Ligand: A1A29

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9D8EA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 9D8EA Q04771 193 499 509.0 A1A29:703 Type1 Inactive DFGin 7.3824 13.3292 BLAminus -126.65, 164.15 70.79, 84.87 -98.58, 18.71 305.74, 179.57 -69.37, -18.79 in-out in 9.1301 Saltbr-out 4.9779 HRD-in -75.96, -48.11 74.25, -2.76 out-in-in SNCoii in-in ActLoopNT-in 2.8721 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.78, -21.58 APE9-dihe-na -90.92, -141.42 APE8-dihe-in -99.59, 122.26 APE8-rot-in 299.69 APE67-dihe-in -58.11, -27.93 -57.36, -41.17 APE12-dist-in 11.7286 APE11-dist-in 12.2513 APE10-dist-in 6.291 APE9-dist-in 3.8351 None None None XRAY 1.72 0.192 0.215 A 330.0 307.0 0 32 32 0 [[207, 497]] 1.0 9d8e TKL_ACVR1_HUMAN TKL 2.6e-85 292.1 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 9D8EB Q04771 193 498 509.0 A1A29:501 Type1 Inactive DFGin 7.4881 13.211 BLAminus -125.78, 165.64 71.99, 85.49 -102.71, 20.66 303.4, 179.67 -73.83, -20.49 in-out in 8.9223 Saltbr-out 4.969 HRD-in -75.14, -48.46 72.82, -0.2 out-in-in SNCoii in-in ActLoopNT-in 2.8076 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.27, -24.55 APE9-dihe-na -80.6, -148.51 APE8-dihe-in -94.26, 124.81 APE8-rot-in 298.35 APE67-dihe-in -52.79, -30.62 -58.26, -44.61 APE12-dist-in 12.4238 APE11-dist-in 12.3785 APE10-dist-in 6.4077 APE9-dist-in 3.8232 None None None XRAY 1.72 0.192 0.215 B 330.0 306.0 0 32 32 0 [[207, 497]] 1.0 9d8e TKL_ACVR1_HUMAN TKL 2.6e-85 292.1 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: A1A29

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9D8EA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 9D8EA Q04771 193 499 509.0 A1A29:703 Type1 Inactive DFGin 7.3824 13.3292 BLAminus -126.65, 164.15 70.79, 84.87 -98.58, 18.71 305.74, 179.57 -69.37, -18.79 in-out in 9.1301 Saltbr-out 4.9779 HRD-in -75.96, -48.11 74.25, -2.76 out-in-in SNCoii in-in ActLoopNT-in 2.8721 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.78, -21.58 APE9-dihe-na -90.92, -141.42 APE8-dihe-in -99.59, 122.26 APE8-rot-in 299.69 APE67-dihe-in -58.11, -27.93 -57.36, -41.17 APE12-dist-in 11.7286 APE11-dist-in 12.2513 APE10-dist-in 6.291 APE9-dist-in 3.8351 None None None XRAY 1.72 0.192 0.215 A 330.0 307.0 0 32 32 0 [[207, 497]] 1.0 9d8e Homo sapiens TKL_ACVR1_HUMAN TKL 2.6e-85 292.1 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 9D8EB Q04771 193 498 509.0 A1A29:501 Type1 Inactive DFGin 7.4881 13.211 BLAminus -125.78, 165.64 71.99, 85.49 -102.71, 20.66 303.4, 179.67 -73.83, -20.49 in-out in 8.9223 Saltbr-out 4.969 HRD-in -75.14, -48.46 72.82, -0.2 out-in-in SNCoii in-in ActLoopNT-in 2.8076 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.27, -24.55 APE9-dihe-na -80.6, -148.51 APE8-dihe-in -94.26, 124.81 APE8-rot-in 298.35 APE67-dihe-in -52.79, -30.62 -58.26, -44.61 APE12-dist-in 12.4238 APE11-dist-in 12.3785 APE10-dist-in 6.4077 APE9-dist-in 3.8232 None None None XRAY 1.72 0.192 0.215 B 330.0 306.0 0 32 32 0 [[207, 497]] 1.0 9d8e Homo sapiens TKL_ACVR1_HUMAN TKL 2.6e-85 292.1 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: A1A29

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name