Ligand: F7D

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 6CMMD
None None 1 33.3% 6VXRA
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK MELK MELK_HUMAN 6VXRA Q14680 1 332 651.0 F7D:401 Type1 Inactive None 999.0 999.0 None -127.35, 176.73 71.93, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 out-none out 11.248 Saltbr-none 999.0 HRD-in -70.68, -53.91 75.77, 1.43 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, -30.71 APE9-dihe-na -63.58, -35.16 APE8-dihe-out -106.88, 12.59 APE8-rot-in 297.84 APE67-dihe-in -59.4, -25.09 -56.16, -41.18 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.034 None None None XRAY 2.1 0.221 0.248 A 339 309 23 0 0 18 [[11, 263]] 1.0 6vxr CAMK_MELK_HUMAN CAMK 1e-88 303.1 1 256 256 149 150 151 153 155 40 57 61 129 131 130 132 191 178 173 172 171 170 169 168 167 87 Maternal embryonic leucine zipper kinase
CK1 VRK1 VRK1_HUMAN 6CMMB Q99986 23 341 396.0 F7D:401 Type1 Inactive DFGin 8.476 14.483 BLAminus -115.06, 177.55 64.23, 84.91 -98.08, 23.22 291.58, 82.57 -66.41, -28.16 in-in in 7.601 Saltbr-in 2.897 HRD-in -88.21, -48.16 77.0, 4.0 in-in-out SNCiio in-out ActLoopNT-in 2.959 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -59.62, 146.4 APE9-dihe-na 107.7, -170.45 APE8-dihe-in -90.13, 117.89 APE8-rot-in 302.22 APE67-dihe-in -67.83, -25.02 -51.39, -42.58 APE12-dist-out 15.037 APE11-dist-in 13.451 APE10-dist-in 7.738 APE9-dist-in 4.065 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.1 0.192 0.222 B 364 310 9 0 0 0 [[37, 326]] 1.0 6cmm CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1 261 261 196 197 198 200 202 71 83 87 174 176 175 177 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CMMD Q99986 23 341 396.0 F7D:401 Type1 Inactive DFGin 8.303 14.576 BLAminus -120.35, -178.73 57.57, 80.72 -90.78, 22.63 288.79, 76.0 -64.84, -22.8 in-in in 7.794 Saltbr-in 2.995 HRD-in -88.03, -46.07 76.94, -0.28 in-in-out SNCiio in-out ActLoopNT-in 2.909 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -59.16, 154.16 APE9-dihe-na 94.99, -165.63 APE8-dihe-in -97.55, 123.52 APE8-rot-in 296.28 APE67-dihe-in -67.77, -24.35 -58.36, -42.41 APE12-dist-out 14.924 APE11-dist-in 13.193 APE10-dist-in 7.433 APE9-dist-in 4.166 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.1 0.192 0.222 D 364 315 4 0 0 0 [[37, 326]] 1.0 6cmm CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1 261 261 196 197 198 200 202 71 83 87 174 176 175 177 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1

Ligand: F7D

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 6CMMD
None None 1 33.3% 6VXRA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK MELK MELK_HUMAN 6VXRA Q14680 1 332 651.0 F7D:401 Type1 Inactive None 999.0 999.0 None -127.35, 176.73 71.93, 999.0 999.0, 999.0 999.0, 999.0 999.0, 999.0 out-none out 11.248 Saltbr-none 999.0 HRD-in -70.68, -53.91 75.77, 1.43 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, -30.71 APE9-dihe-na -63.58, -35.16 APE8-dihe-out -106.88, 12.59 APE8-rot-in 297.84 APE67-dihe-in -59.4, -25.09 -56.16, -41.18 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.034 None None None XRAY 2.1 0.221 0.248 A 339 309 23 0 0 18 [[11, 263]] 1.0 6vxr Homo sapiens CAMK_MELK_HUMAN CAMK 1e-88 303.1 1 256 256 149 150 151 153 155 40 57 61 129 131 130 132 191 178 173 172 171 170 169 168 167 87 Maternal embryonic leucine zipper kinase
CK1 VRK1 VRK1_HUMAN 6CMMB Q99986 23 341 396.0 F7D:401 Type1 Inactive DFGin 8.476 14.483 BLAminus -115.06, 177.55 64.23, 84.91 -98.08, 23.22 291.58, 82.57 -66.41, -28.16 in-in in 7.601 Saltbr-in 2.897 HRD-in -88.21, -48.16 77.0, 4.0 in-in-out SNCiio in-out ActLoopNT-in 2.959 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -59.62, 146.4 APE9-dihe-na 107.7, -170.45 APE8-dihe-in -90.13, 117.89 APE8-rot-in 302.22 APE67-dihe-in -67.83, -25.02 -51.39, -42.58 APE12-dist-out 15.037 APE11-dist-in 13.451 APE10-dist-in 7.738 APE9-dist-in 4.065 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.1 0.192 0.222 B 364 310 9 0 0 0 [[37, 326]] 1.0 6cmm Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1 261 261 196 197 198 200 202 71 83 87 174 176 175 177 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CMMD Q99986 23 341 396.0 F7D:401 Type1 Inactive DFGin 8.303 14.576 BLAminus -120.35, -178.73 57.57, 80.72 -90.78, 22.63 288.79, 76.0 -64.84, -22.8 in-in in 7.794 Saltbr-in 2.995 HRD-in -88.03, -46.07 76.94, -0.28 in-in-out SNCiio in-out ActLoopNT-in 2.909 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -59.16, 154.16 APE9-dihe-na 94.99, -165.63 APE8-dihe-in -97.55, 123.52 APE8-rot-in 296.28 APE67-dihe-in -67.77, -24.35 -58.36, -42.41 APE12-dist-out 14.924 APE11-dist-in 13.193 APE10-dist-in 7.433 APE9-dist-in 4.166 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.1 0.192 0.222 D 364 315 4 0 0 0 [[37, 326]] 1.0 6cmm Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1 261 261 196 197 198 200 202 71 83 87 174 176 175 177 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1

Ligand: F7D

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name