Ligand: PD1

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 100.0% 2FGIA

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR1 FGFR1_HUMAN 2FGIA P11362 464 762 822.0 PD1:1001 Type1.5_Back Inactive DFGin 5.121 13.427 BLAplus -112.68, 157.47 60.87, 36.89 -81.98, -32.37 53.09, 90.73 -98.47, 17.45 in-in in 7.747 Saltbr-in 2.901 HRD-in -72.72, -53.18 83.95, -27.1 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -126.75, 157.3 APE9-dihe-in -97.93, 112.9 APE8-dihe-out -58.5, -25.56 APE8-rot-na 326.54 APE67-dihe-in -72.23, -8.06 -59.01, -20.89 APE12-dist-na 19.922 APE11-dist-na 21.175 APE10-dist-na 19.322 APE9-dist-out 11.544 L457V,C488A,C584S None None XRAY 2.5 0.204 0.264 A 310 274 25 0 0 2 [[478, 756]] 1.0 2fgi TYR_FGFR1_HUMAN TYR 1.4e-104 354.9 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 2FGIB P11362 461 761 822.0 PD1:1000 Type1.5_Back Inactive DFGin 5.065 13.208 BLAplus -127.21, 161.09 62.19, 18.94 -71.59, -20.95 56.29, 90.56 -106.4, 12.05 in-in in 7.776 Saltbr-in 3.066 HRD-in -62.08, -49.35 70.47, -0.26 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -96.38, 171.1 APE9-dihe-in -103.55, 110.23 APE8-dihe-out -52.66, -22.87 APE8-rot-na 324.05 APE67-dihe-in -65.07, -15.18 -62.56, -23.42 APE12-dist-na 999.0 APE11-dist-na 20.195 APE10-dist-na 19.456 APE9-dist-out 11.655 L457V,C488A,C584S None None XRAY 2.5 0.204 0.264 B 310 272 29 0 0 9 [[478, 756]] 1.0 2fgi TYR_FGFR1_HUMAN TYR 1.4e-104 354.9 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1

Ligand: PD1

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 100.0% 2FGIA

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR1 FGFR1_HUMAN 2FGIA P11362 464 762 822.0 PD1:1001 Type1.5_Back Inactive DFGin 5.121 13.427 BLAplus -112.68, 157.47 60.87, 36.89 -81.98, -32.37 53.09, 90.73 -98.47, 17.45 in-in in 7.747 Saltbr-in 2.901 HRD-in -72.72, -53.18 83.95, -27.1 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -126.75, 157.3 APE9-dihe-in -97.93, 112.9 APE8-dihe-out -58.5, -25.56 APE8-rot-na 326.54 APE67-dihe-in -72.23, -8.06 -59.01, -20.89 APE12-dist-na 19.922 APE11-dist-na 21.175 APE10-dist-na 19.322 APE9-dist-out 11.544 L457V,C488A,C584S None None XRAY 2.5 0.204 0.264 A 310 274 25 0 0 2 [[478, 756]] 1.0 2fgi Homo sapiens TYR_FGFR1_HUMAN TYR 1.4e-104 354.9 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 2FGIB P11362 461 761 822.0 PD1:1000 Type1.5_Back Inactive DFGin 5.065 13.208 BLAplus -127.21, 161.09 62.19, 18.94 -71.59, -20.95 56.29, 90.56 -106.4, 12.05 in-in in 7.776 Saltbr-in 3.066 HRD-in -62.08, -49.35 70.47, -0.26 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -96.38, 171.1 APE9-dihe-in -103.55, 110.23 APE8-dihe-out -52.66, -22.87 APE8-rot-na 324.05 APE67-dihe-in -65.07, -15.18 -62.56, -23.42 APE12-dist-na 999.0 APE11-dist-na 20.195 APE10-dist-na 19.456 APE9-dist-out 11.655 L457V,C488A,C584S None None XRAY 2.5 0.204 0.264 B 310 272 29 0 0 9 [[478, 756]] 1.0 2fgi Homo sapiens TYR_FGFR1_HUMAN TYR 1.4e-104 354.9 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1

Ligand: PD1

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name