Ligand: ISQ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name

Ligand: ISQ

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6YPPA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_CRIGR 6F14A P25321 9 351 351.0 ISQ:60401 Type1 Active DFGin 6.0674 14.2043 BLAminus -122.05, 170.08 68.01, 92.59 -99.92, 26.02 274.99, 58.24 -62.07, -22.2 in-in in 8.9109 Saltbr-in 2.7518 HRD-in -91.1, -51.98 71.1, 14.05 in-in-in SNCiii in-in ActLoopNT-in 2.9748 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.36, 162.19 APE9-dihe-na 130.64, -162.57 APE8-dihe-in -117.18, 137.06 APE8-rot-in 303.3 APE67-dihe-in -57.84, -25.17 -52.4, -48.63 APE12-dist-in 8.0928 APE11-dist-in 11.4976 APE10-dist-in 5.9364 APE9-dist-in 3.6185 None TPO198,SEP339 TPO198,SEP339 XRAY 1.867 0.176 0.209 A 351.0 339.0 4 25 25 0 [[44, 298]] 1.0 6f14 Cricetulus griseus AGC_PRKACA_CRIGR AGC 6.5e-95 323.3 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_CRIGR 6YPPA P25321 13 351 351.0 ISQ:60401 Type1 Active DFGin 6.575 13.8991 BLAminus -125.47, 168.17 69.21, 91.25 -102.12, 26.99 282.19, 66.61 -59.38, -28.47 in-in in 8.4767 Saltbr-in 2.8285 HRD-in -95.67, -54.73 76.34, 8.75 in-in-in SNCiii in-in ActLoopNT-in 2.9182 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.07, 157.89 APE9-dihe-na 135.57, -161.87 APE8-dihe-in -121.03, 135.18 APE8-rot-in 300.65 APE67-dihe-in -60.09, -21.93 -50.41, -52.89 APE12-dist-in 8.005 APE11-dist-in 11.2134 APE10-dist-in 5.7336 APE9-dist-in 3.8634 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 1.75 0.179 0.203 A 353.0 337.0 2 25 25 0 [[44, 298]] 1.0 6ypp Cricetulus griseus AGC_PRKACA_CRIGR AGC 6.6e-95 323.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha

Ligand: ISQ

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6YPPA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_CRIGR 6F14A P25321 9 351 351.0 ISQ:60401 Type1 Active DFGin 6.0674 14.2043 BLAminus -122.05, 170.08 68.01, 92.59 -99.92, 26.02 274.99, 58.24 -62.07, -22.2 in-in in 8.9109 Saltbr-in 2.7518 HRD-in -91.1, -51.98 71.1, 14.05 in-in-in SNCiii in-in ActLoopNT-in 2.9748 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.36, 162.19 APE9-dihe-na 130.64, -162.57 APE8-dihe-in -117.18, 137.06 APE8-rot-in 303.3 APE67-dihe-in -57.84, -25.17 -52.4, -48.63 APE12-dist-in 8.0928 APE11-dist-in 11.4976 APE10-dist-in 5.9364 APE9-dist-in 3.6185 None TPO198,SEP339 TPO198,SEP339 XRAY 1.867 0.176 0.209 A 351.0 339.0 4 25 25 0 [[44, 298]] 1.0 6f14 Cricetulus griseus AGC_PRKACA_CRIGR AGC 6.5e-95 323.3 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC PRKACA KAPCA_CRIGR 6YPPA P25321 13 351 351.0 ISQ:60401 Type1 Active DFGin 6.575 13.8991 BLAminus -125.47, 168.17 69.21, 91.25 -102.12, 26.99 282.19, 66.61 -59.38, -28.47 in-in in 8.4767 Saltbr-in 2.8285 HRD-in -95.67, -54.73 76.34, 8.75 in-in-in SNCiii in-in ActLoopNT-in 2.9182 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.07, 157.89 APE9-dihe-na 135.57, -161.87 APE8-dihe-in -121.03, 135.18 APE8-rot-in 300.65 APE67-dihe-in -60.09, -21.93 -50.41, -52.89 APE12-dist-in 8.005 APE11-dist-in 11.2134 APE10-dist-in 5.7336 APE9-dist-in 3.8634 None SEP11,TPO198,SEP339 SEP11,TPO198,SEP339 XRAY 1.75 0.179 0.203 A 353.0 337.0 2 25 25 0 [[44, 298]] 1.0 6ypp Cricetulus griseus AGC_PRKACA_CRIGR AGC 6.6e-95 323.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha