Ligand: FC8

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 6GU4A
None None 1 50.0% 6GUKA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK1 CDK1_HUMAN 6GU4A P06493 1 289 297.0 FC8:60301 Type1 Inactive DFGin 7.5811 14.5839 BLAminus -145.61, 170.8 53.63, 78.2 -92.59, 26.44 286.38, 84.12 -71.67, -17.29 in-in in 8.9628 Saltbr-in 2.8331 HRD-in -78.07, -55.7 69.57, -1.83 in-in-out SNCiio in-out ActLoopNT-in 2.8069 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiio APE10-dihe-na -51.9, 100.35 APE9-dihe-na -20.85, -56.41 APE8-dihe-in -125.37, 142.85 APE8-rot-out 188.74 APE67-dihe-in -66.53, -22.83 -106.3, -18.52 APE12-dist-in 13.7675 APE11-dist-in 10.879 APE10-dist-in 7.8762 APE9-dist-out 10.1528 None None None XRAY 2.73 0.199 0.253 A 302.0 289.0 0 28 28 0 [[4, 287]] 1.0 6gu4 CMGC_CDK1_HUMAN CMGC 2.7e-87 298.9 1.0 301.0 301.0 145 146 147 149 151 33 51 55 125 127 126 128.0 186 173 168 167 166 165 164 163 162 81 Cyclin-dependent kinase 1
CMGC CDK2 CDK2_HUMAN 6GUKA P24941 1 298 298.0 FC8:301 Type1 Inactive None 11.4951 18.2957 None -105.76, 142.13 85.41, 11.26 -53.22, 139.96 258.83, 85.48 82.71, -9.99 out-out out 16.2084 Saltbr-out 15.8102 HRD-in -84.25, -64.23 86.29, -13.89 out-out-out SNCooo out-out ActLoopNT-out 5.7839 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 126.62 APE8-dihe-in -72.63, 127.56 APE8-rot-out 192.14 APE67-dihe-in -62.77, -24.98 -100.92, -3.58 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.2128 None None None XRAY 1.3 0.206 0.232 A 306.0 278.0 20 28 18 10 [[4, 286]] 1.0 6guk CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: FC8

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 6GU4A
None None 1 50.0% 6GUKA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK1 CDK1_HUMAN 6GU4A P06493 1 289 297.0 FC8:60301 Type1 Inactive DFGin 7.5811 14.5839 BLAminus -145.61, 170.8 53.63, 78.2 -92.59, 26.44 286.38, 84.12 -71.67, -17.29 in-in in 8.9628 Saltbr-in 2.8331 HRD-in -78.07, -55.7 69.57, -1.83 in-in-out SNCiio in-out ActLoopNT-in 2.8069 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiio APE10-dihe-na -51.9, 100.35 APE9-dihe-na -20.85, -56.41 APE8-dihe-in -125.37, 142.85 APE8-rot-out 188.74 APE67-dihe-in -66.53, -22.83 -106.3, -18.52 APE12-dist-in 13.7675 APE11-dist-in 10.879 APE10-dist-in 7.8762 APE9-dist-out 10.1528 None None None XRAY 2.73 0.199 0.253 A 302.0 289.0 0 28 28 0 [[4, 287]] 1.0 6gu4 Homo sapiens CMGC_CDK1_HUMAN CMGC 2.7e-87 298.9 1.0 301.0 301.0 145 146 147 149 151 33 51 55 125 127 126 128.0 186 173 168 167 166 165 164 163 162 81 Cyclin-dependent kinase 1
CMGC CDK2 CDK2_HUMAN 6GUKA P24941 1 298 298.0 FC8:301 Type1 Inactive None 11.4951 18.2957 None -105.76, 142.13 85.41, 11.26 -53.22, 139.96 258.83, 85.48 82.71, -9.99 out-out out 16.2084 Saltbr-out 15.8102 HRD-in -84.25, -64.23 86.29, -13.89 out-out-out SNCooo out-out ActLoopNT-out 5.7839 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 126.62 APE8-dihe-in -72.63, 127.56 APE8-rot-out 192.14 APE67-dihe-in -62.77, -24.98 -100.92, -3.58 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.2128 None None None XRAY 1.3 0.206 0.232 A 306.0 278.0 20 28 18 10 [[4, 286]] 1.0 6guk Homo sapiens CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: FC8

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name