KinCore

Ligand: PY1

Total number of chains: 1

Active chains: 0

Total number of genes: 1

Spatial label	Dihedral label	Number of Chains	Percent	Representative
DFGin	BLAminus	1	100.0%	1PY5A

Download database table as tsv Basic page

Hover over column headers for tooltip help

Group	Gene	SwissprotID	PDB	UniprotID	First_obs_res	Last_obs_res	Length_Unp	Ligand	Ligand_type	Activity_label	Spatial_label	Phe_Glu4_dis	Phe_Lys_dis	Dihedral_label	XDFG φ,ψ	DFG-Asp φ,ψ	DFG-Phe φ,ψ	DFG-Phe χ1,χ2	DFG-Gly φ,ψ	ChelixSaltbr_label	Chelix_label	Lys_Glu_dis	Saltbr_label	LysNZ_GluOE_dis	HRD_label	His φ,ψ	Arg φ,ψ	SNC_label	SNCpymol_label	ActLoop_label	ActLoopNT_label	DFG6_XHRD_dis	ActLoopCT_label	APEtype	APEdihe_label	APEdist_label	APE10_dihe_label	APE10 φ,ψ	APE9_dihe_label	APE9 φ,ψ	APE8_dihe_label	APE8 φ,ψ	APE8_rotamer_label	APE8 χ1	APE67_label	APE6 φ,ψ	APE7 φ,ψ	APE12_dist_label	APE12_DFG4_dis	APE11_dist_label	APE11_DFG4_dis	APE10_dist_label	APE10_DFG4_dis	APE9_dist_label	APE9_Arg_dis	Chain_mut	Chain_phos	Modified_aa	Method	Resolution	Rvalue	FreeRvalue	Chain_id	ChainLen	Ordered_residues	DomainBreak	ActLoopLength	ActLoopResolvedResidues	ActLoopDisorderedResidues	Kinase_domains_Unp	N_Kinase_domains_Unp	pdb	Kincore_name	hmm	Evalue	Score	hmmbeg	hmmend	hmmlen	XDFGnum	DFGnum	PHEnum	DFG4num	DFG6num	LYSnum	GLUnum	GLU4num	XHRDnum	ARGnum	HRDnum	HRDaspnum	aFaspnum	APEnum	APE6num	APE7num	APE8num	APE9num	APE10num	APE11num	APE12num	Hinge1num	Protein_name
TKL	TGFBR1	TGFR1_HUMAN	1PY5A	P36897	200	500	503.0	PY1:700	Type1	Inactive	DFGin	6.325	13.096	BLAminus	-139.22, -176.23	51.49, 62.68	-91.32, 17.81	306.9, 168.43	-57.65, -31.73	in-in	in	7.831	Saltbr-in	2.897	HRD-in	-74.07, -48.58	75.5, -7.56	in-in-out	SNCiio	in-out	ActLoopNT-in	2.862	ActLoopCT-out	nonTYR	APEdihe_aaiii	APEdist_iioi	APE10-dihe-na	-82.55, -147.04	APE9-dihe-na	-97.21, -166.02	APE8-dihe-in	-77.65, 124.21	APE8-rot-in	307.07	APE67-dihe-in	-64.31, -27.94	-63.63, -30.26	APE12-dist-in	11.444	APE11-dist-in	8.66	APE10-dist-out	8.572	APE9-dist-in	4.119	None	None	None	XRAY	2.3	0.26	0.292	A	326	301	0	0	0	0	[[205, 494]]	1.0	1py5	TKL_TGFBR1_HUMAN	TKL	4.1e-85	291.4	3	266	264	350	351	352	354	356	232	245	249	330	332	331	333	400	382	377	376	375	374	373	372	371	281	TGF-beta receptor type-1

Ligand: PY1

Total number of chains: 2

Active chains: 1

Total number of genes: 2

Spatial label	Dihedral label	Number of Chains	Percent	Representative
DFGin	BLAminus	2	100.0%	9NZKA

