Ligand: A1D8H

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8ZMLB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE TNIK TNIK_HUMAN 8ZMLB Q9UKE5 10 310 1360.0 A1D8H:401 Type1 Active DFGin 6.341 14.6812 BLAminus -137.68, 170.11 66.37, 91.63 -101.51, 26.8 289.02, 87.32 -60.41, -41.21 in-in in 9.0887 Saltbr-in 2.7085 HRD-in -65.54, -56.99 83.62, -6.79 in-in-in SNCiii in-in ActLoopNT-in 2.9119 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.62, 146.65 APE9-dihe-na 135.32, -165.11 APE8-dihe-in -104.54, 114.88 APE8-rot-in 314.82 APE67-dihe-in -65.12, -32.28 -36.82, -49.34 APE12-dist-in 8.5912 APE11-dist-in 11.5357 APE10-dist-in 5.8051 APE9-dist-in 3.5974 None TPO181,TPO187 TPO181,TPO187 XRAY 2.489 0.259 0.326 B 303.0 300.0 0 28 28 0 [[25, 289]] 1.0 8zml STE_TNIK_HUMAN STE 2.9e-105 357.2 1.0 257.0 257.0 170 171 172 174 176 54 69 73 150 152 151 153.0 215 198 193 192 191 190 189 188 187 106 TRAF2 and NCK-interacting protein kinase
STE TNIK TNIK_HUMAN 8ZMLA Q9UKE5 11 312 1360.0 A1D8H:401 Type1.5_Back Active DFGin 6.4739 14.5645 BLAminus -139.61, 165.9 70.83, 90.89 -103.46, 28.11 290.64, 88.46 -72.56, -24.37 in-in in 8.975 Saltbr-in 2.7052 HRD-in -67.56, -52.68 74.08, 10.21 in-in-in SNCiii in-in ActLoopNT-in 2.8997 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.53, 157.64 APE9-dihe-na 122.71, -174.5 APE8-dihe-in -96.82, 116.31 APE8-rot-in 313.0 APE67-dihe-in -60.49, -29.81 -40.39, -49.28 APE12-dist-in 8.4145 APE11-dist-in 11.5964 APE10-dist-in 5.8435 APE9-dist-in 3.373 None TPO181,TPO187 TPO181,TPO187 XRAY 2.489 0.259 0.326 A 303.0 301.0 0 28 28 0 [[25, 289]] 1.0 8zml STE_TNIK_HUMAN STE 2.9e-105 357.2 1.0 257.0 257.0 170 171 172 174 176 54 69 73 150 152 151 153.0 215 198 193 192 191 190 189 188 187 106 TRAF2 and NCK-interacting protein kinase

Ligand: A1D8H

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8ZMLB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE TNIK TNIK_HUMAN 8ZMLB Q9UKE5 10 310 1360.0 A1D8H:401 Type1 Active DFGin 6.341 14.6812 BLAminus -137.68, 170.11 66.37, 91.63 -101.51, 26.8 289.02, 87.32 -60.41, -41.21 in-in in 9.0887 Saltbr-in 2.7085 HRD-in -65.54, -56.99 83.62, -6.79 in-in-in SNCiii in-in ActLoopNT-in 2.9119 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.62, 146.65 APE9-dihe-na 135.32, -165.11 APE8-dihe-in -104.54, 114.88 APE8-rot-in 314.82 APE67-dihe-in -65.12, -32.28 -36.82, -49.34 APE12-dist-in 8.5912 APE11-dist-in 11.5357 APE10-dist-in 5.8051 APE9-dist-in 3.5974 None TPO181,TPO187 TPO181,TPO187 XRAY 2.489 0.259 0.326 B 303.0 300.0 0 28 28 0 [[25, 289]] 1.0 8zml Homo sapiens STE_TNIK_HUMAN STE 2.9e-105 357.2 1.0 257.0 257.0 170 171 172 174 176 54 69 73 150 152 151 153.0 215 198 193 192 191 190 189 188 187 106 TRAF2 and NCK-interacting protein kinase
STE TNIK TNIK_HUMAN 8ZMLA Q9UKE5 11 312 1360.0 A1D8H:401 Type1.5_Back Active DFGin 6.4739 14.5645 BLAminus -139.61, 165.9 70.83, 90.89 -103.46, 28.11 290.64, 88.46 -72.56, -24.37 in-in in 8.975 Saltbr-in 2.7052 HRD-in -67.56, -52.68 74.08, 10.21 in-in-in SNCiii in-in ActLoopNT-in 2.8997 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.53, 157.64 APE9-dihe-na 122.71, -174.5 APE8-dihe-in -96.82, 116.31 APE8-rot-in 313.0 APE67-dihe-in -60.49, -29.81 -40.39, -49.28 APE12-dist-in 8.4145 APE11-dist-in 11.5964 APE10-dist-in 5.8435 APE9-dist-in 3.373 None TPO181,TPO187 TPO181,TPO187 XRAY 2.489 0.259 0.326 A 303.0 301.0 0 28 28 0 [[25, 289]] 1.0 8zml Homo sapiens STE_TNIK_HUMAN STE 2.9e-105 357.2 1.0 257.0 257.0 170 171 172 174 176 54 69 73 150 152 151 153.0 215 198 193 192 191 190 189 188 187 106 TRAF2 and NCK-interacting protein kinase

Ligand: A1D8H

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name