Ligand: NTQ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6TPFA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 6TPFA P23458 864 1153 1154.0 NTQ:1201 Type1 Inactive DFGin 6.549 13.566 ABAminus -112.13, 4.42 -147.17, 134.74 -132.51, 36.57 297.52, 87.9 -61.56, -38.59 in-in in 7.907 Saltbr-in 2.723 HRD-in -81.26, -43.5 66.58, 8.45 in-in-out SNCiio in-out ActLoopNT-in 2.755 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -113.97, 47.61 APE9-dihe-in -75.75, 153.17 APE8-dihe-in -82.59, 85.83 APE8-rot-na 32.54 APE67-dihe-in -74.51, -8.6 -66.85, -35.11 APE12-dist-na 10.951 APE11-dist-na 12.702 APE10-dist-na 10.945 APE9-dist-in 6.702 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.31 0.266 0.327 A 291 288 2 0 0 0 [[583, 847], [875, 1151]] 2.0 6tpf TYR_JAK1-2_HUMAN TYR 1.9e-87 298.8 2 259 258 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6TPFB P23458 865 1153 1154.0 NTQ:1201 Type1 Inactive DFGin 6.516 13.607 ABAminus -112.38, 6.69 -146.72, 134.6 -130.81, 35.94 297.58, 85.61 -65.62, -37.25 in-in in 7.843 Saltbr-in 2.72 HRD-in -83.36, -42.45 66.49, 9.9 in-in-out SNCiio in-out ActLoopNT-in 2.762 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 46.13, 45.8 APE9-dihe-in -71.68, 152.43 APE8-dihe-in -82.66, 85.94 APE8-rot-na 32.5 APE67-dihe-in -74.85, -9.43 -66.05, -35.76 APE12-dist-na 10.968 APE11-dist-na 12.342 APE10-dist-na 11.419 APE9-dist-in 6.666 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.31 0.266 0.327 B 291 278 11 0 0 0 [[583, 847], [875, 1151]] 2.0 6tpf TYR_JAK1-2_HUMAN TYR 1.9e-87 298.8 2 259 258 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

Ligand: NTQ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6TPFA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 6TPFA P23458 864 1153 1154.0 NTQ:1201 Type1 Inactive DFGin 6.549 13.566 ABAminus -112.13, 4.42 -147.17, 134.74 -132.51, 36.57 297.52, 87.9 -61.56, -38.59 in-in in 7.907 Saltbr-in 2.723 HRD-in -81.26, -43.5 66.58, 8.45 in-in-out SNCiio in-out ActLoopNT-in 2.755 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -113.97, 47.61 APE9-dihe-in -75.75, 153.17 APE8-dihe-in -82.59, 85.83 APE8-rot-na 32.54 APE67-dihe-in -74.51, -8.6 -66.85, -35.11 APE12-dist-na 10.951 APE11-dist-na 12.702 APE10-dist-na 10.945 APE9-dist-in 6.702 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.31 0.266 0.327 A 291 288 2 0 0 0 [[583, 847], [875, 1151]] 2.0 6tpf Homo sapiens TYR_JAK1-2_HUMAN TYR 1.9e-87 298.8 2 259 258 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6TPFB P23458 865 1153 1154.0 NTQ:1201 Type1 Inactive DFGin 6.516 13.607 ABAminus -112.38, 6.69 -146.72, 134.6 -130.81, 35.94 297.58, 85.61 -65.62, -37.25 in-in in 7.843 Saltbr-in 2.72 HRD-in -83.36, -42.45 66.49, 9.9 in-in-out SNCiio in-out ActLoopNT-in 2.762 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 46.13, 45.8 APE9-dihe-in -71.68, 152.43 APE8-dihe-in -82.66, 85.94 APE8-rot-na 32.5 APE67-dihe-in -74.85, -9.43 -66.05, -35.76 APE12-dist-na 10.968 APE11-dist-na 12.342 APE10-dist-na 11.419 APE9-dist-in 6.666 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.31 0.266 0.327 B 291 278 11 0 0 0 [[583, 847], [875, 1151]] 2.0 6tpf Homo sapiens TYR_JAK1-2_HUMAN TYR 1.9e-87 298.8 2 259 258 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

Ligand: NTQ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name