Ligand: A1L8T

Total number of chains: 4
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 9U8CA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 9U8CA P00533 696 989 1210.0 A1L8T:61101 Type1 Inactive DFGin 5.1385 14.2244 BLAminus -152.72, -166.88 55.62, 62.26 -74.1, 21.88 305.31, 73.74 -53.06, -42.51 in-out in 8.537 Saltbr-out 3.6584 HRD-in -112.78, -28.58 64.39, -55.61 out-in-out SNCoio in-out ActLoopNT-in 3.3084 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 63.95, 52.79 APE9-dihe-in -131.72, 146.15 APE8-dihe-in -83.5, 103.66 APE8-rot-na 25.73 APE67-dihe-in -64.45, -43.78 -72.16, -36.45 APE12-dist-na 12.3682 APE11-dist-na 11.0603 APE10-dist-na 8.3941 APE9-dist-in 7.9626 None None None XRAY 3.5 0.275 0.3 A 338.0 292.0 2 30 30 0 [[712, 970]] 1.0 9u8c TYR_EGFR_HUMAN TYR 1.7e-85 292.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CB P00533 696 986 1210.0 A1L8T:61101 Type1 Active DFGin 5.7136 14.3834 BLAminus -153.52, -165.36 55.2, 60.65 -75.31, 21.07 288.54, 57.13 -53.37, -43.45 in-in in 8.8474 Saltbr-in 3.157 HRD-in -114.61, -29.69 63.56, -60.39 in-in-in SNCiii in-in ActLoopNT-in 3.3251 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.43, 125.24 APE9-dihe-in -148.34, 150.87 APE8-dihe-in -80.56, 88.11 APE8-rot-na 26.92 APE67-dihe-in -64.66, -40.79 -71.91, -41.96 APE12-dist-na 8.5866 APE11-dist-na 11.0253 APE10-dist-na 9.9144 APE9-dist-in 7.5864 None None None XRAY 3.5 0.275 0.3 B 338.0 288.0 3 30 30 0 [[712, 970]] 1.0 9u8c TYR_EGFR_HUMAN TYR 1.7e-85 292.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CC P00533 696 980 1210.0 A1L8T:61101 Type1 Inactive DFGin 5.2504 14.6552 BLAminus -150.18, -166.33 56.37, 62.15 -74.03, 19.4 282.34, 71.74 -55.17, -41.51 in-out in 8.2224 Saltbr-out 4.1573 HRD-in -113.86, -26.91 64.43, -58.55 out-in-in SNCoii in-in ActLoopNT-in 3.2996 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.57, 94.53 APE9-dihe-in -139.46, 143.63 APE8-dihe-in -83.28, 104.5 APE8-rot-na 28.04 APE67-dihe-in -65.21, -41.71 -68.24, -37.37 APE12-dist-na 8.6643 APE11-dist-na 10.7751 APE10-dist-na 8.4293 APE9-dist-in 7.2763 None None None XRAY 3.5 0.275 0.3 C 338.0 281.0 4 30 30 0 [[712, 970]] 1.0 9u8c TYR_EGFR_HUMAN TYR 1.7e-85 292.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CD P00533 696 987 1210.0 A1L8T:61101 Type1 None DFGin 5.5177 14.8417 BLAminus -152.89, -164.88 57.37, 59.02 -76.65, 17.66 286.7, 98.09 -55.38, -41.88 in-in in 8.8711 Saltbr-in 3.1866 HRD-in -114.09, -29.54 63.53, -55.66 in-in-none SNCiin in-none ActLoopNT-in 3.4616 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 146.4 APE8-dihe-in -82.7, 101.15 APE8-rot-na 29.1 APE67-dihe-in -63.15, -43.97 -69.62, -36.39 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.518 None None None XRAY 3.5 0.275 0.3 D 338.0 285.0 7 30 26 4 [[712, 970]] 1.0 9u8c TYR_EGFR_HUMAN TYR 1.7e-85 292.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: A1L8T