Download database table as tsv Basic page

Hover over column headers for tooltip help

Group	Gene	SwissprotID	PDB	UniprotID	First_obs_res	Last_obs_res	Length_Unp	Ligand	Ligand_type	Activity_label	Spatial_label	Phe_Glu4_dis	Phe_Lys_dis	Dihedral_label	XDFG φ,ψ	DFG-Asp φ,ψ	DFG-Phe φ,ψ	DFG-Phe χ1,χ2	DFG-Gly φ,ψ	ChelixSaltbr_label	Chelix_label	Lys_Glu_dis	Saltbr_label	LysNZ_GluOE_dis	HRD_label	His φ,ψ	Arg φ,ψ	SNC_label	SNCpymol_label	ActLoop_label	ActLoopNT_label	DFG6_XHRD_dis	ActLoopCT_label	APEtype	APEdihe_label	APEdist_label	APE10_dihe_label	APE10 φ,ψ	APE9_dihe_label	APE9 φ,ψ	APE8_dihe_label	APE8 φ,ψ	APE8_rotamer_label	APE8 χ1	APE67_label	APE6 φ,ψ	APE7 φ,ψ	APE12_dist_label	APE12_DFG4_dis	APE11_dist_label	APE11_DFG4_dis	APE10_dist_label	APE10_DFG4_dis	APE9_dist_label	APE9_Arg_dis	Chain_mut	Chain_phos	Modified_aa	Method	Resolution	Rvalue	FreeRvalue	Chain_id	ChainLen	Ordered_residues	DomainBreak	ActLoopLength	ActLoopResolvedResidues	ActLoopDisorderedResidues	Kinase_domains_Unp	N_Kinase_domains_Unp	pdb	Species	Kincore_name	hmm	Evalue	Score	hmmbeg	hmmend	hmmlen	XDFGnum	DFGnum	PHEnum	DFG4num	DFG6num	LYSnum	GLUnum	GLU4num	XHRDnum	ARGnum	HRDnum	HRDaspnum	aFaspnum	APEnum	APE6num	APE7num	APE8num	APE9num	APE10num	APE11num	APE12num	Hinge1num	Protein_name
CK1	YCK2	A0A8H6C375_CANAX	9NZKA	A0A8H6C375	37	342	491.0	PY1:401	Type1	Active	DFGin	6.667	14.632	BLAminus	-123.53, -176.7	59.46, 85.99	-101.23, 22.92	290.97, 94.84	-64.24, -26.89	in-in	in	7.982	Saltbr-in	3.032	HRD-in	-91.37, -46.29	68.89, 4.68	in-in-in	SNCiii	in-in	ActLoopNT-in	2.774	ActLoopCT-in	nonTYR	APEdihe_aaiii	APEdist_iiii	APE10-dihe-na	-74.37, 131.27	APE9-dihe-na	144.44, -170.54	APE8-dihe-in	-103.59, 123.01	APE8-rot-in	303.79	APE67-dihe-in	-60.54, -33.91	-64.0, -33.14	APE12-dist-in	11.669	APE11-dist-in	13.317	APE10-dist-in	7.536	APE9-dist-in	4.521	None	None	None	XRAY	1.7	0.176	0.211	A	309	306	0	0	0	0	[[44, 312]]	1.0	9nzk	Candida albicans	CK1_YCK2_CANAX	CK1	4.4e-95	324.0	1	260	260	185	186	187	189	191	73	87	91	160	162	161	163	232	220	215	214	213	212	211	210	209	118	non-specific serine/threonine protein kinase
TKL	TGFBR1	TGFR1_HUMAN	1PY5A	P36897	200	500	503.0	PY1:700	Type1	Inactive	DFGin	6.325	13.096	BLAminus	-139.22, -176.23	51.49, 62.68	-91.32, 17.81	306.9, 168.43	-57.65, -31.73	in-in	in	7.831	Saltbr-in	2.897	HRD-in	-74.07, -48.58	75.5, -7.56	in-in-out	SNCiio	in-out	ActLoopNT-in	2.862	ActLoopCT-out	nonTYR	APEdihe_aaiii	APEdist_iioi	APE10-dihe-na	-82.55, -147.04	APE9-dihe-na	-97.21, -166.02	APE8-dihe-in	-77.65, 124.21	APE8-rot-in	307.07	APE67-dihe-in	-64.31, -27.94	-63.63, -30.26	APE12-dist-in	11.444	APE11-dist-in	8.66	APE10-dist-out	8.572	APE9-dist-in	4.119	None	None	None	XRAY	2.3	0.26	0.292	A	326	301	0	0	0	0	[[205, 494]]	1.0	1py5	Homo sapiens	TKL_TGFBR1_HUMAN	TKL	4.1e-85	291.4	3	266	264	350	351	352	354	356	232	245	249	330	332	331	333	400	382	377	376	375	374	373	372	371	281	TGF-beta receptor type-1

