Ligand: LTJ

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 8X2AA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR BMX BMX_HUMAN 8X2AA P51813 411 671 675.0 LTJ:60701 Type1 Inactive DFGin 5.8209 14.0387 BLBplus -128.47, 153.9 62.68, 22.67 -59.22, 131.78 39.16, 96.25 84.88, -10.49 out-out out 14.0857 Saltbr-out 13.5619 HRD-in -66.41, -55.5 86.77, -19.57 out-out-out SNCooo out-out ActLoopNT-out 7.4629 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -85.75, -2.66 APE9-dihe-in -58.35, 128.47 APE8-dihe-in -81.61, 66.73 APE8-rot-na 33.1 APE67-dihe-in -73.37, -10.04 -54.92, -38.05 APE12-dist-na 21.5504 APE11-dist-na 17.6484 APE10-dist-na 14.1924 APE9-dist-out 9.0232 None None None XRAY 1.3 0.129 0.161 A 266.0 258.0 3 29 26 3 [[417, 668]] 1.0 8x2a TYR_BMX_HUMAN TYR 1.9e-93 318.5 1.0 260.0 260.0 553 554 555 557 559 445 460 464 533 535 534 536.0 594 582 577 576 575 574 573 572 571 490 Cytoplasmic tyrosine-protein kinase BMX
TYR BTK BTK_HUMAN 6O8IA Q06187 391 658 659.0 LTJ:4000 Type1 Inactive DFGin 5.5354 14.972 BLBplus -129.8, -155.21 58.3, 44.54 -137.09, 133.38 65.53, 96.57 62.04, -135.93 out-out out 11.7759 Saltbr-out 14.169 HRD-in -73.8, -50.46 77.78, -9.81 out-out-out SNCooo out-out ActLoopNT-out 11.6693 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -85.73, 87.18 APE9-dihe-in -85.79, 141.41 APE8-dihe-in -78.4, 64.22 APE8-rot-na 30.1 APE67-dihe-in -70.0, -10.62 -49.55, -46.25 APE12-dist-na 16.2014 APE11-dist-na 19.9778 APE10-dist-na 18.3131 APE9-dist-out 8.2749 None None None XRAY 1.42 0.195 0.222 A 269.0 260.0 8 29 29 0 [[402, 653]] 1.0 6o8i TYR_BTK_HUMAN TYR 5.9e-93 316.9 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK

Ligand: LTJ

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 8X2AA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR BMX BMX_HUMAN 8X2AA P51813 411 671 675.0 LTJ:60701 Type1 Inactive DFGin 5.8209 14.0387 BLBplus -128.47, 153.9 62.68, 22.67 -59.22, 131.78 39.16, 96.25 84.88, -10.49 out-out out 14.0857 Saltbr-out 13.5619 HRD-in -66.41, -55.5 86.77, -19.57 out-out-out SNCooo out-out ActLoopNT-out 7.4629 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -85.75, -2.66 APE9-dihe-in -58.35, 128.47 APE8-dihe-in -81.61, 66.73 APE8-rot-na 33.1 APE67-dihe-in -73.37, -10.04 -54.92, -38.05 APE12-dist-na 21.5504 APE11-dist-na 17.6484 APE10-dist-na 14.1924 APE9-dist-out 9.0232 None None None XRAY 1.3 0.129 0.161 A 266.0 258.0 3 29 26 3 [[417, 668]] 1.0 8x2a Homo sapiens TYR_BMX_HUMAN TYR 1.9e-93 318.5 1.0 260.0 260.0 553 554 555 557 559 445 460 464 533 535 534 536.0 594 582 577 576 575 574 573 572 571 490 Cytoplasmic tyrosine-protein kinase BMX
TYR BTK BTK_HUMAN 6O8IA Q06187 391 658 659.0 LTJ:4000 Type1 Inactive DFGin 5.5354 14.972 BLBplus -129.8, -155.21 58.3, 44.54 -137.09, 133.38 65.53, 96.57 62.04, -135.93 out-out out 11.7759 Saltbr-out 14.169 HRD-in -73.8, -50.46 77.78, -9.81 out-out-out SNCooo out-out ActLoopNT-out 11.6693 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -85.73, 87.18 APE9-dihe-in -85.79, 141.41 APE8-dihe-in -78.4, 64.22 APE8-rot-na 30.1 APE67-dihe-in -70.0, -10.62 -49.55, -46.25 APE12-dist-na 16.2014 APE11-dist-na 19.9778 APE10-dist-na 18.3131 APE9-dist-out 8.2749 None None None XRAY 1.42 0.195 0.222 A 269.0 260.0 8 29 29 0 [[402, 653]] 1.0 6o8i Homo sapiens TYR_BTK_HUMAN TYR 5.9e-93 316.9 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK

Ligand: LTJ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name