Ligand: GVP

Total number of chains: 1
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 2UW9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC AKT2 AKT2_HUMAN 2UW9A P31751 146 477 481.0 GVP:61480 Type1 Active DFGin 6.6921 13.4876 BLAminus -123.19, 167.76 65.45, 89.41 -103.32, 13.56 294.7, 84.5 -64.67, -30.65 in-in in 8.9152 Saltbr-in 3.4846 HRD-in -78.9, -54.33 80.74, -7.46 in-in-in SNCiii in-in ActLoopNT-in 2.8896 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.24, 166.16 APE9-dihe-na 136.4, -140.08 APE8-dihe-in -134.83, 122.5 APE8-rot-in 314.64 APE67-dihe-in -71.56, -23.74 -40.7, -46.8 APE12-dist-in 8.1712 APE11-dist-in 11.4277 APE10-dist-in 5.9073 APE9-dist-in 3.8771 None TPO309 TPO309 XRAY 2.1 0.226 0.305 A 342.0 312.0 0 28 28 0 [[152, 409]] 1.0 2uw9 AGC_AKT2_HUMAN AGC 1.8e-99 338.0 1.0 260.0 260.0 292 293 294 296 298 181 200 204 272 274 273 275.0 332 320 315 314 313 312 311 310 309 230 RAC-beta serine/threonine-protein kinase

Ligand: GVP

Total number of chains: 2
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2UW7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_BOVIN 2UW7A P00517 15 351 351.0 GVP:61351 Type1 Active DFGin 6.6166 13.7352 BLAminus -136.69, 175.22 59.69, 95.21 -111.12, 31.03 278.38, 57.43 -58.09, -25.49 in-in in 8.5612 Saltbr-in 2.7092 HRD-in -86.23, -51.08 72.7, 10.78 in-in-in SNCiii in-in ActLoopNT-in 3.0203 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -151.27, 162.23 APE9-dihe-na 121.1, -162.52 APE8-dihe-in -116.53, 136.36 APE8-rot-in 303.46 APE67-dihe-in -55.18, -28.45 -48.94, -51.5 APE12-dist-in 7.93 APE11-dist-in 11.4491 APE10-dist-in 5.8017 APE9-dist-in 3.5143 V105T,V124A,L174M,Q182K TPO198,SEP339 TPO198,SEP339 XRAY 2.1 0.239 0.318 A 351.0 337.0 0 25 25 0 [[44, 298]] 1.0 2uw7 Bos taurus AGC_PRKACA_BOVIN AGC 4.5e-94 320.4 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
AGC AKT2 AKT2_HUMAN 2UW9A P31751 146 477 481.0 GVP:61480 Type1 Active DFGin 6.6921 13.4876 BLAminus -123.19, 167.76 65.45, 89.41 -103.32, 13.56 294.7, 84.5 -64.67, -30.65 in-in in 8.9152 Saltbr-in 3.4846 HRD-in -78.9, -54.33 80.74, -7.46 in-in-in SNCiii in-in ActLoopNT-in 2.8896 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -160.24, 166.16 APE9-dihe-na 136.4, -140.08 APE8-dihe-in -134.83, 122.5 APE8-rot-in 314.64 APE67-dihe-in -71.56, -23.74 -40.7, -46.8 APE12-dist-in 8.1712 APE11-dist-in 11.4277 APE10-dist-in 5.9073 APE9-dist-in 3.8771 None TPO309 TPO309 XRAY 2.1 0.226 0.305 A 342.0 312.0 0 28 28 0 [[152, 409]] 1.0 2uw9 Homo sapiens AGC_AKT2_HUMAN AGC 1.8e-99 338.0 1.0 260.0 260.0 292 293 294 296 298 181 200 204 272 274 273 275.0 332 320 315 314 313 312 311 310 309 230 RAC-beta serine/threonine-protein kinase

Ligand: GVP

Total number of chains: 1
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 2UW7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_BOVIN 2UW7A P00517 15 351 351.0 GVP:61351 Type1 Active DFGin 6.6166 13.7352 BLAminus -136.69, 175.22 59.69, 95.21 -111.12, 31.03 278.38, 57.43 -58.09, -25.49 in-in in 8.5612 Saltbr-in 2.7092 HRD-in -86.23, -51.08 72.7, 10.78 in-in-in SNCiii in-in ActLoopNT-in 3.0203 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -151.27, 162.23 APE9-dihe-na 121.1, -162.52 APE8-dihe-in -116.53, 136.36 APE8-rot-in 303.46 APE67-dihe-in -55.18, -28.45 -48.94, -51.5 APE12-dist-in 7.93 APE11-dist-in 11.4491 APE10-dist-in 5.8017 APE9-dist-in 3.5143 V105T,V124A,L174M,Q182K TPO198,SEP339 TPO198,SEP339 XRAY 2.1 0.239 0.318 A 351.0 337.0 0 25 25 0 [[44, 298]] 1.0 2uw7 Bos taurus AGC_PRKACA_BOVIN AGC 4.5e-94 320.4 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha