Ligand: LKT

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6SM8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 6SM8B P23458 865 1154 1154.0 LKT:61201 Type1 Inactive DFGin 6.8061 13.6678 ABAminus -102.82, -5.52 -148.54, 142.3 -131.39, 24.74 291.91, 87.01 -56.81, -29.39 in-in in 7.8014 Saltbr-in 2.7112 HRD-in -72.52, -51.3 71.87, 8.95 in-in-out SNCiio in-out ActLoopNT-in 2.8319 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -108.32, 29.21 APE9-dihe-in -64.29, 137.39 APE8-dihe-in -82.59, 73.84 APE8-rot-na 28.56 APE67-dihe-in -76.5, -2.32 -51.19, -31.92 APE12-dist-na 11.5209 APE11-dist-na 13.3431 APE10-dist-na 10.3287 APE9-dist-in 6.6704 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.85 0.213 0.241 B 301.0 284.0 6 31 29 2 [[583, 847], [875, 1151]] 2.0 6sm8 TYR_JAK1-2_HUMAN TYR 2.1e-87 298.7 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6SM8A P23458 854 1154 1154.0 LKT:61201 Type1 Inactive DFGin 6.8129 13.706 ABAminus -101.63, -7.1 -147.81, 142.33 -131.41, 24.39 292.89, 86.49 -54.23, -31.63 in-in in 7.8069 Saltbr-in 2.7315 HRD-in -72.9, -49.47 70.53, 3.61 in-in-out SNCiio in-out ActLoopNT-in 2.8357 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -103.89, 30.48 APE9-dihe-in -64.02, 138.21 APE8-dihe-in -82.49, 73.83 APE8-rot-na 29.16 APE67-dihe-in -76.27, -2.8 -50.53, -32.36 APE12-dist-na 11.4381 APE11-dist-na 13.2197 APE10-dist-na 10.2463 APE9-dist-in 6.7238 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.85 0.213 0.241 A 302.0 296.0 5 31 31 0 [[583, 847], [875, 1151]] 2.0 6sm8 TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

Ligand: LKT

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6SM8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 6SM8B P23458 865 1154 1154.0 LKT:61201 Type1 Inactive DFGin 6.8061 13.6678 ABAminus -102.82, -5.52 -148.54, 142.3 -131.39, 24.74 291.91, 87.01 -56.81, -29.39 in-in in 7.8014 Saltbr-in 2.7112 HRD-in -72.52, -51.3 71.87, 8.95 in-in-out SNCiio in-out ActLoopNT-in 2.8319 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -108.32, 29.21 APE9-dihe-in -64.29, 137.39 APE8-dihe-in -82.59, 73.84 APE8-rot-na 28.56 APE67-dihe-in -76.5, -2.32 -51.19, -31.92 APE12-dist-na 11.5209 APE11-dist-na 13.3431 APE10-dist-na 10.3287 APE9-dist-in 6.6704 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.85 0.213 0.241 B 301.0 284.0 6 31 29 2 [[583, 847], [875, 1151]] 2.0 6sm8 Homo sapiens TYR_JAK1-2_HUMAN TYR 2.1e-87 298.7 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6SM8A P23458 854 1154 1154.0 LKT:61201 Type1 Inactive DFGin 6.8129 13.706 ABAminus -101.63, -7.1 -147.81, 142.33 -131.41, 24.39 292.89, 86.49 -54.23, -31.63 in-in in 7.8069 Saltbr-in 2.7315 HRD-in -72.9, -49.47 70.53, 3.61 in-in-out SNCiio in-out ActLoopNT-in 2.8357 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -103.89, 30.48 APE9-dihe-in -64.02, 138.21 APE8-dihe-in -82.49, 73.83 APE8-rot-na 29.16 APE67-dihe-in -76.27, -2.8 -50.53, -32.36 APE12-dist-na 11.4381 APE11-dist-na 13.2197 APE10-dist-na 10.2463 APE9-dist-in 6.7238 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.85 0.213 0.241 A 302.0 296.0 5 31 31 0 [[583, 847], [875, 1151]] 2.0 6sm8 Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

Ligand: LKT

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name