Ligand: I90

Total number of chains: 3
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 9QSRA
DFGin BLBplus 1 33.3% 7Y4TA
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CSNK2A1 CSK21_HUMAN 9QSRA P68400 3 332 391.0 A1I90:401 Type1 Inactive DFGin 7.473 16.276 BLAminus -129.4, -153.69 17.2, 93.17 -99.12, 25.83 303.65, 76.74 -71.34, -17.24 in-in in 9.407 Saltbr-in 3.215 HRD-in -68.5, -47.24 76.3, 1.94 in-in-out SNCiio in-out ActLoopNT-in 2.884 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.84, 158.95 APE9-dihe-na 64.32, 165.47 APE8-dihe-in -94.63, 158.49 APE8-rot-out 46.58 APE67-dihe-in -73.19, -15.03 -52.94, -40.64 APE12-dist-in 12.915 APE11-dist-in 10.887 APE10-dist-in 6.187 APE9-dist-in 3.733 None None None XRAY 2.83 0.271 0.326 A 359 330 0 0 0 0 [[39, 324]] 1.0 9qsr CMGC_CSNK2A1_HUMAN CMGC 1.7e-69 240.3 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 9QSRB P68400 3 332 391.0 A1I90:403 Type1 Active DFGin 7.608 16.326 BLAminus -123.77, -178.88 43.48, 81.0 -91.13, 29.86 305.89, 77.96 -70.55, -24.4 in-in in 9.58 Saltbr-in 2.823 HRD-in -73.55, -45.34 71.01, 12.46 in-in-in SNCiii in-in ActLoopNT-in 2.856 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -115.95, 174.4 APE9-dihe-na 63.95, 172.55 APE8-dihe-in -98.84, 149.46 APE8-rot-in 273.88 APE67-dihe-in -66.6, -1.96 -43.09, -61.5 APE12-dist-in 12.681 APE11-dist-in 10.643 APE10-dist-in 6.474 APE9-dist-in 3.561 None None None XRAY 2.83 0.271 0.326 B 359 330 0 0 0 0 [[39, 324]] 1.0 9qsr CMGC_CSNK2A1_HUMAN CMGC 1.7e-69 240.3 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
TYR MET MET_HUMAN 7Y4TA P08581 1063 1345 1390.0 I90:1401 Type1 Inactive DFGin 5.023 14.284 BLBplus -124.58, -158.37 55.95, 54.1 -154.01, 158.71 78.56, 97.12 63.89, -132.14 out-none out 15.195 Saltbr-none 999.0 HRD-in -78.32, -47.01 69.41, -2.23 none-out-in SNCnoi out-in ActLoopNT-out 10.674 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -96.01, 118.18 APE9-dihe-in -113.5, 113.09 APE8-dihe-in -81.35, 89.51 APE8-rot-na 28.65 APE67-dihe-in -80.22, 3.63 -53.84, -52.52 APE12-dist-na 17.236 APE11-dist-na 17.468 APE10-dist-na 14.752 APE9-dist-in 6.875 None None None XRAY 2.16 0.216 0.251 A 309 281 2 0 0 0 [[1078, 1339]] 1.0 7y4t TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor

Ligand: I90

Total number of chains: 3
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 9QSRA
DFGin BLBplus 1 33.3% 7Y4TA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CSNK2A1 CSK21_HUMAN 9QSRA P68400 3 332 391.0 A1I90:401 Type1 Inactive DFGin 7.473 16.276 BLAminus -129.4, -153.69 17.2, 93.17 -99.12, 25.83 303.65, 76.74 -71.34, -17.24 in-in in 9.407 Saltbr-in 3.215 HRD-in -68.5, -47.24 76.3, 1.94 in-in-out SNCiio in-out ActLoopNT-in 2.884 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -134.84, 158.95 APE9-dihe-na 64.32, 165.47 APE8-dihe-in -94.63, 158.49 APE8-rot-out 46.58 APE67-dihe-in -73.19, -15.03 -52.94, -40.64 APE12-dist-in 12.915 APE11-dist-in 10.887 APE10-dist-in 6.187 APE9-dist-in 3.733 None None None XRAY 2.83 0.271 0.326 A 359 330 0 0 0 0 [[39, 324]] 1.0 9qsr Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.7e-69 240.3 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 9QSRB P68400 3 332 391.0 A1I90:403 Type1 Active DFGin 7.608 16.326 BLAminus -123.77, -178.88 43.48, 81.0 -91.13, 29.86 305.89, 77.96 -70.55, -24.4 in-in in 9.58 Saltbr-in 2.823 HRD-in -73.55, -45.34 71.01, 12.46 in-in-in SNCiii in-in ActLoopNT-in 2.856 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -115.95, 174.4 APE9-dihe-na 63.95, 172.55 APE8-dihe-in -98.84, 149.46 APE8-rot-in 273.88 APE67-dihe-in -66.6, -1.96 -43.09, -61.5 APE12-dist-in 12.681 APE11-dist-in 10.643 APE10-dist-in 6.474 APE9-dist-in 3.561 None None None XRAY 2.83 0.271 0.326 B 359 330 0 0 0 0 [[39, 324]] 1.0 9qsr Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.7e-69 240.3 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
TYR MET MET_HUMAN 7Y4TA P08581 1063 1345 1390.0 I90:1401 Type1 Inactive DFGin 5.023 14.284 BLBplus -124.58, -158.37 55.95, 54.1 -154.01, 158.71 78.56, 97.12 63.89, -132.14 out-none out 15.195 Saltbr-none 999.0 HRD-in -78.32, -47.01 69.41, -2.23 none-out-in SNCnoi out-in ActLoopNT-out 10.674 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -96.01, 118.18 APE9-dihe-in -113.5, 113.09 APE8-dihe-in -81.35, 89.51 APE8-rot-na 28.65 APE67-dihe-in -80.22, 3.63 -53.84, -52.52 APE12-dist-na 17.236 APE11-dist-na 17.468 APE10-dist-na 14.752 APE9-dist-in 6.875 None None None XRAY 2.16 0.216 0.251 A 309 281 2 0 0 0 [[1078, 1339]] 1.0 7y4t Homo sapiens TYR_MET_HUMAN TYR 6.9e-92 313.9 2 260 259 1221 1222 1223 1225 1227 1110 1127 1131 1201 1203 1202 1204 1265 1253 1248 1247 1246 1245 1244 1243 1242 1158 Hepatocyte growth factor receptor

Ligand: I90

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name