Ligand: A1AFR

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 100.0% 8W2XA
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 8W2XA P21802 458 765 821.0 A1AFR:60801 Type1.5_Back Inactive DFGin 5.186 13.347 BLAplus -120.4, 170.08 47.84, 47.71 -101.14, -15.65 62.51, 79.97 -87.59, -18.95 in-in in 8.011 Saltbr-in 2.948 HRD-in -69.21, -58.65 84.1, -5.97 in-out-out SNCioo out-out ActLoopNT-out 8.558 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -78.12, 147.0 APE9-dihe-in -116.78, 92.64 APE8-dihe-out -53.69, -17.45 APE8-rot-na 330.1 APE67-dihe-in -71.44, -10.68 -63.08, -26.44 APE12-dist-na 19.353 APE11-dist-na 21.562 APE10-dist-na 17.572 APE9-dist-out 11.588 None None None XRAY 2.98 0.211 0.237 A 324 304 4 0 0 0 [[481, 759]] 1.0 8w2x TYR_FGFR2_HUMAN TYR 6.2e-104 352.8 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W2XB P21802 458 765 821.0 A1AFR:60801 Type1.5_Back Inactive DFGin 5.172 13.672 BLAplus -120.88, 172.87 46.97, 47.43 -101.96, -10.72 62.07, 80.77 -85.12, -16.26 in-in in 8.256 Saltbr-in 3.578 HRD-in -69.81, -58.19 83.73, -4.52 in-out-out SNCioo out-out ActLoopNT-out 7.566 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -81.55, 151.04 APE9-dihe-in -117.66, 89.73 APE8-dihe-out -57.08, -16.9 APE8-rot-na 336.97 APE67-dihe-in -70.95, -11.38 -63.76, -26.5 APE12-dist-na 19.294 APE11-dist-na 21.709 APE10-dist-na 18.148 APE9-dist-out 11.385 None None None XRAY 2.98 0.211 0.237 B 324 291 17 0 0 3 [[481, 759]] 1.0 8w2x TYR_FGFR2_HUMAN TYR 6.2e-104 352.8 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

Ligand: A1AFR

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 2 100.0% 8W2XA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 8W2XA P21802 458 765 821.0 A1AFR:60801 Type1.5_Back Inactive DFGin 5.186 13.347 BLAplus -120.4, 170.08 47.84, 47.71 -101.14, -15.65 62.51, 79.97 -87.59, -18.95 in-in in 8.011 Saltbr-in 2.948 HRD-in -69.21, -58.65 84.1, -5.97 in-out-out SNCioo out-out ActLoopNT-out 8.558 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -78.12, 147.0 APE9-dihe-in -116.78, 92.64 APE8-dihe-out -53.69, -17.45 APE8-rot-na 330.1 APE67-dihe-in -71.44, -10.68 -63.08, -26.44 APE12-dist-na 19.353 APE11-dist-na 21.562 APE10-dist-na 17.572 APE9-dist-out 11.588 None None None XRAY 2.98 0.211 0.237 A 324 304 4 0 0 0 [[481, 759]] 1.0 8w2x Homo sapiens TYR_FGFR2_HUMAN TYR 6.2e-104 352.8 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W2XB P21802 458 765 821.0 A1AFR:60801 Type1.5_Back Inactive DFGin 5.172 13.672 BLAplus -120.88, 172.87 46.97, 47.43 -101.96, -10.72 62.07, 80.77 -85.12, -16.26 in-in in 8.256 Saltbr-in 3.578 HRD-in -69.81, -58.19 83.73, -4.52 in-out-out SNCioo out-out ActLoopNT-out 7.566 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -81.55, 151.04 APE9-dihe-in -117.66, 89.73 APE8-dihe-out -57.08, -16.9 APE8-rot-na 336.97 APE67-dihe-in -70.95, -11.38 -63.76, -26.5 APE12-dist-na 19.294 APE11-dist-na 21.709 APE10-dist-na 18.148 APE9-dist-out 11.385 None None None XRAY 2.98 0.211 0.237 B 324 291 17 0 0 3 [[481, 759]] 1.0 8w2x Homo sapiens TYR_FGFR2_HUMAN TYR 6.2e-104 352.8 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

Ligand: A1AFR

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name