Ligand: GYQ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6HZUB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 6HZUA P23458 854 1154 1154.0 GYQ:61201 Type1 Inactive DFGin 6.4583 13.248 ABAminus -115.79, 10.1 -155.61, 143.2 -135.89, 34.69 298.64, 85.33 -68.92, -23.66 in-in in 7.8907 Saltbr-in 2.6049 HRD-in -70.11, -45.53 64.37, 7.1 in-in-out SNCiio in-out ActLoopNT-in 2.7677 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -94.73, 34.76 APE9-dihe-in -73.48, 139.36 APE8-dihe-in -81.86, 74.79 APE8-rot-na 30.37 APE67-dihe-in -72.43, -9.67 -55.59, -34.31 APE12-dist-na 10.9672 APE11-dist-na 13.1742 APE10-dist-na 9.8871 APE9-dist-in 6.8026 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.2 0.204 0.265 A 302.0 293.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 6hzu TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6HZUB P23458 865 1154 1154.0 GYQ:61201 Type1 Inactive DFGin 6.4433 13.2473 ABAminus -119.96, 0.48 -155.13, 140.72 -132.65, 33.96 299.27, 84.27 -60.17, -34.27 in-in in 8.0228 Saltbr-in 2.7023 HRD-in -82.42, -47.78 71.93, 4.63 in-in-out SNCiio in-out ActLoopNT-in 2.9233 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -93.89, 29.59 APE9-dihe-in -63.03, 138.85 APE8-dihe-in -81.19, 78.97 APE8-rot-na 31.69 APE67-dihe-in -73.96, -7.04 -62.12, -30.09 APE12-dist-na 11.006 APE11-dist-na 13.2245 APE10-dist-na 9.8851 APE9-dist-in 6.6567 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.2 0.204 0.265 B 302.0 285.0 5 31 31 0 [[583, 847], [875, 1151]] 2.0 6hzu TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

Ligand: GYQ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6HZUB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 6HZUA P23458 854 1154 1154.0 GYQ:61201 Type1 Inactive DFGin 6.4583 13.248 ABAminus -115.79, 10.1 -155.61, 143.2 -135.89, 34.69 298.64, 85.33 -68.92, -23.66 in-in in 7.8907 Saltbr-in 2.6049 HRD-in -70.11, -45.53 64.37, 7.1 in-in-out SNCiio in-out ActLoopNT-in 2.7677 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -94.73, 34.76 APE9-dihe-in -73.48, 139.36 APE8-dihe-in -81.86, 74.79 APE8-rot-na 30.37 APE67-dihe-in -72.43, -9.67 -55.59, -34.31 APE12-dist-na 10.9672 APE11-dist-na 13.1742 APE10-dist-na 9.8871 APE9-dist-in 6.8026 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.2 0.204 0.265 A 302.0 293.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 6hzu Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 6HZUB P23458 865 1154 1154.0 GYQ:61201 Type1 Inactive DFGin 6.4433 13.2473 ABAminus -119.96, 0.48 -155.13, 140.72 -132.65, 33.96 299.27, 84.27 -60.17, -34.27 in-in in 8.0228 Saltbr-in 2.7023 HRD-in -82.42, -47.78 71.93, 4.63 in-in-out SNCiio in-out ActLoopNT-in 2.9233 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -93.89, 29.59 APE9-dihe-in -63.03, 138.85 APE8-dihe-in -81.19, 78.97 APE8-rot-na 31.69 APE67-dihe-in -73.96, -7.04 -62.12, -30.09 APE12-dist-na 11.006 APE11-dist-na 13.2245 APE10-dist-na 9.8851 APE9-dist-in 6.6567 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.2 0.204 0.265 B 302.0 285.0 5 31 31 0 [[583, 847], [875, 1151]] 2.0 6hzu Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

Ligand: GYQ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name