Ligand: GUI

Total number of chains: 4
Active chains: 2
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 75.0% 5JZNA
DFGin ABAminus 1 25.0% 2XB7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK DCLK1 DCLK1_HUMAN 5JZNA O15075 379 648 740.0 GUI:701 Type1 Active DFGin 6.4045 14.509 BLAminus -125.42, -165.27 48.91, 82.22 -91.62, 28.76 281.24, 72.51 -61.94, -30.05 in-in in 8.9725 Saltbr-in 3.0956 HRD-in -79.96, -46.23 67.3, 2.72 in-in-in SNCiii in-in ActLoopNT-in 2.8538 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.84, 160.64 APE9-dihe-na 123.28, -170.71 APE8-dihe-in -105.56, 128.85 APE8-rot-in 303.98 APE67-dihe-in -62.18, -35.69 -48.05, -41.12 APE12-dist-in 8.8731 APE11-dist-in 12.173 APE10-dist-in 6.6488 APE9-dist-in 4.2826 None None None XRAY 2.85 0.183 0.225 A 280.0 268.0 2 25 25 0 [[390, 647]] 1.0 5jzn CAMK_DCLK1_HUMAN CAMK 6.1e-90 306.9 1.0 256.0 256.0 532 533 534 536 538 419 436 440 508 510 509 511.0 569 557 552 551 550 549 548 547 546 466 Serine/threonine-protein kinase DCLK1
CAMK DCLK1 DCLK1_HUMAN 5JZNB O15075 380 648 740.0 GUI:701 Type1 Active DFGin 6.649 14.7365 BLAminus -125.38, -165.81 48.37, 82.76 -91.87, 28.76 282.5, 73.21 -61.79, -29.61 in-in in 9.1429 Saltbr-in 3.0461 HRD-in -80.35, -46.23 67.17, 3.18 in-in-in SNCiii in-in ActLoopNT-in 2.9507 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.87, 160.33 APE9-dihe-na 123.29, -171.62 APE8-dihe-in -106.44, 128.21 APE8-rot-in 306.11 APE67-dihe-in -61.96, -35.8 -48.32, -41.43 APE12-dist-in 9.0872 APE11-dist-in 12.317 APE10-dist-in 6.8543 APE9-dist-in 4.3214 None None None XRAY 2.85 0.183 0.225 B 280.0 266.0 3 25 25 0 [[390, 647]] 1.0 5jzn CAMK_DCLK1_HUMAN CAMK 6.1e-90 306.9 1.0 256.0 256.0 532 533 534 536 538 419 436 440 508 510 509 511.0 569 557 552 551 550 549 548 547 546 466 Serine/threonine-protein kinase DCLK1
TYR ALK ALK_HUMAN 2XB7A Q9UM73 1095 1401 1620.0 GUI:1501 Type1 Inactive DFGin 5.7305 14.5992 ABAminus -132.42, -0.18 -141.44, 142.16 -131.03, 43.77 292.96, 89.17 -72.28, -38.54 in-in in 7.5319 Saltbr-in 3.1842 HRD-in -87.04, -46.67 85.76, -13.12 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -99.32, -3.08 APE9-dihe-in -73.74, 136.06 APE8-dihe-in -78.24, 56.9 APE8-rot-na 30.55 APE67-dihe-in -70.57, -6.09 -40.69, -40.8 APE12-dist-na 999.0 APE11-dist-na 15.2726 APE10-dist-na 10.496 APE9-dist-out 8.3356 None None None XRAY 2.5 0.195 0.243 A 315.0 286.0 21 30 16 14 [[1116, 1385]] 1.0 2xb7 TYR_ALK_HUMAN TYR 1.2e-90 309.3 1.0 260.0 260.0 1269 1270 1271 1273 1275 1150 1167 1171 1246 1248 1247 1249.0 1311 1299 1294 1293 1292 1291 1290 1289 1288 1197 ALK tyrosine kinase receptor
TYR FES FES_HUMAN 4E93A P07332 448 822 822.0 GUI:60901 Type1 None DFGin 7.2393 15.2064 BLAminus -147.07, -173.8 68.79, 70.92 -92.31, 15.15 286.08, 92.67 -61.32, -36.23 in-in in 8.1557 Saltbr-in 2.8146 HRD-in -75.42, -47.46 72.8, -15.51 in-in-none SNCiin in-none ActLoopNT-in 2.8988 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -46.55 APE8-dihe-in -81.8, 74.32 APE8-rot-na 28.54 APE67-dihe-in -65.5, -10.65 -48.91, -48.38 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.5764 None None None XRAY 1.84 0.189 0.238 A 377.0 359.0 14 30 16 14 [[561, 816]] 1.0 4e93 TYR_FES_HUMAN TYR 6.6e-94 320.0 1.0 260.0 260.0 700 701 702 704 706 590 607 611 680 682 681 683.0 742 730 725 724 723 722 721 720 719 637 Tyrosine-protein kinase Fes/Fps

Ligand: GUI

Total number of chains: 4
Active chains: 2
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 75.0% 5JZNA
DFGin ABAminus 1 25.0% 2XB7A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK DCLK1 DCLK1_HUMAN 5JZNA O15075 379 648 740.0 GUI:701 Type1 Active DFGin 6.4045 14.509 BLAminus -125.42, -165.27 48.91, 82.22 -91.62, 28.76 281.24, 72.51 -61.94, -30.05 in-in in 8.9725 Saltbr-in 3.0956 HRD-in -79.96, -46.23 67.3, 2.72 in-in-in SNCiii in-in ActLoopNT-in 2.8538 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.84, 160.64 APE9-dihe-na 123.28, -170.71 APE8-dihe-in -105.56, 128.85 APE8-rot-in 303.98 APE67-dihe-in -62.18, -35.69 -48.05, -41.12 APE12-dist-in 8.8731 APE11-dist-in 12.173 APE10-dist-in 6.6488 APE9-dist-in 4.2826 None None None XRAY 2.85 0.183 0.225 A 280.0 268.0 2 25 25 0 [[390, 647]] 1.0 5jzn Homo sapiens CAMK_DCLK1_HUMAN CAMK 6.1e-90 306.9 1.0 256.0 256.0 532 533 534 536 538 419 436 440 508 510 509 511.0 569 557 552 551 550 549 548 547 546 466 Serine/threonine-protein kinase DCLK1
CAMK DCLK1 DCLK1_HUMAN 5JZNB O15075 380 648 740.0 GUI:701 Type1 Active DFGin 6.649 14.7365 BLAminus -125.38, -165.81 48.37, 82.76 -91.87, 28.76 282.5, 73.21 -61.79, -29.61 in-in in 9.1429 Saltbr-in 3.0461 HRD-in -80.35, -46.23 67.17, 3.18 in-in-in SNCiii in-in ActLoopNT-in 2.9507 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.87, 160.33 APE9-dihe-na 123.29, -171.62 APE8-dihe-in -106.44, 128.21 APE8-rot-in 306.11 APE67-dihe-in -61.96, -35.8 -48.32, -41.43 APE12-dist-in 9.0872 APE11-dist-in 12.317 APE10-dist-in 6.8543 APE9-dist-in 4.3214 None None None XRAY 2.85 0.183 0.225 B 280.0 266.0 3 25 25 0 [[390, 647]] 1.0 5jzn Homo sapiens CAMK_DCLK1_HUMAN CAMK 6.1e-90 306.9 1.0 256.0 256.0 532 533 534 536 538 419 436 440 508 510 509 511.0 569 557 552 551 550 549 548 547 546 466 Serine/threonine-protein kinase DCLK1
TYR ALK ALK_HUMAN 2XB7A Q9UM73 1095 1401 1620.0 GUI:1501 Type1 Inactive DFGin 5.7305 14.5992 ABAminus -132.42, -0.18 -141.44, 142.16 -131.03, 43.77 292.96, 89.17 -72.28, -38.54 in-in in 7.5319 Saltbr-in 3.1842 HRD-in -87.04, -46.67 85.76, -13.12 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -99.32, -3.08 APE9-dihe-in -73.74, 136.06 APE8-dihe-in -78.24, 56.9 APE8-rot-na 30.55 APE67-dihe-in -70.57, -6.09 -40.69, -40.8 APE12-dist-na 999.0 APE11-dist-na 15.2726 APE10-dist-na 10.496 APE9-dist-out 8.3356 None None None XRAY 2.5 0.195 0.243 A 315.0 286.0 21 30 16 14 [[1116, 1385]] 1.0 2xb7 Homo sapiens TYR_ALK_HUMAN TYR 1.2e-90 309.3 1.0 260.0 260.0 1269 1270 1271 1273 1275 1150 1167 1171 1246 1248 1247 1249.0 1311 1299 1294 1293 1292 1291 1290 1289 1288 1197 ALK tyrosine kinase receptor
TYR FES FES_HUMAN 4E93A P07332 448 822 822.0 GUI:60901 Type1 None DFGin 7.2393 15.2064 BLAminus -147.07, -173.8 68.79, 70.92 -92.31, 15.15 286.08, 92.67 -61.32, -36.23 in-in in 8.1557 Saltbr-in 2.8146 HRD-in -75.42, -47.46 72.8, -15.51 in-in-none SNCiin in-none ActLoopNT-in 2.8988 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -46.55 APE8-dihe-in -81.8, 74.32 APE8-rot-na 28.54 APE67-dihe-in -65.5, -10.65 -48.91, -48.38 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.5764 None None None XRAY 1.84 0.189 0.238 A 377.0 359.0 14 30 16 14 [[561, 816]] 1.0 4e93 Homo sapiens TYR_FES_HUMAN TYR 6.6e-94 320.0 1.0 260.0 260.0 700 701 702 704 706 590 607 611 680 682 681 683.0 742 730 725 724 723 722 721 720 719 637 Tyrosine-protein kinase Fes/Fps

Ligand: GUI

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name