| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | PTK2 | FAK1_HUMAN | 6YXVA | Q05397 | 414 | 686 | 1052.0 | Q2H:701 | Type1 | Inactive | DFGin | 6.7802 | 15.896 | None | -74.38, 172.96 | -50.5, 132.87 | -70.58, -33.64 | 295.92, 176.86 | -68.7, -41.79 | in-in | in | 7.5061 | Saltbr-in | 2.7399 | HRD-in | -63.96, -44.94 | 72.24, 2.92 | in-out-out | SNCioo | out-out | ActLoopNT-out | 11.9579 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 141.63 | APE8-dihe-in | -85.47, 62.62 | APE8-rot-na | 31.57 | APE67-dihe-in | -70.39, -3.07 | -47.35, -41.76 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.2994 | None | None | None | XRAY | 2.298 | 0.203 | 0.232 | A | 282.0 | 261.0 | 12 | 29 | 17 | 12 | [[422, 678]] | 1.0 | 6yxv | TYR_PTK2_HUMAN | TYR | 3.6e-93 | 317.6 | 1.0 | 260.0 | 260.0 | 563 | 564 | 565 | 567 | 569 | 454 | 471 | 475 | 543 | 545 | 544 | 546.0 | 604 | 592 | 587 | 586 | 585 | 584 | 583 | 582 | 581 | 500 | Focal adhesion kinase 1 |
| TYR | PTK2 | FAK1_HUMAN | 6YXVB | Q05397 | 415 | 686 | 1052.0 | Q2H:701 | Type1 | Inactive | DFGin | 6.7497 | 15.9158 | None | -75.08, 173.66 | -51.87, 131.63 | -68.87, -32.97 | 295.29, 177.69 | -68.78, -48.08 | in-in | in | 7.6569 | Saltbr-in | 2.7407 | HRD-in | -62.92, -46.64 | 75.37, -2.33 | in-out-out | SNCioo | out-out | ActLoopNT-out | 11.9776 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 142.82 | APE8-dihe-in | -86.78, 62.62 | APE8-rot-na | 30.42 | APE67-dihe-in | -70.82, -2.85 | -47.09, -41.03 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.187 | None | None | None | XRAY | 2.298 | 0.203 | 0.232 | B | 282.0 | 260.0 | 12 | 29 | 17 | 12 | [[422, 678]] | 1.0 | 6yxv | TYR_PTK2_HUMAN | TYR | 3.6e-93 | 317.6 | 1.0 | 260.0 | 260.0 | 563 | 564 | 565 | 567 | 569 | 454 | 471 | 475 | 543 | 545 | 544 | 546.0 | 604 | 592 | 587 | 586 | 585 | 584 | 583 | 582 | 581 | 500 | Focal adhesion kinase 1 |
| TYR | PTK2 | FAK1_HUMAN | 6YXVC | Q05397 | 414 | 686 | 1052.0 | Q2H:701 | Type1 | Inactive | DFGin | 6.8997 | 16.0318 | None | -74.5, 172.75 | -51.5, 132.3 | -71.72, -29.34 | 296.05, 175.78 | -71.46, -48.84 | in-in | in | 7.5013 | Saltbr-in | 2.7429 | HRD-in | -62.86, -46.42 | 73.82, -1.43 | in-out-out | SNCioo | out-out | ActLoopNT-out | 12.0766 | ActLoopCT-out | TYR | APEdihe_iiiai | APEdist_aaao | APE10-dihe-in | -77.88, 152.47 | APE9-dihe-in | -135.02, 147.01 | APE8-dihe-in | -86.57, 63.93 | APE8-rot-na | 30.34 | APE67-dihe-in | -70.64, -1.8 | -47.53, -42.32 | APE12-dist-na | 999.0 | APE11-dist-na | 16.304 | APE10-dist-na | 14.5361 | APE9-dist-out | 8.2347 | None | None | None | XRAY | 2.298 | 0.203 | 0.232 | C | 282.0 | 265.0 | 8 | 29 | 21 | 8 | [[422, 678]] | 1.0 | 6yxv | TYR_PTK2_HUMAN | TYR | 3.6e-93 | 317.6 | 1.0 | 260.0 | 260.0 | 563 | 564 | 565 | 567 | 569 | 454 | 471 | 475 | 543 | 545 | 544 | 546.0 | 604 | 592 | 587 | 586 | 585 | 584 | 583 | 582 | 581 | 500 | Focal adhesion kinase 1 |
| TYR | PTK2 | FAK1_HUMAN | 6YXVD | Q05397 | 415 | 686 | 1052.0 | Q2H:701 | Type1 | Inactive | DFGin | 6.5466 | 15.9097 | None | -69.88, 170.62 | -49.04, 129.98 | -64.73, -39.06 | 297.56, 170.69 | -61.08, -44.2 | in-in | in | 7.6236 | Saltbr-in | 2.7725 | HRD-in | -62.37, -45.76 | 74.99, -1.97 | in-none-out | SNCino | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 140.03 | APE8-dihe-in | -85.67, 62.63 | APE8-rot-na | 30.22 | APE67-dihe-in | -70.22, -2.35 | -46.36, -42.68 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.3226 | None | None | None | XRAY | 2.298 | 0.203 | 0.232 | D | 282.0 | 257.0 | 15 | 29 | 14 | 15 | [[422, 678]] | 1.0 | 6yxv | TYR_PTK2_HUMAN | TYR | 3.6e-93 | 317.6 | 1.0 | 260.0 | 260.0 | 563 | 564 | 565 | 567 | 569 | 454 | 471 | 475 | 543 | 545 | 544 | 546.0 | 604 | 592 | 587 | 586 | 585 | 584 | 583 | 582 | 581 | 500 | Focal adhesion kinase 1 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | PTK2 | FAK1_HUMAN | 6YXVA | Q05397 | 414 | 686 | 1052.0 | Q2H:701 | Type1 | Inactive | DFGin | 6.7802 | 15.896 | None | -74.38, 172.96 | -50.5, 132.87 | -70.58, -33.64 | 295.92, 176.86 | -68.7, -41.79 | in-in | in | 7.5061 | Saltbr-in | 2.7399 | HRD-in | -63.96, -44.94 | 72.24, 2.92 | in-out-out | SNCioo | out-out | ActLoopNT-out | 11.9579 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 141.63 | APE8-dihe-in | -85.47, 62.62 | APE8-rot-na | 31.57 | APE67-dihe-in | -70.39, -3.07 | -47.35, -41.76 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.2994 | None | None | None | XRAY | 2.298 | 0.203 | 0.232 | A | 282.0 | 261.0 | 12 | 29 | 17 | 12 | [[422, 678]] | 1.0 | 6yxv | Homo sapiens | TYR_PTK2_HUMAN | TYR | 3.6e-93 | 317.6 | 1.0 | 260.0 | 260.0 | 563 | 564 | 565 | 567 | 569 | 454 | 471 | 475 | 543 | 545 | 544 | 546.0 | 604 | 592 | 587 | 586 | 585 | 584 | 583 | 582 | 581 | 500 | Focal adhesion kinase 1 |
