Ligand: 9TO

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6ACRA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 6ACRA Q04771 203 498 509.0 9TO:501 Type1 Inactive DFGin 7.1534 13.1095 BLAminus -124.89, 170.02 71.35, 87.97 -99.79, 21.94 299.39, 166.61 -70.31, -13.55 in-out in 8.3372 Saltbr-out 4.0133 HRD-in -84.47, -53.43 78.41, -0.38 out-in-out SNCoio in-out ActLoopNT-in 2.8987 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -116.18, 166.2 APE9-dihe-na -63.37, 165.5 APE8-dihe-in -62.27, 124.69 APE8-rot-in 304.34 APE67-dihe-in -61.96, -28.37 -60.94, -34.65 APE12-dist-in 10.548 APE11-dist-out 6.5246 APE10-dist-out 9.133 APE9-dist-in 3.9847 R206H None None XRAY 2.01 0.215 0.257 A 301.0 294.0 2 32 32 0 [[207, 497]] 1.0 6acr TKL_ACVR1_HUMAN TKL 1.8e-85 292.7 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6ACRB Q04771 203 498 509.0 9TO:501 Type1 Inactive DFGin 7.3777 13.1203 BLAminus -127.75, 173.06 71.61, 79.74 -95.63, 20.34 301.12, 177.54 -68.09, -20.68 in-out in 8.5461 Saltbr-out 4.317 HRD-in -78.48, -57.97 79.82, 2.93 out-in-out SNCoio in-out ActLoopNT-in 2.7905 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -124.88, 159.1 APE9-dihe-na -64.17, 165.67 APE8-dihe-in -58.46, 129.98 APE8-rot-in 315.31 APE67-dihe-in -57.05, -29.95 -67.86, -34.69 APE12-dist-in 10.5303 APE11-dist-out 6.3727 APE10-dist-out 8.8759 APE9-dist-in 4.0153 R206H None None XRAY 2.01 0.215 0.257 B 301.0 293.0 3 32 32 0 [[207, 497]] 1.0 6acr TKL_ACVR1_HUMAN TKL 1.8e-85 292.7 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: 9TO

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6ACRA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 6ACRA Q04771 203 498 509.0 9TO:501 Type1 Inactive DFGin 7.1534 13.1095 BLAminus -124.89, 170.02 71.35, 87.97 -99.79, 21.94 299.39, 166.61 -70.31, -13.55 in-out in 8.3372 Saltbr-out 4.0133 HRD-in -84.47, -53.43 78.41, -0.38 out-in-out SNCoio in-out ActLoopNT-in 2.8987 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -116.18, 166.2 APE9-dihe-na -63.37, 165.5 APE8-dihe-in -62.27, 124.69 APE8-rot-in 304.34 APE67-dihe-in -61.96, -28.37 -60.94, -34.65 APE12-dist-in 10.548 APE11-dist-out 6.5246 APE10-dist-out 9.133 APE9-dist-in 3.9847 R206H None None XRAY 2.01 0.215 0.257 A 301.0 294.0 2 32 32 0 [[207, 497]] 1.0 6acr Homo sapiens TKL_ACVR1_HUMAN TKL 1.8e-85 292.7 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 6ACRB Q04771 203 498 509.0 9TO:501 Type1 Inactive DFGin 7.3777 13.1203 BLAminus -127.75, 173.06 71.61, 79.74 -95.63, 20.34 301.12, 177.54 -68.09, -20.68 in-out in 8.5461 Saltbr-out 4.317 HRD-in -78.48, -57.97 79.82, 2.93 out-in-out SNCoio in-out ActLoopNT-in 2.7905 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -124.88, 159.1 APE9-dihe-na -64.17, 165.67 APE8-dihe-in -58.46, 129.98 APE8-rot-in 315.31 APE67-dihe-in -57.05, -29.95 -67.86, -34.69 APE12-dist-in 10.5303 APE11-dist-out 6.3727 APE10-dist-out 8.8759 APE9-dist-in 4.0153 R206H None None XRAY 2.01 0.215 0.257 B 301.0 293.0 3 32 32 0 [[207, 497]] 1.0 6acr Homo sapiens TKL_ACVR1_HUMAN TKL 1.8e-85 292.7 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

Ligand: 9TO

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name