Ligand: PE8

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 8YHWD
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP3K14 M3K14_HUMAN 8YHWD Q99558 334 675 947.0 AGS:701,PE8:703 ATPlike,Allosteric Inactive DFGin 5.207 13.52 BLAminus -132.04, 179.74 71.06, 78.01 -98.25, 28.04 291.93, 89.49 -68.38, -20.37 in-in in 8.711 Saltbr-in 2.795 HRD-in -71.1, -54.2 99.37, -12.6 in-in-out SNCiio in-out ActLoopNT-in 3.076 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -75.74, 155.59 APE9-dihe-na -80.11, -42.03 APE8-dihe-in -135.61, 130.31 APE8-rot-in 298.0 APE67-dihe-in -60.15, -27.6 -63.0, -48.69 APE12-dist-in 7.886 APE11-dist-out 7.088 APE10-dist-in 7.992 APE9-dist-in 3.95 None None None XRAY 2.9 0.196 0.241 D 351 329 13 0 0 13 [[399, 652]] 1.0 8yhw STE_MAP3K14_HUMAN STE 1.1e-62 217.7 4 252 249 533 534 535 537 539 429 440 444 512 514 513 515 578 566 561 560 559 558 557 556 555 470 Mitogen-activated protein kinase kinase kinase 14

Ligand: PE8

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 8YHWD
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP3K14 M3K14_HUMAN 8YHWD Q99558 334 675 947.0 AGS:701,PE8:703 ATPlike,Allosteric Inactive DFGin 5.207 13.52 BLAminus -132.04, 179.74 71.06, 78.01 -98.25, 28.04 291.93, 89.49 -68.38, -20.37 in-in in 8.711 Saltbr-in 2.795 HRD-in -71.1, -54.2 99.37, -12.6 in-in-out SNCiio in-out ActLoopNT-in 3.076 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -75.74, 155.59 APE9-dihe-na -80.11, -42.03 APE8-dihe-in -135.61, 130.31 APE8-rot-in 298.0 APE67-dihe-in -60.15, -27.6 -63.0, -48.69 APE12-dist-in 7.886 APE11-dist-out 7.088 APE10-dist-in 7.992 APE9-dist-in 3.95 None None None XRAY 2.9 0.196 0.241 D 351 329 13 0 0 13 [[399, 652]] 1.0 8yhw Homo sapiens STE_MAP3K14_HUMAN STE 1.1e-62 217.7 4 252 249 533 534 535 537 539 429 440 444 512 514 513 515 578 566 561 560 559 558 557 556 555 470 Mitogen-activated protein kinase kinase kinase 14

Ligand: PE8

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name