| TYR | PTK2 | FAK1_HUMAN | 6YXVB | Q05397 | 415 | 686 | 1052.0 | Q2H:701 | Type1 | Inactive | DFGin | 6.7497 | 15.9158 | None | -75.08, 173.66 | -51.87, 131.63 | -68.87, -32.97 | 295.29, 177.69 | -68.78, -48.08 | in-in | in | 7.6569 | Saltbr-in | 2.7407 | HRD-in | -62.92, -46.64 | 75.37, -2.33 | in-out-out | SNCioo | out-out | ActLoopNT-out | 11.9776 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 142.82 | APE8-dihe-in | -86.78, 62.62 | APE8-rot-na | 30.42 | APE67-dihe-in | -70.82, -2.85 | -47.09, -41.03 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.187 | None | None | None | XRAY | 2.298 | 0.203 | 0.232 | B | 282.0 | 260.0 | 12 | 29 | 17 | 12 | [[422, 678]] | 1.0 | 6yxv | Homo sapiens | TYR_PTK2_HUMAN | TYR | 3.6e-93 | 317.6 | 1.0 | 260.0 | 260.0 | 563 | 564 | 565 | 567 | 569 | 454 | 471 | 475 | 543 | 545 | 544 | 546.0 | 604 | 592 | 587 | 586 | 585 | 584 | 583 | 582 | 581 | 500 | Focal adhesion kinase 1 |
| TYR | PTK2 | FAK1_HUMAN | 6YXVC | Q05397 | 414 | 686 | 1052.0 | Q2H:701 | Type1 | Inactive | DFGin | 6.8997 | 16.0318 | None | -74.5, 172.75 | -51.5, 132.3 | -71.72, -29.34 | 296.05, 175.78 | -71.46, -48.84 | in-in | in | 7.5013 | Saltbr-in | 2.7429 | HRD-in | -62.86, -46.42 | 73.82, -1.43 | in-out-out | SNCioo | out-out | ActLoopNT-out | 12.0766 | ActLoopCT-out | TYR | APEdihe_iiiai | APEdist_aaao | APE10-dihe-in | -77.88, 152.47 | APE9-dihe-in | -135.02, 147.01 | APE8-dihe-in | -86.57, 63.93 | APE8-rot-na | 30.34 | APE67-dihe-in | -70.64, -1.8 | -47.53, -42.32 | APE12-dist-na | 999.0 | APE11-dist-na | 16.304 | APE10-dist-na | 14.5361 | APE9-dist-out | 8.2347 | None | None | None | XRAY | 2.298 | 0.203 | 0.232 | C | 282.0 | 265.0 | 8 | 29 | 21 | 8 | [[422, 678]] | 1.0 | 6yxv | Homo sapiens | TYR_PTK2_HUMAN | TYR | 3.6e-93 | 317.6 | 1.0 | 260.0 | 260.0 | 563 | 564 | 565 | 567 | 569 | 454 | 471 | 475 | 543 | 545 | 544 | 546.0 | 604 | 592 | 587 | 586 | 585 | 584 | 583 | 582 | 581 | 500 | Focal adhesion kinase 1 |
| TYR | PTK2 | FAK1_HUMAN | 6YXVD | Q05397 | 415 | 686 | 1052.0 | Q2H:701 | Type1 | Inactive | DFGin | 6.5466 | 15.9097 | None | -69.88, 170.62 | -49.04, 129.98 | -64.73, -39.06 | 297.56, 170.69 | -61.08, -44.2 | in-in | in | 7.6236 | Saltbr-in | 2.7725 | HRD-in | -62.37, -45.76 | 74.99, -1.97 | in-none-out | SNCino | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 140.03 | APE8-dihe-in | -85.67, 62.63 | APE8-rot-na | 30.22 | APE67-dihe-in | -70.22, -2.35 | -46.36, -42.68 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.3226 | None | None | None | XRAY | 2.298 | 0.203 | 0.232 | D | 282.0 | 257.0 | 15 | 29 | 14 | 15 | [[422, 678]] | 1.0 | 6yxv | Homo sapiens | TYR_PTK2_HUMAN | TYR | 3.6e-93 | 317.6 | 1.0 | 260.0 | 260.0 | 563 | 564 | 565 | 567 | 569 | 454 | 471 | 475 | 543 | 545 | 544 | 546.0 | 604 | 592 | 587 | 586 | 585 | 584 | 583 | 582 | 581 | 500 | Focal adhesion kinase 1 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|