Ligand: LOW

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name

Ligand: LOW

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 6SOVA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_MOUSE 6SOVA P47811 6 359 360.0 SB4:401,LOT:406,LOW:407 Type1,Allosteric,Allosteric Inactive DFGin 5.7849 14.0824 BLBplus -138.85, 169.33 61.87, 30.79 -84.92, 158.4 45.37, 91.9 65.06, 17.43 in-in in 9.109 Saltbr-in 2.6841 HRD-in -76.78, -56.48 78.7, -16.8 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -119.14, 115.02 APE9-dihe-na -91.52, 150.5 APE8-dihe-in -73.47, 137.08 APE8-rot-out 187.92 APE67-dihe-in -63.35, -21.25 -104.06, 1.09 APE12-dist-none 999.0 APE11-dist-out 14.2686 APE10-dist-out 17.8733 APE9-dist-out 10.6949 None None None XRAY 1.31 0.222 0.236 A 361.0 345.0 9 25 16 9 [[24, 308]] 1.0 6sov Mus musculus CMGC_MAPK14_MOUSE CMGC 5.1e-85 291.4 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_MOUSE 6SPLA P47811 6 359 360.0 SB4:401,LOW:407,LOW:408,LOW:409 Type1,Allosteric,Type1,Allosteric Inactive DFGin 5.7888 14.0854 BLBplus -138.3, 168.28 62.33, 31.95 -86.41, 154.5 45.54, 89.73 64.4, 18.17 in-in in 9.0762 Saltbr-in 2.6411 HRD-in -75.83, -58.19 80.85, -15.09 in-out-out SNCioo out-out ActLoopNT-out 9.5477 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -119.05, 110.89 APE9-dihe-na -86.15, 150.38 APE8-dihe-in -72.29, 139.09 APE8-rot-out 187.06 APE67-dihe-in -62.58, -21.12 -105.6, 1.04 APE12-dist-none 999.0 APE11-dist-out 14.3304 APE10-dist-out 17.9596 APE9-dist-out 10.672 None None None XRAY 1.38 0.212 0.225 A 361.0 345.0 9 25 16 9 [[24, 308]] 1.0 6spl Mus musculus CMGC_MAPK14_MOUSE CMGC 5.1e-85 291.4 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: LOW

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 6SOVA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_MOUSE 6SOVA P47811 6 359 360.0 SB4:401,LOT:406,LOW:407 Type1,Allosteric,Allosteric Inactive DFGin 5.7849 14.0824 BLBplus -138.85, 169.33 61.87, 30.79 -84.92, 158.4 45.37, 91.9 65.06, 17.43 in-in in 9.109 Saltbr-in 2.6841 HRD-in -76.78, -56.48 78.7, -16.8 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -119.14, 115.02 APE9-dihe-na -91.52, 150.5 APE8-dihe-in -73.47, 137.08 APE8-rot-out 187.92 APE67-dihe-in -63.35, -21.25 -104.06, 1.09 APE12-dist-none 999.0 APE11-dist-out 14.2686 APE10-dist-out 17.8733 APE9-dist-out 10.6949 None None None XRAY 1.31 0.222 0.236 A 361.0 345.0 9 25 16 9 [[24, 308]] 1.0 6sov Mus musculus CMGC_MAPK14_MOUSE CMGC 5.1e-85 291.4 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_MOUSE 6SPLA P47811 6 359 360.0 SB4:401,LOW:407,LOW:408,LOW:409 Type1,Allosteric,Type1,Allosteric Inactive DFGin 5.7888 14.0854 BLBplus -138.3, 168.28 62.33, 31.95 -86.41, 154.5 45.54, 89.73 64.4, 18.17 in-in in 9.0762 Saltbr-in 2.6411 HRD-in -75.83, -58.19 80.85, -15.09 in-out-out SNCioo out-out ActLoopNT-out 9.5477 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -119.05, 110.89 APE9-dihe-na -86.15, 150.38 APE8-dihe-in -72.29, 139.09 APE8-rot-out 187.06 APE67-dihe-in -62.58, -21.12 -105.6, 1.04 APE12-dist-none 999.0 APE11-dist-out 14.3304 APE10-dist-out 17.9596 APE9-dist-out 10.672 None None None XRAY 1.38 0.212 0.225 A 361.0 345.0 9 25 16 9 [[24, 308]] 1.0 6spl Mus musculus CMGC_MAPK14_MOUSE CMGC 5.1e-85 291.4 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14