Ligand: GAB

Total number of chains: 1
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 5CSVA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CSNK2A1 CSK21_HUMAN 5CSVA P68400 3 329 391.0 GAB:403 Type1 Active DFGin 7.3818 16.0985 BLAminus -118.79, -177.45 53.09, 78.38 -90.87, 18.49 297.16, 78.66 -68.05, -20.99 in-in in 9.1427 Saltbr-in 2.7754 HRD-in -72.57, -49.26 69.56, 13.18 in-in-in SNCiii in-in ActLoopNT-in 2.8617 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.04, 168.19 APE9-dihe-na 62.37, 162.1 APE8-dihe-in -85.46, 146.49 APE8-rot-in 294.48 APE67-dihe-in -70.74, -13.55 -37.24, -54.74 APE12-dist-in 12.5937 APE11-dist-in 10.2091 APE10-dist-in 6.1376 APE9-dist-in 3.2142 R21S,K74A,K75A,K76A None None XRAY 1.375 0.18 0.195 A 328.0 327.0 0 27 27 0 [[39, 324]] 1.0 5csv CMGC_CSNK2A1_HUMAN CMGC 8.1e-69 238.0 1.0 301.0 301.0 174 175 176 178 180 68 81 85 153 155 154 156.0 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha

Ligand: GAB

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5CSVA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_CRIGR 6SPUA P25321 14 351 351.0 GAB:60405 Type1 Inactive DFGin 6.3931 14.5224 BLAminus -124.88, 173.78 70.46, 84.77 -97.04, 23.36 270.78, 58.59 -61.61, -26.89 in-in in 8.6469 Saltbr-in 2.7353 HRD-in -87.8, -49.67 67.09, 13.22 in-in-out SNCiio in-out ActLoopNT-in 2.9411 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -160.63, 160.29 APE9-dihe-na 125.51, -175.3 APE8-dihe-in -107.62, 144.0 APE8-rot-out 190.74 APE67-dihe-in -65.31, -18.62 -49.85, -47.63 APE12-dist-in 8.0401 APE11-dist-in 11.2233 APE10-dist-in 5.7335 APE9-dist-in 3.8932 None SEP140,TPO198,SEP339 SEP140,TPO198,SEP339 XRAY 1.39 0.165 0.184 A 353.0 338.0 0 25 25 0 [[44, 298]] 1.0 6spu Cricetulus griseus AGC_PRKACA_CRIGR AGC 6.6e-95 323.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha
CMGC CSNK2A1 CSK21_HUMAN 5CSVA P68400 3 329 391.0 GAB:403 Type1 Active DFGin 7.3818 16.0985 BLAminus -118.79, -177.45 53.09, 78.38 -90.87, 18.49 297.16, 78.66 -68.05, -20.99 in-in in 9.1427 Saltbr-in 2.7754 HRD-in -72.57, -49.26 69.56, 13.18 in-in-in SNCiii in-in ActLoopNT-in 2.8617 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.04, 168.19 APE9-dihe-na 62.37, 162.1 APE8-dihe-in -85.46, 146.49 APE8-rot-in 294.48 APE67-dihe-in -70.74, -13.55 -37.24, -54.74 APE12-dist-in 12.5937 APE11-dist-in 10.2091 APE10-dist-in 6.1376 APE9-dist-in 3.2142 R21S,K74A,K75A,K76A None None XRAY 1.375 0.18 0.195 A 328.0 327.0 0 27 27 0 [[39, 324]] 1.0 5csv Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 8.1e-69 238.0 1.0 301.0 301.0 174 175 176 178 180 68 81 85 153 155 154 156.0 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha

Ligand: GAB

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 6SPUA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC PRKACA KAPCA_CRIGR 6SPUA P25321 14 351 351.0 GAB:60405 Type1 Inactive DFGin 6.3931 14.5224 BLAminus -124.88, 173.78 70.46, 84.77 -97.04, 23.36 270.78, 58.59 -61.61, -26.89 in-in in 8.6469 Saltbr-in 2.7353 HRD-in -87.8, -49.67 67.09, 13.22 in-in-out SNCiio in-out ActLoopNT-in 2.9411 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -160.63, 160.29 APE9-dihe-na 125.51, -175.3 APE8-dihe-in -107.62, 144.0 APE8-rot-out 190.74 APE67-dihe-in -65.31, -18.62 -49.85, -47.63 APE12-dist-in 8.0401 APE11-dist-in 11.2233 APE10-dist-in 5.7335 APE9-dist-in 3.8932 None SEP140,TPO198,SEP339 SEP140,TPO198,SEP339 XRAY 1.39 0.165 0.184 A 353.0 338.0 0 25 25 0 [[44, 298]] 1.0 6spu Cricetulus griseus AGC_PRKACA_CRIGR AGC 6.6e-95 323.2 1.0 260.0 260.0 184 185 186 188 190 73 92 96 164 166 165 167.0 221 209 204 203 202 201 200 199 198 122 cAMP-dependent protein kinase catalytic subunit alpha