Ligand: A1L8T

Total number of chains: 4
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 9U8CA
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 9U8CA P00533 696 989 1210.0 A1L8T:61101 Type1 Inactive DFGin 5.138 14.224 BLAminus -152.72, -166.88 55.62, 62.26 -74.1, 21.88 305.31, 73.74 -53.06, -42.51 in-out in 8.537 Saltbr-out 3.658 HRD-in -112.78, -28.58 64.39, -55.61 out-in-out SNCoio in-out ActLoopNT-in 3.308 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 63.95, 52.79 APE9-dihe-in -131.72, 146.15 APE8-dihe-in -83.5, 103.66 APE8-rot-na 25.73 APE67-dihe-in -64.45, -43.78 -72.16, -36.45 APE12-dist-na 12.368 APE11-dist-na 11.06 APE10-dist-na 8.394 APE9-dist-in 7.963 None None None XRAY 3.5 0.275 0.3 A 338 292 2 0 0 0 [[712, 970]] 1.0 9u8c TYR_EGFR_HUMAN TYR 1.7e-85 292.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CB P00533 696 986 1210.0 A1L8T:61101 Type1 Active DFGin 5.714 14.383 BLAminus -153.52, -165.36 55.2, 60.65 -75.31, 21.07 288.54, 57.13 -53.37, -43.45 in-in in 8.847 Saltbr-in 3.157 HRD-in -114.61, -29.69 63.56, -60.39 in-in-in SNCiii in-in ActLoopNT-in 3.325 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.43, 125.24 APE9-dihe-in -148.34, 150.87 APE8-dihe-in -80.56, 88.11 APE8-rot-na 26.92 APE67-dihe-in -64.66, -40.79 -71.91, -41.96 APE12-dist-na 8.587 APE11-dist-na 11.025 APE10-dist-na 9.914 APE9-dist-in 7.586 None None None XRAY 3.5 0.275 0.3 B 338 288 3 0 0 0 [[712, 970]] 1.0 9u8c TYR_EGFR_HUMAN TYR 1.7e-85 292.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CC P00533 696 980 1210.0 A1L8T:61101 Type1 Inactive DFGin 5.25 14.655 BLAminus -150.18, -166.33 56.37, 62.15 -74.03, 19.4 282.34, 71.74 -55.17, -41.51 in-out in 8.222 Saltbr-out 4.157 HRD-in -113.86, -26.91 64.43, -58.55 out-in-in SNCoii in-in ActLoopNT-in 3.3 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.57, 94.53 APE9-dihe-in -139.46, 143.63 APE8-dihe-in -83.28, 104.5 APE8-rot-na 28.04 APE67-dihe-in -65.21, -41.71 -68.24, -37.37 APE12-dist-na 8.664 APE11-dist-na 10.775 APE10-dist-na 8.429 APE9-dist-in 7.276 None None None XRAY 3.5 0.275 0.3 C 338 281 4 0 0 0 [[712, 970]] 1.0 9u8c TYR_EGFR_HUMAN TYR 1.7e-85 292.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CD P00533 696 987 1210.0 A1L8T:61101 Type1 None DFGin 5.518 14.842 BLAminus -152.89, -164.88 57.37, 59.02 -76.65, 17.66 286.7, 98.09 -55.38, -41.88 in-in in 8.871 Saltbr-in 3.187 HRD-in -114.09, -29.54 63.53, -55.66 in-in-none SNCiin in-none ActLoopNT-in 3.462 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 146.4 APE8-dihe-in -82.7, 101.15 APE8-rot-na 29.1 APE67-dihe-in -63.15, -43.97 -69.62, -36.39 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.518 None None None XRAY 3.5 0.275 0.3 D 338 285 7 0 0 4 [[712, 970]] 1.0 9u8c TYR_EGFR_HUMAN TYR 1.7e-85 292.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: A1L8T

