Ligand: MVE

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6T8NA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 6T8NA Q04771 203 498 509.0 MVE:604 Type1 Inactive DFGin 8.239 13.5397 BLAminus -117.22, 176.03 72.91, 63.91 -91.39, 23.17 287.75, 168.53 -67.92, -18.8 in-out in 8.9331 Saltbr-out 4.7071 HRD-in -84.95, -51.56 81.75, -3.33 out-in-out SNCoio in-out ActLoopNT-in 2.8153 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -121.51, 167.12 APE9-dihe-na -61.87, 158.02 APE8-dihe-in -61.33, 127.98 APE8-rot-in 306.21 APE67-dihe-in -60.03, -27.55 -64.05, -36.62 APE12-dist-in 10.612 APE11-dist-out 6.6294 APE10-dist-out 9.0873 APE9-dist-in 4.1247 Q207D None None XRAY 1.77 0.205 0.237 A 301.0 293.0 3 32 32 0 [[207, 497]] 1.0 6t8n TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6T8NB Q04771 203 499 509.0 MVE:606 Type1 Inactive DFGin 8.5657 13.4473 BLAminus -115.44, -178.9 71.98, 70.18 -99.66, 24.02 289.42, 166.62 -70.33, -17.84 in-out in 9.0755 Saltbr-out 4.9158 HRD-in -81.57, -50.67 76.26, -0.18 out-in-out SNCoio in-out ActLoopNT-in 2.8995 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -120.64, 165.39 APE9-dihe-na -58.57, 157.21 APE8-dihe-in -58.07, 130.83 APE8-rot-in 301.01 APE67-dihe-in -55.44, -32.97 -60.5, -39.92 APE12-dist-in 10.5281 APE11-dist-out 6.3808 APE10-dist-out 9.1777 APE9-dist-in 4.0381 Q207D None None XRAY 1.77 0.205 0.237 B 301.0 293.0 4 32 32 0 [[207, 497]] 1.0 6t8n TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: MVE

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6T8NA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 6T8NA Q04771 203 498 509.0 MVE:604 Type1 Inactive DFGin 8.239 13.5397 BLAminus -117.22, 176.03 72.91, 63.91 -91.39, 23.17 287.75, 168.53 -67.92, -18.8 in-out in 8.9331 Saltbr-out 4.7071 HRD-in -84.95, -51.56 81.75, -3.33 out-in-out SNCoio in-out ActLoopNT-in 2.8153 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -121.51, 167.12 APE9-dihe-na -61.87, 158.02 APE8-dihe-in -61.33, 127.98 APE8-rot-in 306.21 APE67-dihe-in -60.03, -27.55 -64.05, -36.62 APE12-dist-in 10.612 APE11-dist-out 6.6294 APE10-dist-out 9.0873 APE9-dist-in 4.1247 Q207D None None XRAY 1.77 0.205 0.237 A 301.0 293.0 3 32 32 0 [[207, 497]] 1.0 6t8n Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6T8NB Q04771 203 499 509.0 MVE:606 Type1 Inactive DFGin 8.5657 13.4473 BLAminus -115.44, -178.9 71.98, 70.18 -99.66, 24.02 289.42, 166.62 -70.33, -17.84 in-out in 9.0755 Saltbr-out 4.9158 HRD-in -81.57, -50.67 76.26, -0.18 out-in-out SNCoio in-out ActLoopNT-in 2.8995 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -120.64, 165.39 APE9-dihe-na -58.57, 157.21 APE8-dihe-in -58.07, 130.83 APE8-rot-in 301.01 APE67-dihe-in -55.44, -32.97 -60.5, -39.92 APE12-dist-in 10.5281 APE11-dist-out 6.3808 APE10-dist-out 9.1777 APE9-dist-in 4.0381 Q207D None None XRAY 1.77 0.205 0.237 B 301.0 293.0 4 32 32 0 [[207, 497]] 1.0 6t8n Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: MVE

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name