Ligand: NJ6

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8I0LA
DFGin BLBplus 1 50.0% 8I0MA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK6 CDK6_HUMAN 8I0MA Q00534 11 301 326.0 NJ6:401 Type1 Inactive DFGin 6.558 13.702 BLBplus -148.9, 164.2 63.1, 60.43 -141.6, 158.36 69.2, 85.06 87.02, -3.21 out-none out 12.038 Saltbr-none 999.0 HRD-in -57.52, -54.36 79.68, -19.79 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -65.96 APE8-dihe-in -92.33, 118.65 APE8-rot-in 304.47 APE67-dihe-in -71.06, -15.04 -105.38, 8.52 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.235 None None None XRAY 2.777 0.207 0.282 A 301 260 31 0 0 13 [[13, 300]] 1.0 8i0m CMGC_CDK6_HUMAN CMGC 1.7e-84 290.7 1 301 301 162 163 164 166 168 43 61 65 142 144 143 145 201 189 184 183 182 181 180 179 178 99 Cyclin-dependent kinase 6
CMGC CDK9 CDK9_HUMAN 8I0LA P50750 6 326 372.0 NJ6:401 Type1 Active DFGin 7.293 15.855 BLAminus -130.69, 179.52 57.03, 69.82 -94.01, 27.86 282.24, 73.6 -69.08, -49.61 in-in in 9.573 Saltbr-in 3.235 HRD-in -83.43, -47.61 60.01, 23.96 in-in-in SNCiii in-in ActLoopNT-in 2.759 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.64, 163.64 APE9-dihe-na 68.82, 138.39 APE8-dihe-in -61.18, 156.44 APE8-rot-in 324.35 APE67-dihe-in -70.36, -22.43 -60.05, -41.69 APE12-dist-in 12.809 APE11-dist-in 10.347 APE10-dist-in 6.433 APE9-dist-in 3.549 None TPO186 TPO186 XRAY 3.6 0.235 0.257 A 332 308 13 0 0 5 [[19, 315]] 1.0 8i0l CMGC_CDK9_HUMAN CMGC 3.8e-80 275.2 1 301 301 166 167 168 170 172 48 66 70 146 148 147 149 211 198 193 192 191 190 189 188 187 104 Cyclin-dependent kinase 9

Ligand: NJ6

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8I0LA
DFGin BLBplus 1 50.0% 8I0MA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK6 CDK6_HUMAN 8I0MA Q00534 11 301 326.0 NJ6:401 Type1 Inactive DFGin 6.558 13.702 BLBplus -148.9, 164.2 63.1, 60.43 -141.6, 158.36 69.2, 85.06 87.02, -3.21 out-none out 12.038 Saltbr-none 999.0 HRD-in -57.52, -54.36 79.68, -19.79 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -65.96 APE8-dihe-in -92.33, 118.65 APE8-rot-in 304.47 APE67-dihe-in -71.06, -15.04 -105.38, 8.52 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.235 None None None XRAY 2.777 0.207 0.282 A 301 260 31 0 0 13 [[13, 300]] 1.0 8i0m Homo sapiens CMGC_CDK6_HUMAN CMGC 1.7e-84 290.7 1 301 301 162 163 164 166 168 43 61 65 142 144 143 145 201 189 184 183 182 181 180 179 178 99 Cyclin-dependent kinase 6
CMGC CDK9 CDK9_HUMAN 8I0LA P50750 6 326 372.0 NJ6:401 Type1 Active DFGin 7.293 15.855 BLAminus -130.69, 179.52 57.03, 69.82 -94.01, 27.86 282.24, 73.6 -69.08, -49.61 in-in in 9.573 Saltbr-in 3.235 HRD-in -83.43, -47.61 60.01, 23.96 in-in-in SNCiii in-in ActLoopNT-in 2.759 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.64, 163.64 APE9-dihe-na 68.82, 138.39 APE8-dihe-in -61.18, 156.44 APE8-rot-in 324.35 APE67-dihe-in -70.36, -22.43 -60.05, -41.69 APE12-dist-in 12.809 APE11-dist-in 10.347 APE10-dist-in 6.433 APE9-dist-in 3.549 None TPO186 TPO186 XRAY 3.6 0.235 0.257 A 332 308 13 0 0 5 [[19, 315]] 1.0 8i0l Homo sapiens CMGC_CDK9_HUMAN CMGC 3.8e-80 275.2 1 301 301 166 167 168 170 172 48 66 70 146 148 147 149 211 198 193 192 191 190 189 188 187 104 Cyclin-dependent kinase 9

Ligand: NJ6

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name