Ligand: KA4

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 6N3NA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
OTHER EIF2AK4-2 E2AK4_HUMAN 6N3NA 3.01 Inactive DFGin‑BLAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn KA4 Type1 584 - 1003 0 None K807A,D848N,T899E,T904E eIF-2-alpha kinase GCN2

Ligand: KA4

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 6N3NA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER EIF2AK4-2 E2AK4_HUMAN 6N3NA 3.01 Inactive DFGin‑BLAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn KA4 Type1 584 - 1003 0 None K807A,D848N,T899E,T904E eIF-2-alpha kinase GCN2 Homo sapiens

Ligand: KA4

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism