Ligand: BZ9

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 3DA6A
DFGin BLAminus 1 50.0% 7I8EA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CSNK2A1 CSK21_HUMAN 7I8EA P68400 3 329 391.0 A1BZ9:401 Type1 Active DFGin 7.6918 16.3181 BLAminus -110.6, -177.97 51.08, 79.53 -92.18, 25.95 297.07, 77.06 -71.55, -24.99 in-in in 9.2111 Saltbr-in 2.7896 HRD-in -71.48, -49.28 68.74, 7.8 in-in-in SNCiii in-in ActLoopNT-in 2.9878 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.85, 168.28 APE9-dihe-na 60.52, 161.82 APE8-dihe-in -87.67, 145.92 APE8-rot-in 287.85 APE67-dihe-in -68.33, -18.65 -30.24, -57.29 APE12-dist-in 12.7204 APE11-dist-in 10.5068 APE10-dist-in 6.2352 APE9-dist-in 3.3143 R21S,K74A,K75A,K76A None None XRAY 1.66 0.209 0.244 A 328.0 327.0 0 27 27 0 [[39, 324]] 1.0 7i8e CMGC_CSNK2A1_HUMAN CMGC 8.1e-69 238.0 1.0 301.0 301.0 174 175 176 178 180 68 81 85 153 155 154 156.0 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC MAPK10 MK10_HUMAN 3DA6A P53779 46 401 464.0 BZ9:1 Type1.5_Front Inactive DFGin 3.9287 14.7466 ABAminus -106.52, -2.79 -134.69, 178.18 -120.78, 7.15 305.58, 102.19 77.8, -154.0 out-out out 11.1647 Saltbr-out 7.5632 HRD-in -66.32, -64.11 78.04, -4.14 out-out-out SNCooo out-out ActLoopNT-out 7.5454 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 119.26 APE9-dihe-na -81.12, 139.86 APE8-dihe-in -90.77, 119.11 APE8-rot-out 151.47 APE67-dihe-in -57.67, -20.17 -106.88, -4.35 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 17.0194 APE9-dist-out 11.8293 None None None XRAY 2.0 0.259 0.32 A 364.0 328.0 12 27 17 10 [[64, 359]] 1.0 3da6 CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.1 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10

Ligand: BZ9

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 3DA6A
DFGin BLAminus 1 50.0% 7I8EA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CSNK2A1 CSK21_HUMAN 7I8EA P68400 3 329 391.0 A1BZ9:401 Type1 Active DFGin 7.6918 16.3181 BLAminus -110.6, -177.97 51.08, 79.53 -92.18, 25.95 297.07, 77.06 -71.55, -24.99 in-in in 9.2111 Saltbr-in 2.7896 HRD-in -71.48, -49.28 68.74, 7.8 in-in-in SNCiii in-in ActLoopNT-in 2.9878 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.85, 168.28 APE9-dihe-na 60.52, 161.82 APE8-dihe-in -87.67, 145.92 APE8-rot-in 287.85 APE67-dihe-in -68.33, -18.65 -30.24, -57.29 APE12-dist-in 12.7204 APE11-dist-in 10.5068 APE10-dist-in 6.2352 APE9-dist-in 3.3143 R21S,K74A,K75A,K76A None None XRAY 1.66 0.209 0.244 A 328.0 327.0 0 27 27 0 [[39, 324]] 1.0 7i8e Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 8.1e-69 238.0 1.0 301.0 301.0 174 175 176 178 180 68 81 85 153 155 154 156.0 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC MAPK10 MK10_HUMAN 3DA6A P53779 46 401 464.0 BZ9:1 Type1.5_Front Inactive DFGin 3.9287 14.7466 ABAminus -106.52, -2.79 -134.69, 178.18 -120.78, 7.15 305.58, 102.19 77.8, -154.0 out-out out 11.1647 Saltbr-out 7.5632 HRD-in -66.32, -64.11 78.04, -4.14 out-out-out SNCooo out-out ActLoopNT-out 7.5454 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnoo APE10-dihe-na 999.0, 119.26 APE9-dihe-na -81.12, 139.86 APE8-dihe-in -90.77, 119.11 APE8-rot-out 151.47 APE67-dihe-in -57.67, -20.17 -106.88, -4.35 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 17.0194 APE9-dist-out 11.8293 None None None XRAY 2.0 0.259 0.32 A 364.0 328.0 12 27 17 10 [[64, 359]] 1.0 3da6 Homo sapiens CMGC_MAPK10_HUMAN CMGC 1.4e-85 293.1 1.0 301.0 301.0 206 207 208 210 212 93 111 115 186 188 187 189.0 245 233 228 227 226 225 224 223 222 147 Mitogen-activated protein kinase 10

Ligand: BZ9

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name