Ligand: JRE

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 2 100.0% 6R3SA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK8 CDK8_HUMAN 6R3SA P49336 1 362 464.0 JRE:60501 Type1 Inactive DFGin 6.4489 13.1166 BLBminus -136.26, 169.85 57.34, 42.45 -52.43, 144.8 287.58, 63.16 -78.12, 79.2 in-in in 9.3756 Saltbr-in 2.8296 HRD-in -80.26, -51.73 75.92, 4.6 in-out-out SNCioo out-out ActLoopNT-out 8.6882 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 130.83 APE8-rot-out 181.78 APE67-dihe-in -67.95, -25.35 -103.82, 11.06 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.19 0.202 0.227 A 406.0 343.0 19 31 22 9 [[22, 335]] 1.0 6r3s CMGC_CDK8_HUMAN CMGC 5.9e-82 281.4 5.0 301.0 297.0 172 173 174 176 178 52 66 70 148 150 149 151.0 216 203 198 197 196 195 194 193 192 98 Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 6Y0AA P49336 1 362 464.0 JRE:60501 Type1 Inactive DFGin 6.4489 13.1166 BLBminus -136.26, 169.85 57.34, 42.45 -52.43, 144.8 287.58, 63.16 -78.12, 79.2 in-in in 9.3756 Saltbr-in 2.8296 HRD-in -80.26, -51.73 75.92, 4.6 in-out-out SNCioo out-out ActLoopNT-out 8.6882 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 130.83 APE8-rot-out 181.78 APE67-dihe-in -67.95, -25.35 -103.82, 11.06 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.19 0.202 0.227 A 406.0 343.0 19 31 22 9 [[22, 335]] 1.0 6y0a CMGC_CDK8_HUMAN CMGC 5.9e-82 281.4 5.0 301.0 297.0 172 173 174 176 178 52 66 70 148 150 149 151.0 216 203 198 197 196 195 194 193 192 98 Cyclin-dependent kinase 8

Ligand: JRE

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 2 100.0% 6R3SA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK8 CDK8_HUMAN 6R3SA P49336 1 362 464.0 JRE:60501 Type1 Inactive DFGin 6.4489 13.1166 BLBminus -136.26, 169.85 57.34, 42.45 -52.43, 144.8 287.58, 63.16 -78.12, 79.2 in-in in 9.3756 Saltbr-in 2.8296 HRD-in -80.26, -51.73 75.92, 4.6 in-out-out SNCioo out-out ActLoopNT-out 8.6882 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 130.83 APE8-rot-out 181.78 APE67-dihe-in -67.95, -25.35 -103.82, 11.06 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.19 0.202 0.227 A 406.0 343.0 19 31 22 9 [[22, 335]] 1.0 6r3s Homo sapiens CMGC_CDK8_HUMAN CMGC 5.9e-82 281.4 5.0 301.0 297.0 172 173 174 176 178 52 66 70 148 150 149 151.0 216 203 198 197 196 195 194 193 192 98 Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 6Y0AA P49336 1 362 464.0 JRE:60501 Type1 Inactive DFGin 6.4489 13.1166 BLBminus -136.26, 169.85 57.34, 42.45 -52.43, 144.8 287.58, 63.16 -78.12, 79.2 in-in in 9.3756 Saltbr-in 2.8296 HRD-in -80.26, -51.73 75.92, 4.6 in-out-out SNCioo out-out ActLoopNT-out 8.6882 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 130.83 APE8-rot-out 181.78 APE67-dihe-in -67.95, -25.35 -103.82, 11.06 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.19 0.202 0.227 A 406.0 343.0 19 31 22 9 [[22, 335]] 1.0 6y0a Homo sapiens CMGC_CDK8_HUMAN CMGC 5.9e-82 281.4 5.0 301.0 297.0 172 173 174 176 178 52 66 70 148 150 149 151.0 216 203 198 197 196 195 194 193 192 98 Cyclin-dependent kinase 8

Ligand: JRE

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name