYR_HCK_HUMAN TYR 1.4e-88 303.1 1 260 260 398 399 400 402 404 290 305 309 378 380 379 381 439 427 422 421 420 419 418 417 416 334 Tyrosine-protein kinase HCK

Ligand: QUE

Total number of chains: 8
Active chains: 2
Total number of genes: 5
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 8 100.0% 2O3PA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK DAPK1 DAPK1_HUMAN 5AUWA P53355 2 277 1430.0 QUE:400 Type1.5_Back Inactive DFGin 6.736 14.362 BLAminus -121.73, -178.06 59.14, 78.51 -94.31, 26.64 285.79, 75.1 -64.3, -24.9 in-out in 9.681 Saltbr-out 4.743 HRD-in -79.87, -48.06 71.62, 5.1 out-in-out SNCoio in-out ActLoopNT-in 2.914 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -159.58, 116.45 APE9-dihe-na -97.53, -146.04 APE8-dihe-in -82.59, 125.85 APE8-rot-in 299.77 APE67-dihe-in -60.64, -24.45 -47.47, -40.37 APE12-dist-in 9.912 APE11-dist-out 6.574 APE10-dist-out 9.248 APE9-dist-in 4.558 None None None XRAY 1.5 0.19 0.211 A 293 274 2 0 0 0 [[13, 275]] 1.0 5auw Homo sapiens CAMK_DAPK1_HUMAN CAMK 6.1e-95 323.3 1 256 256 160 161 162 164 166 42 64 68 136 138 137 139 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 1
CAMK PIM1 PIM1_HUMAN 2O3PA P11309 33 306 313.0 QUE:501 Type1 Active DFGin 6.238 14.536 BLAminus -130.88, 170.78 53.54, 90.02 -97.28, 20.48 282.33, 78.83 -71.95, -12.75 in-in in 8.667 Saltbr-in 2.296 HRD-na-A -68.04, -46.2 63.08, 8.81 in-in-in SNCiii in-in ActLoopNT-in 2.858 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.42, 29.49 APE9-dihe-na -90.86, -153.23 APE8-dihe-in -86.96, 125.45 APE8-rot-in 306.17 APE67-dihe-in -64.91, -8.64 -61.09, -46.67 APE12-dist-in 9.661 APE11-dist-in 8.531 APE10-dist-in 5.429 APE9-dist-in 3.848 None None None XRAY 2.24 0.189 0.22 A 293 274 0 0 0 0 [[38, 290]] 1.0 2o3p Homo sapiens CAMK_PIM1_HUMAN CAMK 3.2e-65 226.0 1 256 256 185 186 187 189 191 67 89 93 164 166 165 167 224 211 206 205 204 203 202 201 200 121 Serine/threonine-protein kinase pim-1
CAMK PIM1 PIM1_HUMAN 4LMUA P11309 36 304 313.0 QUE:401 Type1 Active DFGin 6.162 14.431 BLAminus -125.85, 174.43 58.26, 85.32 -97.42, 18.39 285.76, 76.14 -68.38, -9.73 in-in in 8.702 Saltbr-in 2.385 HRD-na-A -71.42, -45.75 68.18, 3.07 in-in-in SNCiii in-in ActLoopNT-in 2.848 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.78, 30.35 APE9-dihe-na -86.53, -151.77 APE8-dihe-in -97.13, 122.66 APE8-rot-in 306.98 APE67-dihe-in -65.32, -7.73 -59.99, -46.55 APE12-dist-in 9.452 APE11-dist-in 8.617 APE10-dist-in 5.514 APE9-dist-in 3.834 None None None XRAY 2.38 0.172 0.204 A 298 265 4 0 0 0 [[38, 290]] 1.0 4lmu Homo sapiens CAMK_PIM1_HUMAN CAMK 3.4e-65 225.9 1 256 256 185 186 187 189 191 67 89 93 164 166 165 167 224 211 206 205 204 203 202 201 200 121 Serine/threonine-protein kinase pim-1
CAMK STK17B ST17B_HUMAN 3LM5A O94768 25 301 372.0 QUE:60001 Type1.5_Back Inactive DFGin 6.205 14.402 BLAminus -129.37, -179.21 62.69, 64.02 -84.27, 20.32 288.75, 80.24 -59.93, -27.87 in-out in 9.775 Saltbr-out 5.748 HRD-in -61.79, -47.68 66.8, 10.86 out-in-out SNCoio in-out ActLoopNT-in 2.904 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 82.97 APE9-dihe-na -112.84, -148.46 APE8-dihe-in -67.19, 114.44 APE8-rot-in 309.07 APE67-dihe-in -58.89, -16.56 -51.09, -47.49 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 12.06 APE9-dist-out 7.597 None None None XRAY 2.29 0.204 0.281 A 327 267 10 0 0 9 [[32, 293]] 1.0 3lm5 Homo sapiens CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
TYR HCK HCK_HUMAN 2HCKA P08631 79 526 526.0 QUE:60001 Type1 Inactive DFGin 6.883 12.565 BLAminus -135.76, 164.51 54.3, 68.19 -77.81, -69.05 321.97, 16.74 -94.78, 122.42 out-out out 13.211 Saltbr-out 14.338 HRD-out -102.03, 93.6 -54.25, 0.34 out-out-out SNCooo out-out ActLoopNT-out 11.489 ActLoopCT-out TYR APEdihe_oioai APEdist_aaao APE10-dihe-out -143.26, 34.29 APE9-dihe-in -78.64, 135.24 APE8-dihe-out -35.07, 8.77 APE8-rot-na 20.27 APE67-dihe-in -59.37, -32.12 -13.52, -63.84 APE12-dist-na 12.256 APE11-dist-na 16.804 APE10-dist-na 16.196 APE9-dist-out 9.905 None PTR522 PTR522 XRAY 3.0 0.228 0.311 A 438 438 0 0 0 0 [[262, 513]] 1.0 2hck Homo sapiens TYR_HCK_HUMAN TYR 1.4e-88 303.1 1 260 260 398 399 400 402 404 290 305 309 378 380 379 381 439 427 422 421 420 419 418 417 416 334 Tyrosine-protein kinase HCK
TYR HCK HCK_HUMAN 2HCKB P08631 79 526 526.0 QUE:60532 Type1 Inactive DFGin 6.16 13.083 BLAminus -141.04, 165.96 51.23, 63.5 -82.56, -71.35 330.45, 4.54 -82.38, 116.43 out-out out 13.509 Saltbr-out 14.911 HRD-out -122.75, 94.61 -56.98, 8.3 out-out-out SNCooo out-out ActLoopNT-out 12.027 ActLoopCT-out TYR APEdihe_oioao APEdist_aaao APE10-dihe-out -128.02, 26.89 APE9-dihe-in -77.78, 149.77 APE8-dihe-out -49.68, 1.53 APE8-rot-na 15.16 APE67-dihe-out -63.87, -24.64 2.1, -68.98 APE12-dist-na 12.252 APE11-dist-na 17.305 APE10-dist-na 16.434 APE9-dist-out 10.222 None PTR522 PTR522 XRAY 3.0 0.228 0.311 B 438 438 0 0 0 0 [[262, 513]] 1.0 2hck Homo sapiens TYR_HCK_HUMAN TYR 1.4e-88 303.1 1 260 260 398 399 400 402 404 290 305 309 378 380 379 381 439 427 422 421 420 419 418 417 416 334 Tyrosine-protein kinase HCK
OTHER IRE1 IRE1_YEAST 3LJ0A P32361 665 1115 1115.0 ADP:2101,QUE:1 ATPlike,Allosteric None DFGin 5.657 14.52 BLAminus -127.75, -159.8 55.73, 76.2 -100.97, 26.65 278.19, 55.54 -68.42, -38.12 in-in in 9.315 Saltbr-in 3.043 HRD-in -75.54, -40.03 69.65, -11.03 in-in-none SNCiin in-none ActLoopNT-in 2.884 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -61.99 APE8-rot-none 999.0 APE67-dihe-in -81.59, -8.09 -104.48, 18.72 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.217 0.224 A 434 407 20 0 0 7 [[672, 977]] 1.0 3lj0 Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 1e-35 129.7 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3LJ0B P32361 670 1115 1115.0 ADP:2101,QUE:1 ATPlike,Allosteric None DFGin 5.639 14.529 BLAminus -127.76, -160.17 56.44, 75.29 -99.49, 26.48 278.86, 54.86 -67.91, -37.63 in-in in 9.332 Saltbr-in 3.088 HRD-in -76.48, -40.82 70.18, -10.34 in-in-none SNCiin in-none ActLoopNT-in 2.864 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -62.45 APE8-rot-in 292.53 APE67-dihe-in -81.7, -8.3 -104.03, 18.85 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.217 0.224 B 434 402 20 0 0 7 [[672, 977]] 1.0 3lj0 Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 1e-35 129.7 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1

