Ligand: APJ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name

Ligand: APJ

Total number of chains: 28
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 28 100.0% 3FBVA
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER IRE1 IRE1_YEAST 3FBVA P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.705 14.018 BLAminus -155.94, -171.83 51.84, 75.56 -90.71, 16.67 284.93, 54.03 -51.12, -47.5 in-in in 8.226 Saltbr-in 2.882 HRD-out -65.37, 168.2 -142.48, -40.22 in-in-out SNCiio in-out ActLoopNT-in 2.92 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -68.64, -71.57 APE9-dihe-na -48.48, -43.22 APE8-dihe-out -62.92, -22.72 APE8-rot-in 321.13 APE67-dihe-in -67.45, -5.69 -81.19, 4.2 APE12-dist-in 11.864 APE11-dist-in 13.355 APE10-dist-out 16.922 APE9-dist-out 12.414 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 A 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVB P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.693 14.005 BLAminus -155.81, -172.72 52.4, 76.14 -90.25, 17.16 285.13, 54.57 -51.5, -48.41 in-in in 8.209 Saltbr-in 2.89 HRD-out -65.21, 168.65 -143.41, -39.41 in-in-out SNCiio in-out ActLoopNT-in 2.909 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -69.49, -70.89 APE9-dihe-na -48.37, -43.74 APE8-dihe-out -62.39, -22.65 APE8-rot-in 321.26 APE67-dihe-in -67.5, -6.25 -81.2, 4.55 APE12-dist-in 11.859 APE11-dist-in 13.35 APE10-dist-out 16.897 APE9-dist-out 12.441 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 B 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVC P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.701 14.023 BLAminus -155.56, -172.1 52.0, 74.67 -89.02, 16.83 285.94, 55.3 -51.44, -48.21 in-in in 8.213 Saltbr-in 2.86 HRD-out -65.9, 169.36 -142.91, -40.42 in-in-out SNCiio in-out ActLoopNT-in 2.892 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -67.96, -71.8 APE9-dihe-na -48.56, -43.53 APE8-dihe-out -62.69, -22.67 APE8-rot-in 320.74 APE67-dihe-in -66.41, -6.37 -80.68, 3.45 APE12-dist-in 11.861 APE11-dist-in 13.35 APE10-dist-out 16.924 APE9-dist-out 12.469 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 C 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVD P32361 663 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.681 13.993 BLAminus -155.13, -173.01 52.6, 74.31 -88.7, 16.58 285.55, 54.27 -51.01, -47.76 in-in in 8.207 Saltbr-in 2.873 HRD-out -65.8, 168.8 -142.68, -39.31 in-in-out SNCiio in-out ActLoopNT-in 2.898 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -68.87, -71.59 APE9-dihe-na -48.13, -43.88 APE8-dihe-out -62.92, -22.21 APE8-rot-in 320.9 APE67-dihe-in -66.86, -6.08 -81.23, 4.34 APE12-dist-in 11.864 APE11-dist-in 13.357 APE10-dist-out 16.918 APE9-dist-out 12.446 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 D 448 425 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVE P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.669 13.996 BLAminus -155.73, -172.56 52.63, 75.51 -90.42, 16.46 285.18, 54.55 -50.68, -48.18 in-in in 8.206 Saltbr-in 2.855 HRD-out -66.24, 168.16 -142.69, -39.82 in-in-out SNCiio in-out ActLoopNT-in 2.897 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -68.62, -71.54 APE9-dihe-na -47.96, -44.17 APE8-dihe-out -62.9, -22.53 APE8-rot-in 320.95 APE67-dihe-in -67.45, -6.85 -80.89, 4.84 APE12-dist-in 11.872 APE11-dist-in 13.361 APE10-dist-out 16.921 APE9-dist-out 12.423 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 E 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVF P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.709 14.029 BLAminus -156.5, -172.41 52.56, 74.53 -89.72, 17.29 285.3, 54.51 -52.05, -47.38 in-in in 8.207 Saltbr-in 2.827 HRD-out -65.22, 168.44 -142.39, -39.81 in-in-out SNCiio in-out ActLoopNT-in 2.902 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -69.01, -71.75 APE9-dihe-na -47.94, -44.27 APE8-dihe-out -62.39, -22.42 APE8-rot-in 321.14 APE67-dihe-in -68.2, -4.95 -81.14, 4.25 APE12-dist-in 11.869 APE11-dist-in 13.365 APE10-dist-out 16.922 APE9-dist-out 12.443 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 F 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVG P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.68 14.002 BLAminus -155.85, -172.76 52.32, 75.2 -90.36, 16.74 285.35, 53.85 -50.76, -48.27 in-in in 8.209 Saltbr-in 2.861 HRD-out -65.41, 167.47 -142.49, -40.17 in-in-out SNCiio in-out ActLoopNT-in 2.9 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -68.98, -71.4 APE9-dihe-na -48.52, -43.35 APE8-dihe-out -62.87, -22.64 APE8-rot-in 320.97 APE67-dihe-in -68.88, -5.32 -81.1, 5.04 APE12-dist-in 11.863 APE11-dist-in 13.355 APE10-dist-out 16.915 APE9-dist-out 12.424 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 G 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVH P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.689 14.017 BLAminus -155.63, -172.16 52.36, 75.16 -90.66, 17.09 285.24, 53.64 -51.1, -47.55 in-in in 8.203 Saltbr-in 2.845 HRD-out -65.19, 167.39 -142.19, -40.16 in-in-out SNCiio in-out ActLoopNT-in 2.926 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -68.93, -71.32 APE9-dihe-na -48.49, -43.44 APE8-dihe-out -63.24, -22.34 APE8-rot-in 320.8 APE67-dihe-in -68.45, -5.21 -81.25, 5.03 APE12-dist-in 11.861 APE11-dist-in 13.354 APE10-dist-out 16.912 APE9-dist-out 12.416 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 H 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVI P32361 672 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.714 14.017 BLAminus -156.02, -172.35 52.06, 75.31 -90.02, 16.62 285.55, 53.98 -51.0, -47.91 in-in in 8.21 Saltbr-in 2.849 HRD-out -65.09, 167.81 -142.72, -40.77 in-in-out SNCiio in-out ActLoopNT-in 2.903 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -69.32, -71.61 APE9-dihe-na -48.37, -43.48 APE8-dihe-out -62.95, -22.66 APE8-rot-in 321.08 APE67-dihe-in -68.73, -5.3 -80.88, 4.84 APE12-dist-in 11.843 APE11-dist-in 13.35 APE10-dist-out 16.913 APE9-dist-out 12.434 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 I 448 416 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVJ P32361 672 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.69 14.012 BLAminus -155.85, -172.44 52.57, 75.34 -90.52, 16.37 285.27, 53.91 -50.64, -47.8 in-in in 8.201 Saltbr-in 2.852 HRD-out -65.21, 168.05 -142.86, -40.55 in-in-out SNCiio in-out ActLoopNT-in 2.913 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -69.02, -71.29 APE9-dihe-na -48.68, -43.34 APE8-dihe-out -63.13, -22.6 APE8-rot-in 320.84 APE67-dihe-in -68.73, -5.07 -80.86, 4.78 APE12-dist-in 11.858 APE11-dist-in 13.353 APE10-dist-out 16.917 APE9-dist-out 12.427 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 J 448 416 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVK P32361 663 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.691 14.007 BLAminus -156.26, -172.13 51.99, 75.85 -90.75, 16.87 285.07, 54.48 -51.1, -47.86 in-in in 8.213 Saltbr-in 2.827 HRD-out -65.48, 167.26 -142.09, -40.2 in-in-out SNCiio in-out ActLoopNT-in 2.908 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -69.03, -71.43 APE9-dihe-na -48.67, -43.3 APE8-dihe-out -62.84, -22.69 APE8-rot-in 320.9 APE67-dihe-in -68.45, -5.64 -81.1, 4.88 APE12-dist-in 11.857 APE11-dist-in 13.353 APE10-dist-out 16.911 APE9-dist-out 12.434 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 K 448 425 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVL P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.703 14.012 BLAminus -155.79, -172.44 52.01, 75.2 -90.74, 17.2 285.43, 54.09 -51.45, -47.79 in-in in 8.211 Saltbr-in 2.849 HRD-out -65.26, 167.87 -142.94, -40.28 in-in-out SNCiio in-out ActLoopNT-in 2.901 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -68.81, -71.59 APE9-dihe-na -48.24, -43.79 APE8-dihe-out -62.8, -22.54 APE8-rot-in 320.86 APE67-dihe-in -68.12, -5.45 -81.06, 4.67 APE12-dist-in 11.862 APE11-dist-in 13.358 APE10-dist-out 16.926 APE9-dist-out 12.427 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 L 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVM P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.697 14.012 BLAminus -156.04, -172.14 51.82, 75.37 -89.83, 16.81 285.35, 54.26 -51.35, -47.4 in-in in 8.21 Saltbr-in 2.844 HRD-out -66.69, 167.72 -142.42, -40.06 in-in-out SNCiio in-out ActLoopNT-in 2.913 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -68.59, -71.54 APE9-dihe-na -48.4, -43.24 APE8-dihe-out -63.11, -22.55 APE8-rot-in 321.07 APE67-dihe-in -67.8, -5.48 -81.21, 4.6 APE12-dist-in 11.866 APE11-dist-in 13.355 APE10-dist-out 16.919 APE9-dist-out 12.426 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 M 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVN P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.694 14.027 BLAminus -156.62, -171.86 51.92, 75.49 -90.2, 17.25 284.59, 54.76 -51.95, -47.33 in-in in 8.204 Saltbr-in 2.813 HRD-out -65.53, 169.2 -143.21, -40.58 in-in-out SNCiio in-out ActLoopNT-in 2.913 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -68.63, -71.51 APE9-dihe-na -48.37, -43.89 APE8-dihe-out -62.53, -22.39 APE8-rot-in 321.21 APE67-dihe-in -66.15, -6.02 -81.75, 3.84 APE12-dist-in 11.859 APE11-dist-in 13.359 APE10-dist-out 16.916 APE9-dist-out 12.438 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 N 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJA P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.576 14.69 BLAminus -148.71, -168.46 54.17, 67.67 -78.94, 6.4 276.48, 44.99 -41.8, -54.71 in-in in 8.639 Saltbr-in 2.811 HRD-out -63.68, 156.21 -136.62, -35.13 in-in-out SNCiio in-out ActLoopNT-in 3.137 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.15, -68.53 APE9-dihe-na -53.15, -43.1 APE8-dihe-out -56.81, -22.13 APE8-rot-in 313.68 APE67-dihe-in -64.06, -14.16 -80.53, 2.66 APE12-dist-in 11.777 APE11-dist-in 13.05 APE10-dist-out 16.866 APE9-dist-out 12.349 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 A 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJB P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.622 14.699 BLAminus -145.97, -168.7 54.87, 65.94 -77.36, 6.26 277.2, 45.55 -41.04, -56.95 in-in in 8.617 Saltbr-in 2.756 HRD-out -64.81, 156.69 -137.72, -34.35 in-in-out SNCiio in-out ActLoopNT-in 3.151 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.31, -68.26 APE9-dihe-na -53.94, -42.41 APE8-dihe-out -57.37, -21.3 APE8-rot-in 314.03 APE67-dihe-in -64.97, -13.26 -80.89, 2.66 APE12-dist-in 11.758 APE11-dist-in 13.039 APE10-dist-out 16.852 APE9-dist-out 12.323 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 B 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJC P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.601 14.667 BLAminus -148.09, -168.39 54.61, 67.07 -78.67, 4.63 277.17, 45.68 -39.89, -56.61 in-in in 8.658 Saltbr-in 2.767 HRD-out -66.32, 158.42 -137.55, -34.7 in-in-out SNCiio in-out ActLoopNT-in 3.177 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.05, -68.32 APE9-dihe-na -53.45, -42.63 APE8-dihe-out -57.75, -21.11 APE8-rot-in 313.65 APE67-dihe-in -64.89, -12.55 -80.49, 1.84 APE12-dist-in 11.764 APE11-dist-in 13.037 APE10-dist-out 16.866 APE9-dist-out 12.346 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 C 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJD P32361 663 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.566 14.675 BLAminus -147.8, -169.08 55.27, 66.77 -78.15, 5.02 276.86, 45.51 -40.71, -55.79 in-in in 8.645 Saltbr-in 2.801 HRD-out -65.92, 158.2 -137.14, -33.69 in-in-out SNCiio in-out ActLoopNT-in 3.138 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.38, -68.21 APE9-dihe-na -53.57, -42.55 APE8-dihe-out -57.56, -21.08 APE8-rot-in 313.32 APE67-dihe-in -63.33, -13.71 -81.51, 2.27 APE12-dist-in 11.773 APE11-dist-in 13.049 APE10-dist-out 16.864 APE9-dist-out 12.38 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 D 448 425 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJE P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.585 14.643 BLAminus -147.96, -168.81 54.2, 67.49 -78.57, 5.35 277.08, 45.62 -38.76, -57.11 in-in in 8.637 Saltbr-in 2.769 HRD-out -65.11, 156.88 -136.96, -33.74 in-in-out SNCiio in-out ActLoopNT-in 3.112 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.58, -68.38 APE9-dihe-na -53.33, -42.75 APE8-dihe-out -57.13, -21.54 APE8-rot-in 313.33 APE67-dihe-in -64.35, -12.66 -81.14, 2.48 APE12-dist-in 11.772 APE11-dist-in 13.052 APE10-dist-out 16.864 APE9-dist-out 12.349 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 E 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJF P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.634 14.679 BLAminus -147.21, -170.07 56.23, 67.33 -78.59, 5.02 276.52, 45.62 -39.56, -57.56 in-in in 8.637 Saltbr-in 2.753 HRD-out -65.32, 157.31 -138.05, -34.96 in-in-out SNCiio in-out ActLoopNT-in 3.136 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.05, -68.71 APE9-dihe-na -53.15, -42.8 APE8-dihe-out -57.57, -21.28 APE8-rot-in 313.4 APE67-dihe-in -65.82, -12.51 -81.14, 2.67 APE12-dist-in 11.776 APE11-dist-in 13.05 APE10-dist-out 16.86 APE9-dist-out 12.349 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 F 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJG P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.566 14.685 BLAminus -147.91, -169.38 55.04, 66.11 -77.54, 5.23 276.22, 46.02 -40.07, -57.31 in-in in 8.643 Saltbr-in 2.748 HRD-out -64.93, 156.04 -136.08, -33.91 in-in-out SNCiio in-out ActLoopNT-in 3.131 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.24, -68.26 APE9-dihe-na -53.63, -42.38 APE8-dihe-out -57.53, -21.78 APE8-rot-in 313.73 APE67-dihe-in -65.84, -12.85 -80.33, 3.17 APE12-dist-in 11.758 APE11-dist-in 13.036 APE10-dist-out 16.85 APE9-dist-out 12.35 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 G 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJH P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.621 14.688 BLAminus -146.79, -168.82 55.25, 66.69 -78.24, 4.98 276.06, 46.02 -40.46, -56.35 in-in in 8.621 Saltbr-in 2.784 HRD-out -63.56, 155.88 -136.32, -32.88 in-in-out SNCiio in-out ActLoopNT-in 3.16 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -79.81, -68.21 APE9-dihe-na -53.12, -42.67 APE8-dihe-out -57.93, -21.27 APE8-rot-in 313.46 APE67-dihe-in -65.36, -13.19 -81.28, 3.09 APE12-dist-in 11.764 APE11-dist-in 13.044 APE10-dist-out 16.864 APE9-dist-out 12.336 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 H 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJI P32361 672 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.597 14.673 BLAminus -144.58, -169.7 55.03, 66.77 -78.68, 7.63 277.09, 44.45 -41.23, -57.07 in-in in 8.644 Saltbr-in 2.744 HRD-out -64.95, 157.55 -138.96, -35.0 in-in-out SNCiio in-out ActLoopNT-in 3.157 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.26, -68.42 APE9-dihe-na -53.86, -41.72 APE8-dihe-out -58.23, -21.49 APE8-rot-in 313.77 APE67-dihe-in -65.66, -13.81 -80.4, 2.87 APE12-dist-in 11.744 APE11-dist-in 13.045 APE10-dist-out 16.858 APE9-dist-out 12.35 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 I 448 416 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJJ P32361 672 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.59 14.633 BLAminus -147.79, -169.52 54.31, 67.44 -79.0, 5.2 277.14, 44.53 -38.95, -56.95 in-in in 8.65 Saltbr-in 2.85 HRD-out -64.62, 158.43 -139.24, -34.9 in-in-out SNCiio in-out ActLoopNT-in 3.128 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -79.96, -68.28 APE9-dihe-na -53.84, -42.07 APE8-dihe-out -57.85, -21.67 APE8-rot-in 313.62 APE67-dihe-in -64.62, -13.74 -80.34, 2.74 APE12-dist-in 11.775 APE11-dist-in 13.048 APE10-dist-out 16.875 APE9-dist-out 12.359 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 J 448 416 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJK P32361 663 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.574 14.666 BLAminus -147.34, -168.85 53.94, 68.17 -79.5, 5.5 275.62, 45.59 -40.3, -55.51 in-in in 8.638 Saltbr-in 2.759 HRD-out -62.49, 157.82 -138.19, -35.16 in-in-out SNCiio in-out ActLoopNT-in 3.19 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.53, -68.04 APE9-dihe-na -53.7, -42.51 APE8-dihe-out -57.97, -20.89 APE8-rot-in 313.46 APE67-dihe-in -65.09, -12.68 -80.87, 2.48 APE12-dist-in 11.759 APE11-dist-in 13.045 APE10-dist-out 16.854 APE9-dist-out 12.369 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 K 448 425 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJL P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.603 14.692 BLAminus -146.91, -170.98 55.17, 67.62 -78.94, 5.58 276.27, 47.05 -40.69, -57.56 in-in in 8.613 Saltbr-in 2.774 HRD-out -64.87, 156.97 -138.1, -35.43 in-in-out SNCiio in-out ActLoopNT-in 3.111 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.31, -68.63 APE9-dihe-na -52.88, -42.97 APE8-dihe-out -57.52, -21.23 APE8-rot-in 313.42 APE67-dihe-in -65.26, -12.89 -80.93, 2.33 APE12-dist-in 11.765 APE11-dist-in 13.039 APE10-dist-out 16.857 APE9-dist-out 12.373 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 L 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJM P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.646 14.668 BLAminus -146.9, -168.44 53.9, 67.89 -79.35, 4.39 276.45, 46.55 -39.29, -56.45 in-in in 8.635 Saltbr-in 2.747 HRD-out -66.22, 157.3 -138.26, -33.17 in-in-out SNCiio in-out ActLoopNT-in 3.13 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -79.74, -68.15 APE9-dihe-na -53.74, -42.77 APE8-dihe-out -57.66, -21.0 APE8-rot-in 313.3 APE67-dihe-in -64.76, -12.86 -81.09, 2.72 APE12-dist-in 11.767 APE11-dist-in 13.036 APE10-dist-out 16.864 APE9-dist-out 12.334 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 M 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJN P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.605 14.701 BLAminus -148.53, -170.95 56.63, 67.6 -79.17, 5.37 275.48, 45.81 -40.74, -55.45 in-in in 8.63 Saltbr-in 2.84 HRD-out -66.17, 156.27 -136.96, -35.68 in-in-out SNCiio in-out ActLoopNT-in 3.14 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.8, -68.16 APE9-dihe-na -53.36, -42.69 APE8-dihe-out -57.82, -20.86 APE8-rot-in 313.36 APE67-dihe-in -64.72, -13.44 -81.59, 3.36 APE12-dist-in 11.772 APE11-dist-in 13.041 APE10-dist-out 16.85 APE9-dist-out 12.354 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 N 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1

Ligand: APJ

Total number of chains: 28
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 28 100.0% 3FBVA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
OTHER IRE1 IRE1_YEAST 3FBVA P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.705 14.018 BLAminus -155.94, -171.83 51.84, 75.56 -90.71, 16.67 284.93, 54.03 -51.12, -47.5 in-in in 8.226 Saltbr-in 2.882 HRD-out -65.37, 168.2 -142.48, -40.22 in-in-out SNCiio in-out ActLoopNT-in 2.92 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -68.64, -71.57 APE9-dihe-na -48.48, -43.22 APE8-dihe-out -62.92, -22.72 APE8-rot-in 321.13 APE67-dihe-in -67.45, -5.69 -81.19, 4.2 APE12-dist-in 11.864 APE11-dist-in 13.355 APE10-dist-out 16.922 APE9-dist-out 12.414 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 A 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVB P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.693 14.005 BLAminus -155.81, -172.72 52.4, 76.14 -90.25, 17.16 285.13, 54.57 -51.5, -48.41 in-in in 8.209 Saltbr-in 2.89 HRD-out -65.21, 168.65 -143.41, -39.41 in-in-out SNCiio in-out ActLoopNT-in 2.909 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -69.49, -70.89 APE9-dihe-na -48.37, -43.74 APE8-dihe-out -62.39, -22.65 APE8-rot-in 321.26 APE67-dihe-in -67.5, -6.25 -81.2, 4.55 APE12-dist-in 11.859 APE11-dist-in 13.35 APE10-dist-out 16.897 APE9-dist-out 12.441 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 B 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVC P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.701 14.023 BLAminus -155.56, -172.1 52.0, 74.67 -89.02, 16.83 285.94, 55.3 -51.44, -48.21 in-in in 8.213 Saltbr-in 2.86 HRD-out -65.9, 169.36 -142.91, -40.42 in-in-out SNCiio in-out ActLoopNT-in 2.892 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -67.96, -71.8 APE9-dihe-na -48.56, -43.53 APE8-dihe-out -62.69, -22.67 APE8-rot-in 320.74 APE67-dihe-in -66.41, -6.37 -80.68, 3.45 APE12-dist-in 11.861 APE11-dist-in 13.35 APE10-dist-out 16.924 APE9-dist-out 12.469 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 C 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVD P32361 663 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.681 13.993 BLAminus -155.13, -173.01 52.6, 74.31 -88.7, 16.58 285.55, 54.27 -51.01, -47.76 in-in in 8.207 Saltbr-in 2.873 HRD-out -65.8, 168.8 -142.68, -39.31 in-in-out SNCiio in-out ActLoopNT-in 2.898 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -68.87, -71.59 APE9-dihe-na -48.13, -43.88 APE8-dihe-out -62.92, -22.21 APE8-rot-in 320.9 APE67-dihe-in -66.86, -6.08 -81.23, 4.34 APE12-dist-in 11.864 APE11-dist-in 13.357 APE10-dist-out 16.918 APE9-dist-out 12.446 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 D 448 425 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVE P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.669 13.996 BLAminus -155.73, -172.56 52.63, 75.51 -90.42, 16.46 285.18, 54.55 -50.68, -48.18 in-in in 8.206 Saltbr-in 2.855 HRD-out -66.24, 168.16 -142.69, -39.82 in-in-out SNCiio in-out ActLoopNT-in 2.897 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -68.62, -71.54 APE9-dihe-na -47.96, -44.17 APE8-dihe-out -62.9, -22.53 APE8-rot-in 320.95 APE67-dihe-in -67.45, -6.85 -80.89, 4.84 APE12-dist-in 11.872 APE11-dist-in 13.361 APE10-dist-out 16.921 APE9-dist-out 12.423 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 E 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVF P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.709 14.029 BLAminus -156.5, -172.41 52.56, 74.53 -89.72, 17.29 285.3, 54.51 -52.05, -47.38 in-in in 8.207 Saltbr-in 2.827 HRD-out -65.22, 168.44 -142.39, -39.81 in-in-out SNCiio in-out ActLoopNT-in 2.902 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -69.01, -71.75 APE9-dihe-na -47.94, -44.27 APE8-dihe-out -62.39, -22.42 APE8-rot-in 321.14 APE67-dihe-in -68.2, -4.95 -81.14, 4.25 APE12-dist-in 11.869 APE11-dist-in 13.365 APE10-dist-out 16.922 APE9-dist-out 12.443 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 F 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVG P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.68 14.002 BLAminus -155.85, -172.76 52.32, 75.2 -90.36, 16.74 285.35, 53.85 -50.76, -48.27 in-in in 8.209 Saltbr-in 2.861 HRD-out -65.41, 167.47 -142.49, -40.17 in-in-out SNCiio in-out ActLoopNT-in 2.9 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -68.98, -71.4 APE9-dihe-na -48.52, -43.35 APE8-dihe-out -62.87, -22.64 APE8-rot-in 320.97 APE67-dihe-in -68.88, -5.32 -81.1, 5.04 APE12-dist-in 11.863 APE11-dist-in 13.355 APE10-dist-out 16.915 APE9-dist-out 12.424 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 G 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVH P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.689 14.017 BLAminus -155.63, -172.16 52.36, 75.16 -90.66, 17.09 285.24, 53.64 -51.1, -47.55 in-in in 8.203 Saltbr-in 2.845 HRD-out -65.19, 167.39 -142.19, -40.16 in-in-out SNCiio in-out ActLoopNT-in 2.926 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -68.93, -71.32 APE9-dihe-na -48.49, -43.44 APE8-dihe-out -63.24, -22.34 APE8-rot-in 320.8 APE67-dihe-in -68.45, -5.21 -81.25, 5.03 APE12-dist-in 11.861 APE11-dist-in 13.354 APE10-dist-out 16.912 APE9-dist-out 12.416 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 H 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVI P32361 672 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.714 14.017 BLAminus -156.02, -172.35 52.06, 75.31 -90.02, 16.62 285.55, 53.98 -51.0, -47.91 in-in in 8.21 Saltbr-in 2.849 HRD-out -65.09, 167.81 -142.72, -40.77 in-in-out SNCiio in-out ActLoopNT-in 2.903 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -69.32, -71.61 APE9-dihe-na -48.37, -43.48 APE8-dihe-out -62.95, -22.66 APE8-rot-in 321.08 APE67-dihe-in -68.73, -5.3 -80.88, 4.84 APE12-dist-in 11.843 APE11-dist-in 13.35 APE10-dist-out 16.913 APE9-dist-out 12.434 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 I 448 416 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVJ P32361 672 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.69 14.012 BLAminus -155.85, -172.44 52.57, 75.34 -90.52, 16.37 285.27, 53.91 -50.64, -47.8 in-in in 8.201 Saltbr-in 2.852 HRD-out -65.21, 168.05 -142.86, -40.55 in-in-out SNCiio in-out ActLoopNT-in 2.913 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -69.02, -71.29 APE9-dihe-na -48.68, -43.34 APE8-dihe-out -63.13, -22.6 APE8-rot-in 320.84 APE67-dihe-in -68.73, -5.07 -80.86, 4.78 APE12-dist-in 11.858 APE11-dist-in 13.353 APE10-dist-out 16.917 APE9-dist-out 12.427 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 J 448 416 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVK P32361 663 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.691 14.007 BLAminus -156.26, -172.13 51.99, 75.85 -90.75, 16.87 285.07, 54.48 -51.1, -47.86 in-in in 8.213 Saltbr-in 2.827 HRD-out -65.48, 167.26 -142.09, -40.2 in-in-out SNCiio in-out ActLoopNT-in 2.908 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -69.03, -71.43 APE9-dihe-na -48.67, -43.3 APE8-dihe-out -62.84, -22.69 APE8-rot-in 320.9 APE67-dihe-in -68.45, -5.64 -81.1, 4.88 APE12-dist-in 11.857 APE11-dist-in 13.353 APE10-dist-out 16.911 APE9-dist-out 12.434 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 K 448 425 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVL P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.703 14.012 BLAminus -155.79, -172.44 52.01, 75.2 -90.74, 17.2 285.43, 54.09 -51.45, -47.79 in-in in 8.211 Saltbr-in 2.849 HRD-out -65.26, 167.87 -142.94, -40.28 in-in-out SNCiio in-out ActLoopNT-in 2.901 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -68.81, -71.59 APE9-dihe-na -48.24, -43.79 APE8-dihe-out -62.8, -22.54 APE8-rot-in 320.86 APE67-dihe-in -68.12, -5.45 -81.06, 4.67 APE12-dist-in 11.862 APE11-dist-in 13.358 APE10-dist-out 16.926 APE9-dist-out 12.427 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 L 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVM P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.697 14.012 BLAminus -156.04, -172.14 51.82, 75.37 -89.83, 16.81 285.35, 54.26 -51.35, -47.4 in-in in 8.21 Saltbr-in 2.844 HRD-out -66.69, 167.72 -142.42, -40.06 in-in-out SNCiio in-out ActLoopNT-in 2.913 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -68.59, -71.54 APE9-dihe-na -48.4, -43.24 APE8-dihe-out -63.11, -22.55 APE8-rot-in 321.07 APE67-dihe-in -67.8, -5.48 -81.21, 4.6 APE12-dist-in 11.866 APE11-dist-in 13.355 APE10-dist-out 16.919 APE9-dist-out 12.426 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 M 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3FBVN P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.694 14.027 BLAminus -156.62, -171.86 51.92, 75.49 -90.2, 17.25 284.59, 54.76 -51.95, -47.33 in-in in 8.204 Saltbr-in 2.813 HRD-out -65.53, 169.2 -143.21, -40.58 in-in-out SNCiio in-out ActLoopNT-in 2.913 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -68.63, -71.51 APE9-dihe-na -48.37, -43.89 APE8-dihe-out -62.53, -22.39 APE8-rot-in 321.21 APE67-dihe-in -66.15, -6.02 -81.75, 3.84 APE12-dist-in 11.859 APE11-dist-in 13.359 APE10-dist-out 16.916 APE9-dist-out 12.438 None SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.2 0.237 0.283 N 448 418 0 0 0 0 [[672, 977]] 1.0 3fbv Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJA P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.576 14.69 BLAminus -148.71, -168.46 54.17, 67.67 -78.94, 6.4 276.48, 44.99 -41.8, -54.71 in-in in 8.639 Saltbr-in 2.811 HRD-out -63.68, 156.21 -136.62, -35.13 in-in-out SNCiio in-out ActLoopNT-in 3.137 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.15, -68.53 APE9-dihe-na -53.15, -43.1 APE8-dihe-out -56.81, -22.13 APE8-rot-in 313.68 APE67-dihe-in -64.06, -14.16 -80.53, 2.66 APE12-dist-in 11.777 APE11-dist-in 13.05 APE10-dist-out 16.866 APE9-dist-out 12.349 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 A 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJB P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.622 14.699 BLAminus -145.97, -168.7 54.87, 65.94 -77.36, 6.26 277.2, 45.55 -41.04, -56.95 in-in in 8.617 Saltbr-in 2.756 HRD-out -64.81, 156.69 -137.72, -34.35 in-in-out SNCiio in-out ActLoopNT-in 3.151 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.31, -68.26 APE9-dihe-na -53.94, -42.41 APE8-dihe-out -57.37, -21.3 APE8-rot-in 314.03 APE67-dihe-in -64.97, -13.26 -80.89, 2.66 APE12-dist-in 11.758 APE11-dist-in 13.039 APE10-dist-out 16.852 APE9-dist-out 12.323 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 B 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJC P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.601 14.667 BLAminus -148.09, -168.39 54.61, 67.07 -78.67, 4.63 277.17, 45.68 -39.89, -56.61 in-in in 8.658 Saltbr-in 2.767 HRD-out -66.32, 158.42 -137.55, -34.7 in-in-out SNCiio in-out ActLoopNT-in 3.177 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.05, -68.32 APE9-dihe-na -53.45, -42.63 APE8-dihe-out -57.75, -21.11 APE8-rot-in 313.65 APE67-dihe-in -64.89, -12.55 -80.49, 1.84 APE12-dist-in 11.764 APE11-dist-in 13.037 APE10-dist-out 16.866 APE9-dist-out 12.346 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 C 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJD P32361 663 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.566 14.675 BLAminus -147.8, -169.08 55.27, 66.77 -78.15, 5.02 276.86, 45.51 -40.71, -55.79 in-in in 8.645 Saltbr-in 2.801 HRD-out -65.92, 158.2 -137.14, -33.69 in-in-out SNCiio in-out ActLoopNT-in 3.138 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.38, -68.21 APE9-dihe-na -53.57, -42.55 APE8-dihe-out -57.56, -21.08 APE8-rot-in 313.32 APE67-dihe-in -63.33, -13.71 -81.51, 2.27 APE12-dist-in 11.773 APE11-dist-in 13.049 APE10-dist-out 16.864 APE9-dist-out 12.38 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 D 448 425 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJE P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.585 14.643 BLAminus -147.96, -168.81 54.2, 67.49 -78.57, 5.35 277.08, 45.62 -38.76, -57.11 in-in in 8.637 Saltbr-in 2.769 HRD-out -65.11, 156.88 -136.96, -33.74 in-in-out SNCiio in-out ActLoopNT-in 3.112 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.58, -68.38 APE9-dihe-na -53.33, -42.75 APE8-dihe-out -57.13, -21.54 APE8-rot-in 313.33 APE67-dihe-in -64.35, -12.66 -81.14, 2.48 APE12-dist-in 11.772 APE11-dist-in 13.052 APE10-dist-out 16.864 APE9-dist-out 12.349 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 E 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJF P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.634 14.679 BLAminus -147.21, -170.07 56.23, 67.33 -78.59, 5.02 276.52, 45.62 -39.56, -57.56 in-in in 8.637 Saltbr-in 2.753 HRD-out -65.32, 157.31 -138.05, -34.96 in-in-out SNCiio in-out ActLoopNT-in 3.136 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.05, -68.71 APE9-dihe-na -53.15, -42.8 APE8-dihe-out -57.57, -21.28 APE8-rot-in 313.4 APE67-dihe-in -65.82, -12.51 -81.14, 2.67 APE12-dist-in 11.776 APE11-dist-in 13.05 APE10-dist-out 16.86 APE9-dist-out 12.349 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 F 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJG P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.566 14.685 BLAminus -147.91, -169.38 55.04, 66.11 -77.54, 5.23 276.22, 46.02 -40.07, -57.31 in-in in 8.643 Saltbr-in 2.748 HRD-out -64.93, 156.04 -136.08, -33.91 in-in-out SNCiio in-out ActLoopNT-in 3.131 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.24, -68.26 APE9-dihe-na -53.63, -42.38 APE8-dihe-out -57.53, -21.78 APE8-rot-in 313.73 APE67-dihe-in -65.84, -12.85 -80.33, 3.17 APE12-dist-in 11.758 APE11-dist-in 13.036 APE10-dist-out 16.85 APE9-dist-out 12.35 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 G 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJH P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.621 14.688 BLAminus -146.79, -168.82 55.25, 66.69 -78.24, 4.98 276.06, 46.02 -40.46, -56.35 in-in in 8.621 Saltbr-in 2.784 HRD-out -63.56, 155.88 -136.32, -32.88 in-in-out SNCiio in-out ActLoopNT-in 3.16 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -79.81, -68.21 APE9-dihe-na -53.12, -42.67 APE8-dihe-out -57.93, -21.27 APE8-rot-in 313.46 APE67-dihe-in -65.36, -13.19 -81.28, 3.09 APE12-dist-in 11.764 APE11-dist-in 13.044 APE10-dist-out 16.864 APE9-dist-out 12.336 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 H 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJI P32361 672 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.597 14.673 BLAminus -144.58, -169.7 55.03, 66.77 -78.68, 7.63 277.09, 44.45 -41.23, -57.07 in-in in 8.644 Saltbr-in 2.744 HRD-out -64.95, 157.55 -138.96, -35.0 in-in-out SNCiio in-out ActLoopNT-in 3.157 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.26, -68.42 APE9-dihe-na -53.86, -41.72 APE8-dihe-out -58.23, -21.49 APE8-rot-in 313.77 APE67-dihe-in -65.66, -13.81 -80.4, 2.87 APE12-dist-in 11.744 APE11-dist-in 13.045 APE10-dist-out 16.858 APE9-dist-out 12.35 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 I 448 416 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJJ P32361 672 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.59 14.633 BLAminus -147.79, -169.52 54.31, 67.44 -79.0, 5.2 277.14, 44.53 -38.95, -56.95 in-in in 8.65 Saltbr-in 2.85 HRD-out -64.62, 158.43 -139.24, -34.9 in-in-out SNCiio in-out ActLoopNT-in 3.128 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -79.96, -68.28 APE9-dihe-na -53.84, -42.07 APE8-dihe-out -57.85, -21.67 APE8-rot-in 313.62 APE67-dihe-in -64.62, -13.74 -80.34, 2.74 APE12-dist-in 11.775 APE11-dist-in 13.048 APE10-dist-out 16.875 APE9-dist-out 12.359 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 J 448 416 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJK P32361 663 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.574 14.666 BLAminus -147.34, -168.85 53.94, 68.17 -79.5, 5.5 275.62, 45.59 -40.3, -55.51 in-in in 8.638 Saltbr-in 2.759 HRD-out -62.49, 157.82 -138.19, -35.16 in-in-out SNCiio in-out ActLoopNT-in 3.19 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.53, -68.04 APE9-dihe-na -53.7, -42.51 APE8-dihe-out -57.97, -20.89 APE8-rot-in 313.46 APE67-dihe-in -65.09, -12.68 -80.87, 2.48 APE12-dist-in 11.759 APE11-dist-in 13.045 APE10-dist-out 16.854 APE9-dist-out 12.369 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 K 448 425 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJL P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.603 14.692 BLAminus -146.91, -170.98 55.17, 67.62 -78.94, 5.58 276.27, 47.05 -40.69, -57.56 in-in in 8.613 Saltbr-in 2.774 HRD-out -64.87, 156.97 -138.1, -35.43 in-in-out SNCiio in-out ActLoopNT-in 3.111 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.31, -68.63 APE9-dihe-na -52.88, -42.97 APE8-dihe-out -57.52, -21.23 APE8-rot-in 313.42 APE67-dihe-in -65.26, -12.89 -80.93, 2.33 APE12-dist-in 11.765 APE11-dist-in 13.039 APE10-dist-out 16.857 APE9-dist-out 12.373 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 L 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJM P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.646 14.668 BLAminus -146.9, -168.44 53.9, 67.89 -79.35, 4.39 276.45, 46.55 -39.29, -56.45 in-in in 8.635 Saltbr-in 2.747 HRD-out -66.22, 157.3 -138.26, -33.17 in-in-out SNCiio in-out ActLoopNT-in 3.13 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -79.74, -68.15 APE9-dihe-na -53.74, -42.77 APE8-dihe-out -57.66, -21.0 APE8-rot-in 313.3 APE67-dihe-in -64.76, -12.86 -81.09, 2.72 APE12-dist-in 11.767 APE11-dist-in 13.036 APE10-dist-out 16.864 APE9-dist-out 12.334 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 M 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1
OTHER IRE1 IRE1_YEAST 3SDJN P32361 670 1115 1115.0 APJ:1999 Type1 Inactive DFGin 5.605 14.701 BLAminus -148.53, -170.95 56.63, 67.6 -79.17, 5.37 275.48, 45.81 -40.74, -55.45 in-in in 8.63 Saltbr-in 2.84 HRD-out -66.17, 156.27 -136.96, -35.68 in-in-out SNCiio in-out ActLoopNT-in 3.14 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iioo APE10-dihe-na -80.8, -68.16 APE9-dihe-na -53.36, -42.69 APE8-dihe-out -57.82, -20.86 APE8-rot-in 313.36 APE67-dihe-in -64.72, -13.44 -81.59, 3.36 APE12-dist-in 11.772 APE11-dist-in 13.041 APE10-dist-out 16.85 APE9-dist-out 12.354 H1061N SEP840,SEP841,TPO844 SEP840,SEP841,TPO844 XRAY 3.65 0.251 0.287 N 448 418 0 0 0 0 [[672, 977]] 1.0 3sdj Saccharomyces cerevisiae OTHER_IRE1_YEAST TKL 3.3e-36 131.3 4 263 260 827 828 829 831 833 702 715 719 794 796 795 797 902 859 854 853 852 851 850 849 848 746 Serine/threonine-protein kinase/endoribonuclease IRE1