Total number of chains: 4
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 9U8CA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 9U8CA P00533 696 989 1210.0 A1L8T:61101 Type1 Inactive DFGin 5.138 14.224 BLAminus -152.72, -166.88 55.62, 62.26 -74.1, 21.88 305.31, 73.74 -53.06, -42.51 in-out in 8.537 Saltbr-out 3.658 HRD-in -112.78, -28.58 64.39, -55.61 out-in-out SNCoio in-out ActLoopNT-in 3.308 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 63.95, 52.79 APE9-dihe-in -131.72, 146.15 APE8-dihe-in -83.5, 103.66 APE8-rot-na 25.73 APE67-dihe-in -64.45, -43.78 -72.16, -36.45 APE12-dist-na 12.368 APE11-dist-na 11.06 APE10-dist-na 8.394 APE9-dist-in 7.963 None None None XRAY 3.5 0.275 0.3 A 338 292 2 0 0 0 [[712, 970]] 1.0 9u8c Homo sapiens TYR_EGFR_HUMAN TYR 1.7e-85 292.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CB P00533 696 986 1210.0 A1L8T:61101 Type1 Active DFGin 5.714 14.383 BLAminus -153.52, -165.36 55.2, 60.65 -75.31, 21.07 288.54, 57.13 -53.37, -43.45 in-in in 8.847 Saltbr-in 3.157 HRD-in -114.61, -29.69 63.56, -60.39 in-in-in SNCiii in-in ActLoopNT-in 3.325 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.43, 125.24 APE9-dihe-in -148.34, 150.87 APE8-dihe-in -80.56, 88.11 APE8-rot-na 26.92 APE67-dihe-in -64.66, -40.79 -71.91, -41.96 APE12-dist-na 8.587 APE11-dist-na 11.025 APE10-dist-na 9.914 APE9-dist-in 7.586 None None None XRAY 3.5 0.275 0.3 B 338 288 3 0 0 0 [[712, 970]] 1.0 9u8c Homo sapiens TYR_EGFR_HUMAN TYR 1.7e-85 292.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CC P00533 696 980 1210.0 A1L8T:61101 Type1 Inactive DFGin 5.25 14.655 BLAminus -150.18, -166.33 56.37, 62.15 -74.03, 19.4 282.34, 71.74 -55.17, -41.51 in-out in 8.222 Saltbr-out 4.157 HRD-in -113.86, -26.91 64.43, -58.55 out-in-in SNCoii in-in ActLoopNT-in 3.3 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.57, 94.53 APE9-dihe-in -139.46, 143.63 APE8-dihe-in -83.28, 104.5 APE8-rot-na 28.04 APE67-dihe-in -65.21, -41.71 -68.24, -37.37 APE12-dist-na 8.664 APE11-dist-na 10.775 APE10-dist-na 8.429 APE9-dist-in 7.276 None None None XRAY 3.5 0.275 0.3 C 338 281 4 0 0 0 [[712, 970]] 1.0 9u8c Homo sapiens TYR_EGFR_HUMAN TYR 1.7e-85 292.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9U8CD P00533 696 987 1210.0 A1L8T:61101 Type1 None DFGin 5.518 14.842 BLAminus -152.89, -164.88 57.37, 59.02 -76.65, 17.66 286.7, 98.09 -55.38, -41.88 in-in in 8.871 Saltbr-in 3.187 HRD-in -114.09, -29.54 63.53, -55.66 in-in-none SNCiin in-none ActLoopNT-in 3.462 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 146.4 APE8-dihe-in -82.7, 101.15 APE8-rot-na 29.1 APE67-dihe-in -63.15, -43.97 -69.62, -36.39 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.518 None None None XRAY 3.5 0.275 0.3 D 338 285 7 0 0 4 [[712, 970]] 1.0 9u8c Homo sapiens TYR_EGFR_HUMAN TYR 1.7e-85 292.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: A1L8T

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name