Ligand: F9J

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 3ZMMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 3ZMMA O60674 844 1130 1132.0 F9J:2133 Type1 Inactive DFGin 6.5652 13.9009 ABAminus -124.92, 4.32 -148.66, 145.32 -139.04, 35.94 291.38, 91.22 -76.64, -20.0 in-in in 8.4695 Saltbr-in 2.6263 HRD-in -74.41, -53.48 82.29, -12.58 in-in-none SNCiin in-none ActLoopNT-in 2.6904 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 144.54 APE9-dihe-in -152.47, 158.96 APE8-dihe-in -87.79, 67.39 APE8-rot-na 35.81 APE67-dihe-in -75.46, -0.84 -60.96, -24.67 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.3816 APE9-dist-in 7.793 K943A,K945A PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.51 0.195 0.246 A 298.0 275.0 12 31 27 4 [[545, 807], [849, 1125]] 2.0 3zmm TYR_JAK2-2_HUMAN TYR 1.1e-86 296.3 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3ZMMB O60674 843 1131 1132.0 F9J:2134 Type1 Inactive DFGin 6.5724 14.2219 ABAminus -118.91, 2.8 -144.65, 134.95 -129.24, 31.19 288.83, 86.73 -65.15, -32.55 in-in in 8.4936 Saltbr-in 2.6309 HRD-in -67.1, -39.55 67.31, -4.77 in-in-in SNCiii in-in ActLoopNT-in 2.8094 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -137.08, 109.88 APE9-dihe-in -113.35, 152.82 APE8-dihe-in -78.67, 75.19 APE8-rot-na 30.04 APE67-dihe-in -84.91, -6.79 -57.53, -23.83 APE12-dist-na 11.336 APE11-dist-na 11.9025 APE10-dist-na 12.1367 APE9-dist-in 7.6903 K943A,K945A PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.51 0.195 0.246 B 298.0 276.0 13 31 31 0 [[545, 807], [849, 1125]] 2.0 3zmm TYR_JAK2-2_HUMAN TYR 1.1e-86 296.3 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

Ligand: F9J

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 3ZMMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 3ZMMA O60674 844 1130 1132.0 F9J:2133 Type1 Inactive DFGin 6.5652 13.9009 ABAminus -124.92, 4.32 -148.66, 145.32 -139.04, 35.94 291.38, 91.22 -76.64, -20.0 in-in in 8.4695 Saltbr-in 2.6263 HRD-in -74.41, -53.48 82.29, -12.58 in-in-none SNCiin in-none ActLoopNT-in 2.6904 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 144.54 APE9-dihe-in -152.47, 158.96 APE8-dihe-in -87.79, 67.39 APE8-rot-na 35.81 APE67-dihe-in -75.46, -0.84 -60.96, -24.67 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.3816 APE9-dist-in 7.793 K943A,K945A PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.51 0.195 0.246 A 298.0 275.0 12 31 27 4 [[545, 807], [849, 1125]] 2.0 3zmm Homo sapiens TYR_JAK2-2_HUMAN TYR 1.1e-86 296.3 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3ZMMB O60674 843 1131 1132.0 F9J:2134 Type1 Inactive DFGin 6.5724 14.2219 ABAminus -118.91, 2.8 -144.65, 134.95 -129.24, 31.19 288.83, 86.73 -65.15, -32.55 in-in in 8.4936 Saltbr-in 2.6309 HRD-in -67.1, -39.55 67.31, -4.77 in-in-in SNCiii in-in ActLoopNT-in 2.8094 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -137.08, 109.88 APE9-dihe-in -113.35, 152.82 APE8-dihe-in -78.67, 75.19 APE8-rot-na 30.04 APE67-dihe-in -84.91, -6.79 -57.53, -23.83 APE12-dist-na 11.336 APE11-dist-na 11.9025 APE10-dist-na 12.1367 APE9-dist-in 7.6903 K943A,K945A PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.51 0.195 0.246 B 298.0 276.0 13 31 31 0 [[545, 807], [849, 1125]] 2.0 3zmm Homo sapiens TYR_JAK2-2_HUMAN TYR 1.1e-86 296.3 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

Ligand: F9J

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name