Ligand: F7D

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 6CMMD
None None 1 33.3% 6VXRA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CAMK MELK MELK_HUMAN 6VXRA 2.1 Inactive None‑None out-none none-out nonTYR APEdihe_aaoii APEdist_nnno F7D Type1 1 - 332 0 None None Maternal embryonic leucine zipper kinase
CK1 VRK1 VRK1_HUMAN 6CMMB 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F7D Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6CMMD 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F7D Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1

Ligand: F7D

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 6CMMD
None None 1 33.3% 6VXRA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK MELK MELK_HUMAN 6VXRA 2.1 Inactive None‑None out-none none-out nonTYR APEdihe_aaoii APEdist_nnno F7D Type1 1 - 332 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
CK1 VRK1 VRK1_HUMAN 6CMMB 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F7D Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens
CK1 VRK1 VRK1_HUMAN 6CMMD 2.1 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii F7D Type1 23 - 341 0 None K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A Serine/threonine-protein kinase VRK1 Homo sapiens

Ligand: F7D

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism