Ligand: A1JDR

Total number of chains: 4
Active chains: 4
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 9R9JC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 9R9JA Q9NWZ3 161 458 460.0 A1JDR:501 Type1 Active DFGin 6.8659 14.3463 BLAminus -129.25, 179.93 58.23, 81.1 -101.74, 30.63 308.21, 100.29 -70.86, -33.46 in-in in 8.2604 Saltbr-in 2.7897 HRD-in -63.31, -48.65 74.54, -3.02 in-in-in SNCiii in-in ActLoopNT-in 2.7549 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.24, 156.68 APE9-dihe-na 136.68, -172.42 APE8-dihe-in -113.58, 112.35 APE8-rot-in 310.23 APE67-dihe-in -62.74, -18.52 -46.74, -43.52 APE12-dist-in 10.2203 APE11-dist-in 11.4894 APE10-dist-in 5.9896 APE9-dist-in 3.6231 None TPO345,SEP346 TPO345,SEP346 XRAY 2.39 0.223 0.263 A 308.0 286.0 12 30 26 4 [[183, 456]] 1.0 9r9j TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9JB Q9NWZ3 161 458 460.0 A1JDR:501 Type1 Active DFGin 6.8465 14.6405 BLAminus -131.61, -178.04 51.54, 84.54 -96.41, 15.7 297.09, 102.18 -62.93, -32.93 in-in in 8.5012 Saltbr-in 2.6937 HRD-in -63.37, -52.47 76.18, 0.48 in-in-in SNCiii in-in ActLoopNT-in 2.8344 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.52, 156.28 APE9-dihe-na 136.33, -173.58 APE8-dihe-in -113.86, 111.72 APE8-rot-in 311.39 APE67-dihe-in -61.96, -19.34 -42.6, -47.27 APE12-dist-in 10.2039 APE11-dist-in 11.5149 APE10-dist-in 6.0235 APE9-dist-in 3.5595 None TPO345,SEP346 TPO345,SEP346 XRAY 2.39 0.223 0.263 B 308.0 288.0 10 30 26 4 [[183, 456]] 1.0 9r9j TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9JC Q9NWZ3 164 458 460.0 A1JDR:501 Type1 Active DFGin 7.0778 14.5939 BLAminus -129.42, 175.26 60.25, 82.4 -97.97, 19.86 302.57, 101.34 -61.97, -34.27 in-in in 8.4059 Saltbr-in 2.7486 HRD-in -64.97, -49.19 74.55, -3.37 in-in-in SNCiii in-in ActLoopNT-in 2.8463 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.64, 156.94 APE9-dihe-na 136.07, -170.81 APE8-dihe-in -114.95, 112.8 APE8-rot-in 308.93 APE67-dihe-in -61.09, -18.92 -46.93, -44.09 APE12-dist-in 10.1321 APE11-dist-in 11.497 APE10-dist-in 6.0134 APE9-dist-in 3.654 None TPO345,SEP346 TPO345,SEP346 XRAY 2.39 0.223 0.263 C 308.0 286.0 9 30 26 4 [[183, 456]] 1.0 9r9j TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9JD Q9NWZ3 164 458 460.0 A1JDR:501 Type1 Active DFGin 6.7491 14.2965 BLAminus -130.45, 174.51 61.25, 83.64 -101.39, 23.57 312.6, 100.72 -63.42, -32.89 in-in in 8.4166 Saltbr-in 2.754 HRD-in -65.01, -48.51 74.63, -4.34 in-in-in SNCiii in-in ActLoopNT-in 2.7552 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -123.48, 154.74 APE9-dihe-na 136.0, -172.13 APE8-dihe-in -115.41, 112.47 APE8-rot-in 309.74 APE67-dihe-in -62.04, -18.44 -44.31, -45.7 APE12-dist-in 10.3119 APE11-dist-in 11.6086 APE10-dist-in 6.0691 APE9-dist-in 3.6424 None TPO345,SEP346 TPO345,SEP346 XRAY 2.39 0.223 0.263 D 308.0 281.0 14 30 25 5 [[183, 456]] 1.0 9r9j TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

