Ligand: A3F

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 3MTFA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 3MTFA Q04771 203 498 509.0 A3F:1 Type1 Inactive DFGin 7.0905 13.2083 BLAminus -126.1, 157.67 76.9, 82.69 -86.05, 21.36 306.23, 175.03 -61.66, -24.97 in-out in 8.3313 Saltbr-out 4.1956 HRD-in -82.54, -58.57 79.29, -1.49 out-in-out SNCoio in-out ActLoopNT-in 2.9128 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -103.22, 162.67 APE9-dihe-na -69.88, 165.81 APE8-dihe-in -53.93, 121.99 APE8-rot-in 312.82 APE67-dihe-in -59.42, -28.32 -57.34, -37.41 APE12-dist-in 10.6706 APE11-dist-out 6.476 APE10-dist-out 9.4819 APE9-dist-in 4.0726 Q207D None None XRAY 2.15 0.185 0.244 A 301.0 296.0 0 32 32 0 [[207, 497]] 1.0 3mtf TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 3MTFB Q04771 202 499 509.0 A3F:501 Type1 Inactive DFGin 7.5781 13.3226 BLAminus -114.45, 160.06 82.35, 87.49 -104.83, 25.86 291.12, 164.81 -75.29, -13.54 in-out in 8.5 Saltbr-out 4.2324 HRD-in -82.5, -60.12 85.3, -4.39 out-in-out SNCoio in-out ActLoopNT-in 2.869 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -111.75, 153.3 APE9-dihe-na -57.45, 170.81 APE8-dihe-in -65.39, 131.64 APE8-rot-in 306.28 APE67-dihe-in -49.77, -35.33 -68.1, -43.23 APE12-dist-in 10.6109 APE11-dist-out 6.4527 APE10-dist-out 9.3963 APE9-dist-in 4.1192 Q207D None None XRAY 2.15 0.185 0.244 B 301.0 298.0 0 32 32 0 [[207, 497]] 1.0 3mtf TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6EIXA Q04771 192 503 509.0 A3F:601 Type1 Inactive DFGin 7.3048 13.3822 BLAminus -122.31, 163.89 74.01, 85.68 -98.53, 23.31 310.02, 174.96 -66.89, -23.04 in-out in 9.0828 Saltbr-out 5.1598 HRD-in -81.6, -53.66 78.97, -2.54 out-in-out SNCoio in-out ActLoopNT-in 3.0232 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -113.45, 165.41 APE9-dihe-na -59.94, 163.8 APE8-dihe-in -59.76, 126.51 APE8-rot-in 307.55 APE67-dihe-in -58.05, -30.26 -58.58, -41.78 APE12-dist-in 10.589 APE11-dist-out 6.415 APE10-dist-out 9.3108 APE9-dist-in 3.8713 Q207E None None XRAY 2.3 0.191 0.249 A 340.0 312.0 0 32 32 0 [[207, 497]] 1.0 6eix TKL_ACVR1_HUMAN TKL 2.9e-85 292.0 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: A3F

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 3MTFA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 3MTFA Q04771 203 498 509.0 A3F:1 Type1 Inactive DFGin 7.0905 13.2083 BLAminus -126.1, 157.67 76.9, 82.69 -86.05, 21.36 306.23, 175.03 -61.66, -24.97 in-out in 8.3313 Saltbr-out 4.1956 HRD-in -82.54, -58.57 79.29, -1.49 out-in-out SNCoio in-out ActLoopNT-in 2.9128 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -103.22, 162.67 APE9-dihe-na -69.88, 165.81 APE8-dihe-in -53.93, 121.99 APE8-rot-in 312.82 APE67-dihe-in -59.42, -28.32 -57.34, -37.41 APE12-dist-in 10.6706 APE11-dist-out 6.476 APE10-dist-out 9.4819 APE9-dist-in 4.0726 Q207D None None XRAY 2.15 0.185 0.244 A 301.0 296.0 0 32 32 0 [[207, 497]] 1.0 3mtf Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 3MTFB Q04771 202 499 509.0 A3F:501 Type1 Inactive DFGin 7.5781 13.3226 BLAminus -114.45, 160.06 82.35, 87.49 -104.83, 25.86 291.12, 164.81 -75.29, -13.54 in-out in 8.5 Saltbr-out 4.2324 HRD-in -82.5, -60.12 85.3, -4.39 out-in-out SNCoio in-out ActLoopNT-in 2.869 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -111.75, 153.3 APE9-dihe-na -57.45, 170.81 APE8-dihe-in -65.39, 131.64 APE8-rot-in 306.28 APE67-dihe-in -49.77, -35.33 -68.1, -43.23 APE12-dist-in 10.6109 APE11-dist-out 6.4527 APE10-dist-out 9.3963 APE9-dist-in 4.1192 Q207D None None XRAY 2.15 0.185 0.244 B 301.0 298.0 0 32 32 0 [[207, 497]] 1.0 3mtf Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6EIXA Q04771 192 503 509.0 A3F:601 Type1 Inactive DFGin 7.3048 13.3822 BLAminus -122.31, 163.89 74.01, 85.68 -98.53, 23.31 310.02, 174.96 -66.89, -23.04 in-out in 9.0828 Saltbr-out 5.1598 HRD-in -81.6, -53.66 78.97, -2.54 out-in-out SNCoio in-out ActLoopNT-in 3.0232 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -113.45, 165.41 APE9-dihe-na -59.94, 163.8 APE8-dihe-in -59.76, 126.51 APE8-rot-in 307.55 APE67-dihe-in -58.05, -30.26 -58.58, -41.78 APE12-dist-in 10.589 APE11-dist-out 6.415 APE10-dist-out 9.3108 APE9-dist-in 3.8713 Q207E None None XRAY 2.3 0.191 0.249 A 340.0 312.0 0 32 32 0 [[207, 497]] 1.0 6eix Homo sapiens TKL_ACVR1_HUMAN TKL 2.9e-85 292.0 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: A3F

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name