Ligand: GUI

Total number of chains: 4
Active chains: 2
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 75.0% 5JZNA
DFGin ABAminus 1 25.0% 2XB7A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK DCLK1 DCLK1_HUMAN 5JZNA O15075 379 648 740.0 GUI:701 Type1 Active DFGin 6.404 14.509 BLAminus -125.42, -165.27 48.91, 82.22 -91.62, 28.76 281.24, 72.51 -61.94, -30.05 in-in in 8.973 Saltbr-in 3.096 HRD-in -79.96, -46.23 67.3, 2.72 in-in-in SNCiii in-in ActLoopNT-in 2.854 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.84, 160.64 APE9-dihe-na 123.28, -170.71 APE8-dihe-in -105.56, 128.85 APE8-rot-in 303.98 APE67-dihe-in -62.18, -35.69 -48.05, -41.12 APE12-dist-in 8.873 APE11-dist-in 12.173 APE10-dist-in 6.649 APE9-dist-in 4.283 None None None XRAY 2.85 0.183 0.225 A 280 268 2 0 0 0 [[390, 647]] 1.0 5jzn CAMK_DCLK1_HUMAN CAMK 6.1e-90 306.9 1 256 256 532 533 534 536 538 419 436 440 508 510 509 511 569 557 552 551 550 549 548 547 546 466 Serine/threonine-protein kinase DCLK1
CAMK DCLK1 DCLK1_HUMAN 5JZNB O15075 380 648 740.0 GUI:701 Type1 Active DFGin 6.649 14.736 BLAminus -125.38, -165.81 48.37, 82.76 -91.87, 28.76 282.5, 73.21 -61.79, -29.61 in-in in 9.143 Saltbr-in 3.046 HRD-in -80.35, -46.23 67.17, 3.18 in-in-in SNCiii in-in ActLoopNT-in 2.951 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.87, 160.33 APE9-dihe-na 123.29, -171.62 APE8-dihe-in -106.44, 128.21 APE8-rot-in 306.11 APE67-dihe-in -61.96, -35.8 -48.32, -41.43 APE12-dist-in 9.087 APE11-dist-in 12.317 APE10-dist-in 6.854 APE9-dist-in 4.321 None None None XRAY 2.85 0.183 0.225 B 280 266 3 0 0 0 [[390, 647]] 1.0 5jzn CAMK_DCLK1_HUMAN CAMK 6.1e-90 306.9 1 256 256 532 533 534 536 538 419 436 440 508 510 509 511 569 557 552 551 550 549 548 547 546 466 Serine/threonine-protein kinase DCLK1
TYR ALK ALK_HUMAN 2XB7A Q9UM73 1095 1401 1620.0 GUI:1501 Type1 Inactive DFGin 5.731 14.599 ABAminus -132.42, -0.18 -141.44, 142.16 -131.03, 43.77 292.96, 89.17 -72.28, -38.54 in-in in 7.532 Saltbr-in 3.184 HRD-in -87.04, -46.67 85.76, -13.12 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -99.32, -3.08 APE9-dihe-in -73.74, 136.06 APE8-dihe-in -78.24, 56.9 APE8-rot-na 30.55 APE67-dihe-in -70.57, -6.09 -40.69, -40.8 APE12-dist-na 999.0 APE11-dist-na 15.273 APE10-dist-na 10.496 APE9-dist-out 8.336 None None None XRAY 2.5 0.195 0.243 A 315 286 21 0 0 14 [[1116, 1385]] 1.0 2xb7 TYR_ALK_HUMAN TYR 1.2e-90 309.3 1 260 260 1269 1270 1271 1273 1275 1150 1167 1171 1246 1248 1247 1249 1311 1299 1294 1293 1292 1291 1290 1289 1288 1197 ALK tyrosine kinase receptor
TYR FES FES_HUMAN 4E93A P07332 448 822 822.0 GUI:60901 Type1 None DFGin 7.239 15.206 BLAminus -147.07, -173.8 68.79, 70.92 -92.31, 15.15 286.08, 92.67 -61.32, -36.23 in-in in 8.156 Saltbr-in 2.815 HRD-in -75.42, -47.46 72.8, -15.51 in-in-none SNCiin in-none ActLoopNT-in 2.899 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -46.55 APE8-dihe-in -81.8, 74.32 APE8-rot-na 28.54 APE67-dihe-in -65.5, -10.65 -48.91, -48.38 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.576 None None None XRAY 1.84 0.189 0.238 A 377 359 14 0 0 14 [[561, 816]] 1.0 4e93 TYR_FES_HUMAN TYR 6.6e-94 320.0 1 260 260 700 701 702 704 706 590 607 611 680 682 681 683 742 730 725 724 723 722 721 720 719 637 Tyrosine-protein kinase Fes/Fps

