Ligand: A1LVQ

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 3 100.0% 8XLQA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR1 FGFR1_HUMAN 8XLOA P11362 462 764 822.0 A1LVQ:60801 Type1.5_Back Inactive DFGin 5.3499 13.4604 BLAplus -120.07, 167.95 56.19, 37.83 -98.04, 4.56 56.68, 90.6 -112.93, 25.35 in-in in 7.9829 Saltbr-in 3.258 HRD-out -75.5, 142.74 -82.57, -37.38 in-out-out SNCioo out-out ActLoopNT-out 7.2004 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -113.57, 158.46 APE9-dihe-in -97.47, 110.21 APE8-dihe-out -58.39, -18.54 APE8-rot-na 19.21 APE67-dihe-in -81.65, 0.42 -62.39, -18.82 APE12-dist-na 20.741 APE11-dist-na 21.9456 APE10-dist-na 20.2119 APE9-dist-out 11.7779 C584S None None XRAY 2.36 0.21 0.255 A 310.0 293.0 10 30 30 0 [[478, 756]] 1.0 8xlo TYR_FGFR1_HUMAN TYR 2.1e-104 354.4 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8XLOB P11362 458 763 822.0 A1LVQ:60801 Type1.5_Back Inactive DFGin 5.5876 13.1874 BLAplus -122.66, 168.69 59.17, 27.93 -79.17, -12.14 48.47, 88.63 -115.21, 3.75 in-in in 7.7683 Saltbr-in 2.8826 HRD-out -89.09, 129.19 -58.3, -36.38 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -104.09, 159.35 APE9-dihe-in -98.63, 108.84 APE8-dihe-out -54.34, -25.08 APE8-rot-na 331.75 APE67-dihe-in -70.85, 2.53 -59.01, -24.97 APE12-dist-na 19.448 APE11-dist-na 20.7383 APE10-dist-na 19.2996 APE9-dist-out 11.7119 C584S None None XRAY 2.36 0.21 0.255 B 310.0 287.0 19 30 24 6 [[478, 756]] 1.0 8xlo TYR_FGFR1_HUMAN TYR 2.1e-104 354.4 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR4 FGFR4_HUMAN 8XLQA P22455 453 751 802.0 A1LVQ:801 Type1.5_Back Inactive DFGin 5.4641 13.0254 BLAplus -110.49, 154.34 56.41, 53.19 -87.86, -15.94 35.15, 87.75 -151.42, 999.0 in-in in 7.6576 Saltbr-in 3.2542 HRD-in -77.24, -55.4 78.04, -11.91 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -79.75, 139.57 APE9-dihe-in -110.17, 94.87 APE8-dihe-out -60.19, -19.05 APE8-rot-na 334.14 APE67-dihe-in -73.66, -3.29 -59.9, -24.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 11.8209 R664E None None XRAY 1.95 0.171 0.211 A 311.0 296.0 3 30 27 3 [[467, 745]] 1.0 8xlq TYR_FGFR4_HUMAN TYR 1.9e-100 341.4 1.0 261.0 261.0 629 630 631 633 635 503 520 524 609 611 610 612.0 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4

Ligand: A1LVQ

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 3 100.0% 8XLQA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR1 FGFR1_HUMAN 8XLOA P11362 462 764 822.0 A1LVQ:60801 Type1.5_Back Inactive DFGin 5.3499 13.4604 BLAplus -120.07, 167.95 56.19, 37.83 -98.04, 4.56 56.68, 90.6 -112.93, 25.35 in-in in 7.9829 Saltbr-in 3.258 HRD-out -75.5, 142.74 -82.57, -37.38 in-out-out SNCioo out-out ActLoopNT-out 7.2004 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -113.57, 158.46 APE9-dihe-in -97.47, 110.21 APE8-dihe-out -58.39, -18.54 APE8-rot-na 19.21 APE67-dihe-in -81.65, 0.42 -62.39, -18.82 APE12-dist-na 20.741 APE11-dist-na 21.9456 APE10-dist-na 20.2119 APE9-dist-out 11.7779 C584S None None XRAY 2.36 0.21 0.255 A 310.0 293.0 10 30 30 0 [[478, 756]] 1.0 8xlo Homo sapiens TYR_FGFR1_HUMAN TYR 2.1e-104 354.4 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 8XLOB P11362 458 763 822.0 A1LVQ:60801 Type1.5_Back Inactive DFGin 5.5876 13.1874 BLAplus -122.66, 168.69 59.17, 27.93 -79.17, -12.14 48.47, 88.63 -115.21, 3.75 in-in in 7.7683 Saltbr-in 2.8826 HRD-out -89.09, 129.19 -58.3, -36.38 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -104.09, 159.35 APE9-dihe-in -98.63, 108.84 APE8-dihe-out -54.34, -25.08 APE8-rot-na 331.75 APE67-dihe-in -70.85, 2.53 -59.01, -24.97 APE12-dist-na 19.448 APE11-dist-na 20.7383 APE10-dist-na 19.2996 APE9-dist-out 11.7119 C584S None None XRAY 2.36 0.21 0.255 B 310.0 287.0 19 30 24 6 [[478, 756]] 1.0 8xlo Homo sapiens TYR_FGFR1_HUMAN TYR 2.1e-104 354.4 1.0 260.0 260.0 640 641 642 644 646 514 531 535 620 622 621 623.0 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR4 FGFR4_HUMAN 8XLQA P22455 453 751 802.0 A1LVQ:801 Type1.5_Back Inactive DFGin 5.4641 13.0254 BLAplus -110.49, 154.34 56.41, 53.19 -87.86, -15.94 35.15, 87.75 -151.42, 999.0 in-in in 7.6576 Saltbr-in 3.2542 HRD-in -77.24, -55.4 78.04, -11.91 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -79.75, 139.57 APE9-dihe-in -110.17, 94.87 APE8-dihe-out -60.19, -19.05 APE8-rot-na 334.14 APE67-dihe-in -73.66, -3.29 -59.9, -24.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 11.8209 R664E None None XRAY 1.95 0.171 0.211 A 311.0 296.0 3 30 27 3 [[467, 745]] 1.0 8xlq Homo sapiens TYR_FGFR4_HUMAN TYR 1.9e-100 341.4 1.0 261.0 261.0 629 630 631 633 635 503 520 524 609 611 610 612.0 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4

Ligand: A1LVQ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name