Ligand: PDR

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 75.0% 3LVPB
DFGin BLAminus 1 25.0% 3LVPD
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR IGF1R IGF1R_HUMAN 3LVPA P08069 989 1286 1367.0 PDR:1 Type1 Inactive DFGin 6.0566 14.1894 ABAminus -121.12, 43.14 -157.44, 127.28 -132.71, 38.65 304.97, 81.73 -58.62, -41.18 in-out in 9.1128 Saltbr-out 6.2341 HRD-in -83.6, -34.91 64.8, -16.89 out-in-in SNCoii in-in ActLoopNT-in 3.2098 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -64.15, 163.21 APE9-dihe-in -98.5, 148.37 APE8-dihe-in -75.76, 55.82 APE8-rot-na 35.7 APE67-dihe-in -60.82, -13.12 -37.4, -57.84 APE12-dist-na 11.8103 APE11-dist-na 10.8587 APE10-dist-na 12.5547 APE9-dist-in 7.7687 None None None XRAY 3.0 0.226 0.279 A 336.0 289.0 9 30 23 7 [[999, 1268]] 1.0 3lvp TYR_IGF1R_HUMAN TYR 2.6e-95 324.6 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LVPB P08069 986 1285 1367.0 PDR:2 Type1 Inactive DFGin 5.9292 13.6583 ABAminus -100.72, -41.98 -105.19, 149.94 -137.93, 21.74 308.71, 87.7 -51.11, -10.36 in-out in 9.3758 Saltbr-out 4.6992 HRD-in -75.05, -36.77 62.12, -0.15 out-in-in SNCoii in-in ActLoopNT-in 2.8014 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -133.19, 147.36 APE9-dihe-in -73.98, 133.27 APE8-dihe-in -70.94, 67.87 APE8-rot-na 28.67 APE67-dihe-in -66.44, 0.67 -51.66, -49.49 APE12-dist-na 12.7663 APE11-dist-na 10.8475 APE10-dist-na 12.4429 APE9-dist-in 7.627 None None None XRAY 3.0 0.226 0.279 B 336.0 295.0 5 30 30 0 [[999, 1268]] 1.0 3lvp TYR_IGF1R_HUMAN TYR 2.6e-95 324.6 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LVPC P08069 987 1286 1367.0 PDR:3 Type1 Inactive DFGin 6.6016 14.7053 ABAminus -128.34, 8.64 -136.7, 135.21 -140.34, 37.76 307.43, 72.91 -60.45, -40.08 in-out in 9.7766 Saltbr-out 5.7354 HRD-in -80.86, -39.6 60.48, 1.48 out-in-out SNCoio in-out ActLoopNT-in 3.0674 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 53.07, 146.43 APE9-dihe-in -156.81, 103.94 APE8-dihe-in -81.83, 74.27 APE8-rot-na 32.03 APE67-dihe-in -72.67, -15.88 -39.8, -39.1 APE12-dist-na 7.8727 APE11-dist-na 8.677 APE10-dist-na 7.3797 APE9-dist-in 7.06 None None None XRAY 3.0 0.226 0.279 C 336.0 293.0 7 30 28 2 [[999, 1268]] 1.0 3lvp TYR_IGF1R_HUMAN TYR 2.6e-95 324.6 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LVPD P08069 986 1285 1367.0 PDR:4 Type1 None DFGin 6.3057 14.4273 BLAminus -106.91, 166.93 53.44, 123.0 -131.84, 26.68 301.24, 78.21 -46.25, -39.95 in-in in 9.2751 Saltbr-in 3.1286 HRD-in -65.98, -38.21 59.59, -1.0 in-in-none SNCiin in-none ActLoopNT-in 2.8294 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 78.94 APE8-dihe-in -74.27, 72.81 APE8-rot-na 31.79 APE67-dihe-in -58.26, -9.17 -42.05, -56.15 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.2592 None None None XRAY 3.0 0.226 0.279 D 336.0 282.0 18 30 27 3 [[999, 1268]] 1.0 3lvp TYR_IGF1R_HUMAN TYR 2.6e-95 324.6 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor

Ligand: PDR

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 75.0% 3LVPB
DFGin BLAminus 1 25.0% 3LVPD
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR IGF1R IGF1R_HUMAN 3LVPA P08069 989 1286 1367.0 PDR:1 Type1 Inactive DFGin 6.0566 14.1894 ABAminus -121.12, 43.14 -157.44, 127.28 -132.71, 38.65 304.97, 81.73 -58.62, -41.18 in-out in 9.1128 Saltbr-out 6.2341 HRD-in -83.6, -34.91 64.8, -16.89 out-in-in SNCoii in-in ActLoopNT-in 3.2098 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -64.15, 163.21 APE9-dihe-in -98.5, 148.37 APE8-dihe-in -75.76, 55.82 APE8-rot-na 35.7 APE67-dihe-in -60.82, -13.12 -37.4, -57.84 APE12-dist-na 11.8103 APE11-dist-na 10.8587 APE10-dist-na 12.5547 APE9-dist-in 7.7687 None None None XRAY 3.0 0.226 0.279 A 336.0 289.0 9 30 23 7 [[999, 1268]] 1.0 3lvp Homo sapiens TYR_IGF1R_HUMAN TYR 2.6e-95 324.6 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LVPB P08069 986 1285 1367.0 PDR:2 Type1 Inactive DFGin 5.9292 13.6583 ABAminus -100.72, -41.98 -105.19, 149.94 -137.93, 21.74 308.71, 87.7 -51.11, -10.36 in-out in 9.3758 Saltbr-out 4.6992 HRD-in -75.05, -36.77 62.12, -0.15 out-in-in SNCoii in-in ActLoopNT-in 2.8014 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -133.19, 147.36 APE9-dihe-in -73.98, 133.27 APE8-dihe-in -70.94, 67.87 APE8-rot-na 28.67 APE67-dihe-in -66.44, 0.67 -51.66, -49.49 APE12-dist-na 12.7663 APE11-dist-na 10.8475 APE10-dist-na 12.4429 APE9-dist-in 7.627 None None None XRAY 3.0 0.226 0.279 B 336.0 295.0 5 30 30 0 [[999, 1268]] 1.0 3lvp Homo sapiens TYR_IGF1R_HUMAN TYR 2.6e-95 324.6 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LVPC P08069 987 1286 1367.0 PDR:3 Type1 Inactive DFGin 6.6016 14.7053 ABAminus -128.34, 8.64 -136.7, 135.21 -140.34, 37.76 307.43, 72.91 -60.45, -40.08 in-out in 9.7766 Saltbr-out 5.7354 HRD-in -80.86, -39.6 60.48, 1.48 out-in-out SNCoio in-out ActLoopNT-in 3.0674 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 53.07, 146.43 APE9-dihe-in -156.81, 103.94 APE8-dihe-in -81.83, 74.27 APE8-rot-na 32.03 APE67-dihe-in -72.67, -15.88 -39.8, -39.1 APE12-dist-na 7.8727 APE11-dist-na 8.677 APE10-dist-na 7.3797 APE9-dist-in 7.06 None None None XRAY 3.0 0.226 0.279 C 336.0 293.0 7 30 28 2 [[999, 1268]] 1.0 3lvp Homo sapiens TYR_IGF1R_HUMAN TYR 2.6e-95 324.6 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LVPD P08069 986 1285 1367.0 PDR:4 Type1 None DFGin 6.3057 14.4273 BLAminus -106.91, 166.93 53.44, 123.0 -131.84, 26.68 301.24, 78.21 -46.25, -39.95 in-in in 9.2751 Saltbr-in 3.1286 HRD-in -65.98, -38.21 59.59, -1.0 in-in-none SNCiin in-none ActLoopNT-in 2.8294 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 78.94 APE8-dihe-in -74.27, 72.81 APE8-rot-na 31.79 APE67-dihe-in -58.26, -9.17 -42.05, -56.15 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.2592 None None None XRAY 3.0 0.226 0.279 D 336.0 282.0 18 30 27 3 [[999, 1268]] 1.0 3lvp Homo sapiens TYR_IGF1R_HUMAN TYR 2.6e-95 324.6 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor

Ligand: PDR

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name