Ligand: GUI

Total number of chains: 4
Active chains: 2
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 75.0% 5JZNA
DFGin ABAminus 1 25.0% 2XB7A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK DCLK1 DCLK1_HUMAN 5JZNA O15075 379 648 740.0 GUI:701 Type1 Active DFGin 6.404 14.509 BLAminus -125.42, -165.27 48.91, 82.22 -91.62, 28.76 281.24, 72.51 -61.94, -30.05 in-in in 8.973 Saltbr-in 3.096 HRD-in -79.96, -46.23 67.3, 2.72 in-in-in SNCiii in-in ActLoopNT-in 2.854 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.84, 160.64 APE9-dihe-na 123.28, -170.71 APE8-dihe-in -105.56, 128.85 APE8-rot-in 303.98 APE67-dihe-in -62.18, -35.69 -48.05, -41.12 APE12-dist-in 8.873 APE11-dist-in 12.173 APE10-dist-in 6.649 APE9-dist-in 4.283 None None None XRAY 2.85 0.183 0.225 A 280 268 2 0 0 0 [[390, 647]] 1.0 5jzn Homo sapiens CAMK_DCLK1_HUMAN CAMK 6.1e-90 306.9 1 256 256 532 533 534 536 538 419 436 440 508 510 509 511 569 557 552 551 550 549 548 547 546 466 Serine/threonine-protein kinase DCLK1
CAMK DCLK1 DCLK1_HUMAN 5JZNB O15075 380 648 740.0 GUI:701 Type1 Active DFGin 6.649 14.736 BLAminus -125.38, -165.81 48.37, 82.76 -91.87, 28.76 282.5, 73.21 -61.79, -29.61 in-in in 9.143 Saltbr-in 3.046 HRD-in -80.35, -46.23 67.17, 3.18 in-in-in SNCiii in-in ActLoopNT-in 2.951 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -155.87, 160.33 APE9-dihe-na 123.29, -171.62 APE8-dihe-in -106.44, 128.21 APE8-rot-in 306.11 APE67-dihe-in -61.96, -35.8 -48.32, -41.43 APE12-dist-in 9.087 APE11-dist-in 12.317 APE10-dist-in 6.854 APE9-dist-in 4.321 None None None XRAY 2.85 0.183 0.225 B 280 266 3 0 0 0 [[390, 647]] 1.0 5jzn Homo sapiens CAMK_DCLK1_HUMAN CAMK 6.1e-90 306.9 1 256 256 532 533 534 536 538 419 436 440 508 510 509 511 569 557 552 551 550 549 548 547 546 466 Serine/threonine-protein kinase DCLK1
TYR ALK ALK_HUMAN 2XB7A Q9UM73 1095 1401 1620.0 GUI:1501 Type1 Inactive DFGin 5.731 14.599 ABAminus -132.42, -0.18 -141.44, 142.16 -131.03, 43.77 292.96, 89.17 -72.28, -38.54 in-in in 7.532 Saltbr-in 3.184 HRD-in -87.04, -46.67 85.76, -13.12 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -99.32, -3.08 APE9-dihe-in -73.74, 136.06 APE8-dihe-in -78.24, 56.9 APE8-rot-na 30.55 APE67-dihe-in -70.57, -6.09 -40.69, -40.8 APE12-dist-na 999.0 APE11-dist-na 15.273 APE10-dist-na 10.496 APE9-dist-out 8.336 None None None XRAY 2.5 0.195 0.243 A 315 286 21 0 0 14 [[1116, 1385]] 1.0 2xb7 Homo sapiens TYR_ALK_HUMAN TYR 1.2e-90 309.3 1 260 260 1269 1270 1271 1273 1275 1150 1167 1171 1246 1248 1247 1249 1311 1299 1294 1293 1292 1291 1290 1289 1288 1197 ALK tyrosine kinase receptor
TYR FES FES_HUMAN 4E93A P07332 448 822 822.0 GUI:60901 Type1 None DFGin 7.239 15.206 BLAminus -147.07, -173.8 68.79, 70.92 -92.31, 15.15 286.08, 92.67 -61.32, -36.23 in-in in 8.156 Saltbr-in 2.815 HRD-in -75.42, -47.46 72.8, -15.51 in-in-none SNCiin in-none ActLoopNT-in 2.899 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -46.55 APE8-dihe-in -81.8, 74.32 APE8-rot-na 28.54 APE67-dihe-in -65.5, -10.65 -48.91, -48.38 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.576 None None None XRAY 1.84 0.189 0.238 A 377 359 14 0 0 14 [[561, 816]] 1.0 4e93 Homo sapiens TYR_FES_HUMAN TYR 6.6e-94 320.0 1 260 260 700 701 702 704 706 590 607 611 680 682 681 683 742 730 725 724 723 722 721 720 719 637 Tyrosine-protein kinase Fes/Fps

Ligand: GUI

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name