Ligand: QUE

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 3LJ0A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER IRE1 IRE1_YEAST 3LJ0A P32361 665 1115 1115.0 ADP:2101,QUE:1 ATPlike,Allosteric None DFGin 5.657 14.52 BLAminus -127.75, -159.8 55.73, 76.2 -100.97, 26.65 278.19, 55.54 -68.42, -38.12 in-in in 9.315 Saltbr-in 3.043 HRD-in -75.54, -40.03 69.65, -11.03 in-in-none SNCiin in-none ActLoopNT-in 2.884 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -61.99 APE8-rot-none 999.0 APE67-dihe-in -81.59, -8.09 -104.48, 18.72 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.217 0.224 A 434 407 20 0 0 7 [[672, 977]] 1.0 3lj0 Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 1e-35 129.7 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3LJ0B P32361 670 1115 1115.0 ADP:2101,QUE:1 ATPlike,Allosteric None DFGin 5.639 14.529 BLAminus -127.76, -160.17 56.44, 75.29 -99.49, 26.48 278.86, 54.86 -67.91, -37.63 in-in in 9.332 Saltbr-in 3.088 HRD-in -76.48, -40.82 70.18, -10.34 in-in-none SNCiin in-none ActLoopNT-in 2.864 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -62.45 APE8-rot-in 292.53 APE67-dihe-in -81.7, -8.3 -104.03, 18.85 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.217 0.224 B 434 402 20 0 0 7 [[672, 977]] 1.0 3lj0 Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 1e-35 129.7 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1