Ligand: PY1

Total number of chains: 1

Active chains: 1

Total number of genes: 1

Spatial label	Dihedral label	Number of Chains	Percent	Representative
DFGin	BLAminus	1	100.0%	9NZKA

Download database table as tsv Basic page

Hover over column headers for tooltip help

Group	Gene	SwissprotID	PDB	UniprotID	First_obs_res	Last_obs_res	Length_Unp	Ligand	Ligand_type	Activity_label	Spatial_label	Phe_Glu4_dis	Phe_Lys_dis	Dihedral_label	XDFG φ,ψ	DFG-Asp φ,ψ	DFG-Phe φ,ψ	DFG-Phe χ1,χ2	DFG-Gly φ,ψ	ChelixSaltbr_label	Chelix_label	Lys_Glu_dis	Saltbr_label	LysNZ_GluOE_dis	HRD_label	His φ,ψ	Arg φ,ψ	SNC_label	SNCpymol_label	ActLoop_label	ActLoopNT_label	DFG6_XHRD_dis	ActLoopCT_label	APEtype	APEdihe_label	APEdist_label	APE10_dihe_label	APE10 φ,ψ	APE9_dihe_label	APE9 φ,ψ	APE8_dihe_label	APE8 φ,ψ	APE8_rotamer_label	APE8 χ1	APE67_label	APE6 φ,ψ	APE7 φ,ψ	APE12_dist_label	APE12_DFG4_dis	APE11_dist_label	APE11_DFG4_dis	APE10_dist_label	APE10_DFG4_dis	APE9_dist_label	APE9_Arg_dis	Chain_mut	Chain_phos	Modified_aa	Method	Resolution	Rvalue	FreeRvalue	Chain_id	ChainLen	Ordered_residues	DomainBreak	ActLoopLength	ActLoopResolvedResidues	ActLoopDisorderedResidues	Kinase_domains_Unp	N_Kinase_domains_Unp	pdb	Species	Kincore_name	hmm	Evalue	Score	hmmbeg	hmmend	hmmlen	XDFGnum	DFGnum	PHEnum	DFG4num	DFG6num	LYSnum	GLUnum	GLU4num	XHRDnum	ARGnum	HRDnum	HRDaspnum	aFaspnum	APEnum	APE6num	APE7num	APE8num	APE9num	APE10num	APE11num	APE12num	Hinge1num	Protein_name
CK1	YCK2	A0A8H6C375_CANAX	9NZKA	A0A8H6C375	37	342	491.0	PY1:401	Type1	Active	DFGin	6.667	14.632	BLAminus	-123.53, -176.7	59.46, 85.99	-101.23, 22.92	290.97, 94.84	-64.24, -26.89	in-in	in	7.982	Saltbr-in	3.032	HRD-in	-91.37, -46.29	68.89, 4.68	in-in-in	SNCiii	in-in	ActLoopNT-in	2.774	ActLoopCT-in	nonTYR	APEdihe_aaiii	APEdist_iiii	APE10-dihe-na	-74.37, 131.27	APE9-dihe-na	144.44, -170.54	APE8-dihe-in	-103.59, 123.01	APE8-rot-in	303.79	APE67-dihe-in	-60.54, -33.91	-64.0, -33.14	APE12-dist-in	11.669	APE11-dist-in	13.317	APE10-dist-in	7.536	APE9-dist-in	4.521	None	None	None	XRAY	1.7	0.176	0.211	A	309	306	0	0	0	0	[[44, 312]]	1.0	9nzk	Candida albicans	CK1_YCK2_CANAX	CK1	4.4e-95	324.0	1	260	260	185	186	187	189	191	73	87	91	160	162	161	163	232	220	215	214	213	212	211	210	209	118	non-specific serine/threonine protein kinase