Ligand: M05

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name

Ligand: M05

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2VO6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_BOVIN 2VO7A P00517 15 351 351.0 M05:61351,M05:61352 Allosteric,Type1 Active DFGin 6.0589 13.3545 BLAminus -112.73, 170.06 64.79, 125.13 -129.63, 24.75 288.96, 78.29 -59.84, -27.0 in-in in 8.9212 Saltbr-in 2.5901 HRD-in -91.38, -48.53 69.14, 8.91 in-in-in SNCiii in-in ActLoopNT-in 2.9119 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.06, 161.81 APE9-dihe-na 128.93, -157.64 APE8-dihe-in -120.9, 132.32 APE8-rot-in 302.18 APE67-dihe-in -59.27, -25.29 -43.22, -50.55 APE12-dist-in 8.1025 APE11-dist-in 11.3217 APE10-dist-in 5.7515 APE9-dist-in 3.6251 None TPO198,SEP339 TPO198,SEP339 XRAY 1.98 0.191 0.241 A 351.0 337.0 0 25 25 0 [[44, 298]] 1.0 2vo7 Bos taurus AGC_PRKACA_BOVIN AGC 1.3e-94 322.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_BOVIN 2VO6A P00517 14 351 351.0 M05:61352 Type1 Active DFGin 6.4346 14.1872 BLAminus -116.69, -177.73 56.84, 84.85 -93.23, 27.76 272.38, 55.86 -61.33, -23.85 in-in in 8.6236 Saltbr-in 2.7502 HRD-in -94.44, -52.03 70.59, 14.63 in-in-in SNCiii in-in ActLoopNT-in 2.9129 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.43, 161.66 APE9-dihe-na 131.96, -159.34 APE8-dihe-in -122.22, 131.28 APE8-rot-in 303.11 APE67-dihe-in -58.4, -24.83 -41.37, -51.96 APE12-dist-in 7.9982 APE11-dist-in 11.3208 APE10-dist-in 5.7969 APE9-dist-in 3.5782 V105T,V124A,L174M,Q182K SEP140,TPO198,SEP339 SEP140,TPO198,SEP339 XRAY 1.97 0.175 0.229 A 351.0 338.0 0 25 25 0 [[44, 298]] 1.0 2vo6 Bos taurus AGC_PRKACA_BOVIN AGC 4.5e-94 320.4 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha

Ligand: M05

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2VO6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_BOVIN 2VO7A P00517 15 351 351.0 M05:61351,M05:61352 Allosteric,Type1 Active DFGin 6.0589 13.3545 BLAminus -112.73, 170.06 64.79, 125.13 -129.63, 24.75 288.96, 78.29 -59.84, -27.0 in-in in 8.9212 Saltbr-in 2.5901 HRD-in -91.38, -48.53 69.14, 8.91 in-in-in SNCiii in-in ActLoopNT-in 2.9119 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.06, 161.81 APE9-dihe-na 128.93, -157.64 APE8-dihe-in -120.9, 132.32 APE8-rot-in 302.18 APE67-dihe-in -59.27, -25.29 -43.22, -50.55 APE12-dist-in 8.1025 APE11-dist-in 11.3217 APE10-dist-in 5.7515 APE9-dist-in 3.6251 None TPO198,SEP339 TPO198,SEP339 XRAY 1.98 0.191 0.241 A 351.0 337.0 0 25 25 0 [[44, 298]] 1.0 2vo7 Bos taurus AGC_PRKACA_BOVIN AGC 1.3e-94 322.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_BOVIN 2VO6A P00517 14 351 351.0 M05:61352 Type1 Active DFGin 6.4346 14.1872 BLAminus -116.69, -177.73 56.84, 84.85 -93.23, 27.76 272.38, 55.86 -61.33, -23.85 in-in in 8.6236 Saltbr-in 2.7502 HRD-in -94.44, -52.03 70.59, 14.63 in-in-in SNCiii in-in ActLoopNT-in 2.9129 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.43, 161.66 APE9-dihe-na 131.96, -159.34 APE8-dihe-in -122.22, 131.28 APE8-rot-in 303.11 APE67-dihe-in -58.4, -24.83 -41.37, -51.96 APE12-dist-in 7.9982 APE11-dist-in 11.3208 APE10-dist-in 5.7969 APE9-dist-in 3.5782 V105T,V124A,L174M,Q182K SEP140,TPO198,SEP339 SEP140,TPO198,SEP339 XRAY 1.97 0.175 0.229 A 351.0 338.0 0 25 25 0 [[44, 298]] 1.0 2vo6 Bos taurus AGC_PRKACA_BOVIN AGC 4.5e-94 320.4 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha