Ligand: IR2

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6GINA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 6GINA Q04771 204 499 509.0 IR2:501 Type1 Inactive DFGin 7.8789 13.3121 BLAminus -121.27, 164.65 78.13, 83.84 -95.5, 20.22 297.8, 169.45 -69.16, -15.6 in-out in 8.8782 Saltbr-out 4.8716 HRD-in -75.63, -62.52 83.49, -5.41 out-in-out SNCoio in-out ActLoopNT-in 2.931 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -119.0, 167.37 APE9-dihe-na -63.42, 166.06 APE8-dihe-in -62.49, 126.47 APE8-rot-in 300.53 APE67-dihe-in -54.65, -29.35 -62.43, -43.34 APE12-dist-in 10.6651 APE11-dist-out 6.7216 APE10-dist-out 9.047 APE9-dist-in 3.9149 Q207D None None XRAY 2.2 0.175 0.228 A 301.0 296.0 0 32 32 0 [[207, 497]] 1.0 6gin TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6GINB Q04771 204 499 509.0 IR2:501 Type1 Inactive DFGin 8.4702 13.2553 BLAminus -117.85, 169.5 76.39, 82.56 -95.36, 20.36 297.72, 170.4 -61.59, -30.68 in-out in 9.1209 Saltbr-out 5.2297 HRD-in -83.85, -57.15 83.89, -5.86 out-in-out SNCoio in-out ActLoopNT-in 2.9236 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -128.3, 164.88 APE9-dihe-na -62.2, 169.83 APE8-dihe-in -64.53, 122.81 APE8-rot-in 301.07 APE67-dihe-in -53.52, -33.94 -60.13, -39.73 APE12-dist-in 10.7239 APE11-dist-out 6.7796 APE10-dist-out 8.7392 APE9-dist-in 3.9467 Q207D None None XRAY 2.2 0.175 0.228 B 301.0 296.0 0 32 32 0 [[207, 497]] 1.0 6gin TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: IR2

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6GINA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 6GINA Q04771 204 499 509.0 IR2:501 Type1 Inactive DFGin 7.8789 13.3121 BLAminus -121.27, 164.65 78.13, 83.84 -95.5, 20.22 297.8, 169.45 -69.16, -15.6 in-out in 8.8782 Saltbr-out 4.8716 HRD-in -75.63, -62.52 83.49, -5.41 out-in-out SNCoio in-out ActLoopNT-in 2.931 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -119.0, 167.37 APE9-dihe-na -63.42, 166.06 APE8-dihe-in -62.49, 126.47 APE8-rot-in 300.53 APE67-dihe-in -54.65, -29.35 -62.43, -43.34 APE12-dist-in 10.6651 APE11-dist-out 6.7216 APE10-dist-out 9.047 APE9-dist-in 3.9149 Q207D None None XRAY 2.2 0.175 0.228 A 301.0 296.0 0 32 32 0 [[207, 497]] 1.0 6gin Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6GINB Q04771 204 499 509.0 IR2:501 Type1 Inactive DFGin 8.4702 13.2553 BLAminus -117.85, 169.5 76.39, 82.56 -95.36, 20.36 297.72, 170.4 -61.59, -30.68 in-out in 9.1209 Saltbr-out 5.2297 HRD-in -83.85, -57.15 83.89, -5.86 out-in-out SNCoio in-out ActLoopNT-in 2.9236 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -128.3, 164.88 APE9-dihe-na -62.2, 169.83 APE8-dihe-in -64.53, 122.81 APE8-rot-in 301.07 APE67-dihe-in -53.52, -33.94 -60.13, -39.73 APE12-dist-in 10.7239 APE11-dist-out 6.7796 APE10-dist-out 8.7392 APE9-dist-in 3.9467 Q207D None None XRAY 2.2 0.175 0.228 B 301.0 296.0 0 32 32 0 [[207, 497]] 1.0 6gin Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: IR2

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name