Ligand: LOT

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name

Ligand: LOT

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 100.0% 6SP9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_MOUSE 6SOVA P47811 6 359 360.0 SB4:401,LOT:406,LOW:407 Type1,Allosteric,Allosteric Inactive DFGin 5.7849 14.0824 BLBplus -138.85, 169.33 61.87, 30.79 -84.92, 158.4 45.37, 91.9 65.06, 17.43 in-in in 9.109 Saltbr-in 2.6841 HRD-in -76.78, -56.48 78.7, -16.8 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -119.14, 115.02 APE9-dihe-na -91.52, 150.5 APE8-dihe-in -73.47, 137.08 APE8-rot-out 187.92 APE67-dihe-in -63.35, -21.25 -104.06, 1.09 APE12-dist-none 999.0 APE11-dist-out 14.2686 APE10-dist-out 17.8733 APE9-dist-out 10.6949 None None None XRAY 1.31 0.222 0.236 A 361.0 345.0 9 25 16 9 [[24, 308]] 1.0 6sov Mus musculus CMGC_MAPK14_MOUSE CMGC 5.1e-85 291.4 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_MOUSE 6SP9A P47811 5 359 360.0 SB4:401,LOT:407,LOT:408 Type1,Allosteric,Allosteric Inactive DFGin 5.7449 14.0248 BLBplus -140.9, 168.52 62.86, 31.59 -87.26, 153.1 44.44, 90.21 64.02, 999.0 in-in in 9.1125 Saltbr-in 2.6859 HRD-in -74.78, -57.56 80.54, -13.75 in-out-out SNCioo out-out ActLoopNT-out 10.2704 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na -121.16, 112.82 APE9-dihe-na -87.42, 149.28 APE8-dihe-in -72.91, 139.05 APE8-rot-out 186.67 APE67-dihe-in -63.91, -20.89 -106.74, 1.89 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.6765 None None None XRAY 1.22 0.221 0.235 A 361.0 348.0 7 25 18 7 [[24, 308]] 1.0 6sp9 Mus musculus CMGC_MAPK14_MOUSE CMGC 5.1e-85 291.4 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_MOUSE 6Y7YA P47811 6 359 360.0 SB4:401,OFQ:407,LOT:408,LOT:409 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 5.5985 14.0658 BLBplus -134.15, 167.21 61.56, 33.57 -84.2, 154.3 46.03, 91.51 71.1, 10.08 in-in in 9.0829 Saltbr-in 2.4631 HRD-in -77.03, -55.9 76.47, -10.86 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 124.77 APE9-dihe-na -96.71, 148.3 APE8-dihe-in -61.68, 139.31 APE8-rot-in 301.71 APE67-dihe-in -65.13, -20.59 -107.51, 1.3 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 17.6132 APE9-dist-out 10.7375 C162S None None XRAY 1.51 0.221 0.248 A 360.0 343.0 11 25 14 11 [[24, 308]] 1.0 6y7y Mus musculus CMGC_MAPK14_MOUSE CMGC 5.1e-85 291.4 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: LOT

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 100.0% 6SP9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK14 MK14_MOUSE 6SOVA P47811 6 359 360.0 SB4:401,LOT:406,LOW:407 Type1,Allosteric,Allosteric Inactive DFGin 5.7849 14.0824 BLBplus -138.85, 169.33 61.87, 30.79 -84.92, 158.4 45.37, 91.9 65.06, 17.43 in-in in 9.109 Saltbr-in 2.6841 HRD-in -76.78, -56.48 78.7, -16.8 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na -119.14, 115.02 APE9-dihe-na -91.52, 150.5 APE8-dihe-in -73.47, 137.08 APE8-rot-out 187.92 APE67-dihe-in -63.35, -21.25 -104.06, 1.09 APE12-dist-none 999.0 APE11-dist-out 14.2686 APE10-dist-out 17.8733 APE9-dist-out 10.6949 None None None XRAY 1.31 0.222 0.236 A 361.0 345.0 9 25 16 9 [[24, 308]] 1.0 6sov Mus musculus CMGC_MAPK14_MOUSE CMGC 5.1e-85 291.4 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_MOUSE 6SP9A P47811 5 359 360.0 SB4:401,LOT:407,LOT:408 Type1,Allosteric,Allosteric Inactive DFGin 5.7449 14.0248 BLBplus -140.9, 168.52 62.86, 31.59 -87.26, 153.1 44.44, 90.21 64.02, 999.0 in-in in 9.1125 Saltbr-in 2.6859 HRD-in -74.78, -57.56 80.54, -13.75 in-out-out SNCioo out-out ActLoopNT-out 10.2704 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na -121.16, 112.82 APE9-dihe-na -87.42, 149.28 APE8-dihe-in -72.91, 139.05 APE8-rot-out 186.67 APE67-dihe-in -63.91, -20.89 -106.74, 1.89 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.6765 None None None XRAY 1.22 0.221 0.235 A 361.0 348.0 7 25 18 7 [[24, 308]] 1.0 6sp9 Mus musculus CMGC_MAPK14_MOUSE CMGC 5.1e-85 291.4 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_MOUSE 6Y7YA P47811 6 359 360.0 SB4:401,OFQ:407,LOT:408,LOT:409 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 5.5985 14.0658 BLBplus -134.15, 167.21 61.56, 33.57 -84.2, 154.3 46.03, 91.51 71.1, 10.08 in-in in 9.0829 Saltbr-in 2.4631 HRD-in -77.03, -55.9 76.47, -10.86 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 124.77 APE9-dihe-na -96.71, 148.3 APE8-dihe-in -61.68, 139.31 APE8-rot-in 301.71 APE67-dihe-in -65.13, -20.59 -107.51, 1.3 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 17.6132 APE9-dist-out 10.7375 C162S None None XRAY 1.51 0.221 0.248 A 360.0 343.0 11 25 14 11 [[24, 308]] 1.0 6y7y Mus musculus CMGC_MAPK14_MOUSE CMGC 5.1e-85 291.4 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14