Ligand: EAQ

Total number of chains: 2
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6FYRA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK1 CLK1_HUMAN 6FYOA P49759 148 481 484.0 EAQ:501 Type1 Active DFGin 7.1303 14.6092 BLAminus -126.41, -177.97 57.7, 79.82 -101.45, 23.66 290.45, 86.2 -71.99, -23.62 in-in in 8.2538 Saltbr-in 2.8261 HRD-in -67.73, -44.39 69.27, -21.51 in-in-in SNCiii in-in ActLoopNT-in 2.7761 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.41, 162.2 APE9-dihe-na 76.62, 158.52 APE8-dihe-in -81.15, 137.38 APE8-rot-in 320.28 APE67-dihe-in -54.52, -12.47 -37.95, -53.62 APE12-dist-in 13.1043 APE11-dist-in 11.2911 APE10-dist-in 7.0165 APE9-dist-in 3.2103 None None None XRAY 2.32 0.204 0.234 A 339.0 331.0 3 25 25 0 [[161, 477]] 1.0 6fyo CMGC_CLK1_HUMAN CMGC 2e-93 318.8 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK3 CLK3_HUMAN 6FYRA P49761 128 482 490.0 EAQ:501 Type1 Active DFGin 7.2967 14.9544 BLAminus -115.95, 177.91 58.36, 76.24 -88.91, 20.29 289.13, 90.27 -67.91, -10.88 in-in in 8.6011 Saltbr-in 2.783 HRD-in -72.14, -50.57 79.38, -13.15 in-in-in SNCiii in-in ActLoopNT-in 2.9384 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -110.54, 170.83 APE9-dihe-na 72.55, 158.51 APE8-dihe-in -81.87, 143.54 APE8-rot-in 293.24 APE67-dihe-in -63.5, -22.86 -31.38, -60.72 APE12-dist-in 12.9746 APE11-dist-in 12.0455 APE10-dist-in 7.4382 APE9-dist-in 2.9728 None None None XRAY 1.42 0.177 0.189 A 360.0 355.0 2 25 25 0 [[156, 472]] 1.0 6fyr CMGC_CLK3_HUMAN CMGC 1.2e-90 309.6 1.0 301.0 301.0 319 320 321 323 325 186 201 205 280 282 281 283.0 356 344 339 338 337 336 335 334 333 237 Dual specificity protein kinase CLK3

Ligand: EAQ

Total number of chains: 2
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6FYRA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK1 CLK1_HUMAN 6FYOA P49759 148 481 484.0 EAQ:501 Type1 Active DFGin 7.1303 14.6092 BLAminus -126.41, -177.97 57.7, 79.82 -101.45, 23.66 290.45, 86.2 -71.99, -23.62 in-in in 8.2538 Saltbr-in 2.8261 HRD-in -67.73, -44.39 69.27, -21.51 in-in-in SNCiii in-in ActLoopNT-in 2.7761 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.41, 162.2 APE9-dihe-na 76.62, 158.52 APE8-dihe-in -81.15, 137.38 APE8-rot-in 320.28 APE67-dihe-in -54.52, -12.47 -37.95, -53.62 APE12-dist-in 13.1043 APE11-dist-in 11.2911 APE10-dist-in 7.0165 APE9-dist-in 3.2103 None None None XRAY 2.32 0.204 0.234 A 339.0 331.0 3 25 25 0 [[161, 477]] 1.0 6fyo Homo sapiens CMGC_CLK1_HUMAN CMGC 2e-93 318.8 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK3 CLK3_HUMAN 6FYRA P49761 128 482 490.0 EAQ:501 Type1 Active DFGin 7.2967 14.9544 BLAminus -115.95, 177.91 58.36, 76.24 -88.91, 20.29 289.13, 90.27 -67.91, -10.88 in-in in 8.6011 Saltbr-in 2.783 HRD-in -72.14, -50.57 79.38, -13.15 in-in-in SNCiii in-in ActLoopNT-in 2.9384 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -110.54, 170.83 APE9-dihe-na 72.55, 158.51 APE8-dihe-in -81.87, 143.54 APE8-rot-in 293.24 APE67-dihe-in -63.5, -22.86 -31.38, -60.72 APE12-dist-in 12.9746 APE11-dist-in 12.0455 APE10-dist-in 7.4382 APE9-dist-in 2.9728 None None None XRAY 1.42 0.177 0.189 A 360.0 355.0 2 25 25 0 [[156, 472]] 1.0 6fyr Homo sapiens CMGC_CLK3_HUMAN CMGC 1.2e-90 309.6 1.0 301.0 301.0 319 320 321 323 325 186 201 205 280 282 281 283.0 356 344 339 338 337 336 335 334 333 237 Dual specificity protein kinase CLK3

Ligand: EAQ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name