Ligand: Q8U

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 8BA3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-1 JAK2_HUMAN 8BA4A O60674 536 809 1132.0 Q8U:901 Type1 Pseudo DFGin 7.9438 13.4117 None -71.69, 172.79 -67.86, 161.07 -79.48, -19.97 29.54, 146.52 81.3, -166.68 in-na in 9.7879 Saltbr-na 999.0 HRD-in -74.34, -63.4 91.62, 2.89 na-out-out SNCaoo out-out ActLoopNT-out 8.5896 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -64.98, -39.28 APE9-dihe-out -56.91, -30.54 APE8-dihe-out -86.08, -1.03 APE8-rot-na 290.49 APE67-dihe-out -99.32, 21.83 -60.56, 137.6 APE12-dist-na 9.9255 APE11-dist-na 11.6473 APE10-dist-na 16.1443 APE9-dist-out 12.3271 W659A,W777A,F794H None None XRAY 2.1 0.219 0.274 A 289.0 274.0 0 24 24 0 [[545, 807], [849, 1125]] 2.0 8ba4 TYR_JAK2-1_HUMAN TYR 3.7e-64 222.5 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8BA3A O60674 536 812 1132.0 Q8U:60901 Type1 Pseudo DFGin 7.9449 13.7079 None -77.62, 172.89 -67.28, 156.81 -77.15, -9.78 24.71, 146.25 70.37, -168.01 out-na out 10.5812 Saltbr-na 999.0 HRD-in -73.02, -63.41 91.28, -5.41 na-out-out SNCaoo out-out ActLoopNT-out 8.8315 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -61.97, -37.88 APE9-dihe-out -69.87, -18.94 APE8-dihe-out -88.79, 5.92 APE8-rot-na 290.58 APE67-dihe-out -110.89, 28.54 -69.8, 129.69 APE12-dist-na 10.0415 APE11-dist-na 11.8896 APE10-dist-na 16.4253 APE9-dist-out 12.5092 W659A,W777A,F794H None None XRAY 1.4 0.175 0.197 A 289.0 277.0 0 24 24 0 [[545, 807], [849, 1125]] 2.0 8ba3 TYR_JAK2-1_HUMAN TYR 1.9e-64 223.4 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2

Ligand: Q8U

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 8BA3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-1 JAK2_HUMAN 8BA4A O60674 536 809 1132.0 Q8U:901 Type1 Pseudo DFGin 7.9438 13.4117 None -71.69, 172.79 -67.86, 161.07 -79.48, -19.97 29.54, 146.52 81.3, -166.68 in-na in 9.7879 Saltbr-na 999.0 HRD-in -74.34, -63.4 91.62, 2.89 na-out-out SNCaoo out-out ActLoopNT-out 8.5896 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -64.98, -39.28 APE9-dihe-out -56.91, -30.54 APE8-dihe-out -86.08, -1.03 APE8-rot-na 290.49 APE67-dihe-out -99.32, 21.83 -60.56, 137.6 APE12-dist-na 9.9255 APE11-dist-na 11.6473 APE10-dist-na 16.1443 APE9-dist-out 12.3271 W659A,W777A,F794H None None XRAY 2.1 0.219 0.274 A 289.0 274.0 0 24 24 0 [[545, 807], [849, 1125]] 2.0 8ba4 Homo sapiens TYR_JAK2-1_HUMAN TYR 3.7e-64 222.5 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8BA3A O60674 536 812 1132.0 Q8U:60901 Type1 Pseudo DFGin 7.9449 13.7079 None -77.62, 172.89 -67.28, 156.81 -77.15, -9.78 24.71, 146.25 70.37, -168.01 out-na out 10.5812 Saltbr-na 999.0 HRD-in -73.02, -63.41 91.28, -5.41 na-out-out SNCaoo out-out ActLoopNT-out 8.8315 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -61.97, -37.88 APE9-dihe-out -69.87, -18.94 APE8-dihe-out -88.79, 5.92 APE8-rot-na 290.58 APE67-dihe-out -110.89, 28.54 -69.8, 129.69 APE12-dist-na 10.0415 APE11-dist-na 11.8896 APE10-dist-na 16.4253 APE9-dist-out 12.5092 W659A,W777A,F794H None None XRAY 1.4 0.175 0.197 A 289.0 277.0 0 24 24 0 [[545, 807], [849, 1125]] 2.0 8ba3 Homo sapiens TYR_JAK2-1_HUMAN TYR 1.9e-64 223.4 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2

Ligand: Q8U

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name