Total number of chains: 4
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 9U8CA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 9U8CA P00533 696 989 1210.0 A1L8T:61101 Type1 Inactive DFGin 5.1385 14.2244 BLAminus -152.72, -166.88 55.62, 62.26 -74.1, 21.88 305.31, 73.74 -53.06, -42.51 in-out in 8.537 Saltbr-out 3.6584 HRD-in -112.78, -28.58 64.39, -55.61 out-in-out SNCoio in-out ActLoopNT-in 3.3084 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 63.95, 52.79 APE9-dihe-in -131.72, 146.15 APE8-dihe-in -83.5, 103.66 APE8-rot-na 25.73 APE67-dihe-in -64.45, -43.78 -72.16, -36.45 APE12-dist-na 12.3682 APE11-dist-na 11.0603 APE10-dist-na 8.3941 APE9-dist-in 7.9626 None None None XRAY 3.5 0.275 0.3 A 338.0 292.0 2 30 30 0 [[712, 970]] 1.0 9u8c Homo sapiens TYR_EGFR_HUMAN TYR 1.7e-85 292.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CB P00533 696 986 1210.0 A1L8T:61101 Type1 Active DFGin 5.7136 14.3834 BLAminus -153.52, -165.36 55.2, 60.65 -75.31, 21.07 288.54, 57.13 -53.37, -43.45 in-in in 8.8474 Saltbr-in 3.157 HRD-in -114.61, -29.69 63.56, -60.39 in-in-in SNCiii in-in ActLoopNT-in 3.3251 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.43, 125.24 APE9-dihe-in -148.34, 150.87 APE8-dihe-in -80.56, 88.11 APE8-rot-na 26.92 APE67-dihe-in -64.66, -40.79 -71.91, -41.96 APE12-dist-na 8.5866 APE11-dist-na 11.0253 APE10-dist-na 9.9144 APE9-dist-in 7.5864 None None None XRAY 3.5 0.275 0.3 B 338.0 288.0 3 30 30 0 [[712, 970]] 1.0 9u8c Homo sapiens TYR_EGFR_HUMAN TYR 1.7e-85 292.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CC P00533 696 980 1210.0 A1L8T:61101 Type1 Inactive DFGin 5.2504 14.6552 BLAminus -150.18, -166.33 56.37, 62.15 -74.03, 19.4 282.34, 71.74 -55.17, -41.51 in-out in 8.2224 Saltbr-out 4.1573 HRD-in -113.86, -26.91 64.43, -58.55 out-in-in SNCoii in-in ActLoopNT-in 3.2996 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.57, 94.53 APE9-dihe-in -139.46, 143.63 APE8-dihe-in -83.28, 104.5 APE8-rot-na 28.04 APE67-dihe-in -65.21, -41.71 -68.24, -37.37 APE12-dist-na 8.6643 APE11-dist-na 10.7751 APE10-dist-na 8.4293 APE9-dist-in 7.2763 None None None XRAY 3.5 0.275 0.3 C 338.0 281.0 4 30 30 0 [[712, 970]] 1.0 9u8c Homo sapiens TYR_EGFR_HUMAN TYR 1.7e-85 292.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CD P00533 696 987 1210.0 A1L8T:61101 Type1 None DFGin 5.5177 14.8417 BLAminus -152.89, -164.88 57.37, 59.02 -76.65, 17.66 286.7, 98.09 -55.38, -41.88 in-in in 8.8711 Saltbr-in 3.1866 HRD-in -114.09, -29.54 63.53, -55.66 in-in-none SNCiin in-none ActLoopNT-in 3.4616 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 146.4 APE8-dihe-in -82.7, 101.15 APE8-rot-na 29.1 APE67-dihe-in -63.15, -43.97 -69.62, -36.39 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.518 None None None XRAY 3.5 0.275 0.3 D 338.0 285.0 7 30 26 4 [[712, 970]] 1.0 9u8c Homo sapiens TYR_EGFR_HUMAN TYR 1.7e-85 292.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: A1L8T

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name