Ligand: A1JDR

Total number of chains: 4
Active chains: 4
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 9R9JC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 9R9JA Q9NWZ3 161 458 460.0 A1JDR:501 Type1 Active DFGin 6.8659 14.3463 BLAminus -129.25, 179.93 58.23, 81.1 -101.74, 30.63 308.21, 100.29 -70.86, -33.46 in-in in 8.2604 Saltbr-in 2.7897 HRD-in -63.31, -48.65 74.54, -3.02 in-in-in SNCiii in-in ActLoopNT-in 2.7549 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.24, 156.68 APE9-dihe-na 136.68, -172.42 APE8-dihe-in -113.58, 112.35 APE8-rot-in 310.23 APE67-dihe-in -62.74, -18.52 -46.74, -43.52 APE12-dist-in 10.2203 APE11-dist-in 11.4894 APE10-dist-in 5.9896 APE9-dist-in 3.6231 None TPO345,SEP346 TPO345,SEP346 XRAY 2.39 0.223 0.263 A 308.0 286.0 12 30 26 4 [[183, 456]] 1.0 9r9j Homo sapiens TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9JB Q9NWZ3 161 458 460.0 A1JDR:501 Type1 Active DFGin 6.8465 14.6405 BLAminus -131.61, -178.04 51.54, 84.54 -96.41, 15.7 297.09, 102.18 -62.93, -32.93 in-in in 8.5012 Saltbr-in 2.6937 HRD-in -63.37, -52.47 76.18, 0.48 in-in-in SNCiii in-in ActLoopNT-in 2.8344 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.52, 156.28 APE9-dihe-na 136.33, -173.58 APE8-dihe-in -113.86, 111.72 APE8-rot-in 311.39 APE67-dihe-in -61.96, -19.34 -42.6, -47.27 APE12-dist-in 10.2039 APE11-dist-in 11.5149 APE10-dist-in 6.0235 APE9-dist-in 3.5595 None TPO345,SEP346 TPO345,SEP346 XRAY 2.39 0.223 0.263 B 308.0 288.0 10 30 26 4 [[183, 456]] 1.0 9r9j Homo sapiens TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9JC Q9NWZ3 164 458 460.0 A1JDR:501 Type1 Active DFGin 7.0778 14.5939 BLAminus -129.42, 175.26 60.25, 82.4 -97.97, 19.86 302.57, 101.34 -61.97, -34.27 in-in in 8.4059 Saltbr-in 2.7486 HRD-in -64.97, -49.19 74.55, -3.37 in-in-in SNCiii in-in ActLoopNT-in 2.8463 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.64, 156.94 APE9-dihe-na 136.07, -170.81 APE8-dihe-in -114.95, 112.8 APE8-rot-in 308.93 APE67-dihe-in -61.09, -18.92 -46.93, -44.09 APE12-dist-in 10.1321 APE11-dist-in 11.497 APE10-dist-in 6.0134 APE9-dist-in 3.654 None TPO345,SEP346 TPO345,SEP346 XRAY 2.39 0.223 0.263 C 308.0 286.0 9 30 26 4 [[183, 456]] 1.0 9r9j Homo sapiens TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 9R9JD Q9NWZ3 164 458 460.0 A1JDR:501 Type1 Active DFGin 6.7491 14.2965 BLAminus -130.45, 174.51 61.25, 83.64 -101.39, 23.57 312.6, 100.72 -63.42, -32.89 in-in in 8.4166 Saltbr-in 2.754 HRD-in -65.01, -48.51 74.63, -4.34 in-in-in SNCiii in-in ActLoopNT-in 2.7552 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -123.48, 154.74 APE9-dihe-na 136.0, -172.13 APE8-dihe-in -115.41, 112.47 APE8-rot-in 309.74 APE67-dihe-in -62.04, -18.44 -44.31, -45.7 APE12-dist-in 10.3119 APE11-dist-in 11.6086 APE10-dist-in 6.0691 APE9-dist-in 3.6424 None TPO345,SEP346 TPO345,SEP346 XRAY 2.39 0.223 0.263 D 308.0 281.0 14 30 25 5 [[183, 456]] 1.0 9r9j Homo sapiens TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

Ligand: A1JDR

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name