Ligand: HRM

Total number of chains: 5
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 5Y86A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC DYRK1A DYR1A_HUMAN 3ANRA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HRM Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 3ANRB 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi HRM Type1 133 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 3ANRC 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi HRM Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 3ANRD 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi HRM Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK3 DYRK3_HUMAN 5Y86A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HRM Type1 138 - 532 0 SEP350,PTR369,SEP445,TPO512 None Dual specificity tyrosine-phosphorylation-regulated kinase 3

Ligand: HRM

Total number of chains: 5
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 5Y86A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC DYRK1A DYR1A_HUMAN 3ANRA 2.6 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HRM Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
CMGC DYRK1A DYR1A_HUMAN 3ANRB 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iioi HRM Type1 133 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
CMGC DYRK1A DYR1A_HUMAN 3ANRC 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi HRM Type1 134 - 481 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
CMGC DYRK1A DYR1A_HUMAN 3ANRD 2.6 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oioi HRM Type1 134 - 479 0 PTR321 None Dual specificity tyrosine-phosphorylation-regulated kinase 1A Homo sapiens
CMGC DYRK3 DYRK3_HUMAN 5Y86A 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii HRM Type1 138 - 532 0 SEP350,PTR369,SEP445,TPO512 None Dual specificity tyrosine-phosphorylation-regulated kinase 3 Homo sapiens

Ligand: HRM

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism