Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | EGFR | EGFR_HUMAN | 6P1LA | P00533 | 701 | 1007 | 1210.0 | ANP:1102,9LL:1103 | ATPlike,Type3 | Inactive | DFGin | 5.09 | 14.609 | BLBplus | -137.99, 174.26 | 51.86, 38.49 | -97.68, 160.33 | 56.12, 79.32 | 80.95, 13.49 | out-out | out | 13.09 | Saltbr-out | 11.075 | HRD-in | -66.81, -53.87 | 69.64, 3.15 | out-none-out | SNCono | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 129.91 | APE8-dihe-in | -92.34, 76.37 | APE8-rot-na | 35.99 | APE67-dihe-in | -76.25, -4.78 | -68.05, -35.38 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.361 | T790M,V948R | None | None | XRAY | 2.8 | 0.203 | 0.237 | A | 327 | 288 | 19 | 0 | 0 | 17 | [[712, 970]] | 1.0 | 6p1l | TYR_EGFR_HUMAN | TYR | 6e-88 | 300.6 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 6P1LC | P00533 | 702 | 1005 | 1210.0 | ANP:1102,9LL:1103 | ATPlike,Type3 | Inactive | DFGin | 4.947 | 14.346 | BLBplus | -138.12, 175.57 | 52.19, 39.44 | -97.35, 162.11 | 56.76, 79.57 | 81.63, 13.51 | out-out | out | 13.069 | Saltbr-out | 12.69 | HRD-in | -65.46, -53.47 | 68.76, 3.35 | out-none-out | SNCono | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, -21.1 | APE8-dihe-in | -91.14, 76.85 | APE8-rot-na | 36.16 | APE67-dihe-in | -74.42, -4.16 | -69.53, -34.23 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 9.035 | T790M,V948R | None | None | XRAY | 2.8 | 0.203 | 0.237 | C | 327 | 280 | 24 | 0 | 0 | 17 | [[712, 970]] | 1.0 | 6p1l | TYR_EGFR_HUMAN | TYR | 6e-88 | 300.6 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 6P1LD | P00533 | 702 | 1015 | 1210.0 | ANP:1102,9LL:1103 | ATPlike,Type3 | Inactive | DFGin | 5.193 | 14.634 | BLBplus | -136.45, 175.46 | 51.75, 39.49 | -96.95, 158.96 | 56.24, 81.53 | 81.72, 11.0 | out-out | out | 13.155 | Saltbr-out | 10.982 | HRD-in | -66.43, -53.42 | 65.79, 5.44 | out-none-out | SNCono | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 129.86 | APE8-dihe-in | -92.75, 77.55 | APE8-rot-na | 35.81 | APE67-dihe-in | -75.19, -4.23 | -67.58, -35.18 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.094 | T790M,V948R | None | None | XRAY | 2.8 | 0.203 | 0.237 | D | 327 | 296 | 17 | 0 | 0 | 17 | [[712, 970]] | 1.0 | 6p1l | TYR_EGFR_HUMAN | TYR | 6e-88 | 300.6 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXMD | P00533 | 700 | 1007 | 1210.0 | ANP:1101,9LL:1103 | ATPlike,Type3 | Inactive | DFGin | 4.952 | 14.337 | BLBplus | -135.28, 170.25 | 61.86, 31.57 | -85.27, 155.14 | 53.77, 85.22 | 78.23, 19.31 | out-out | out | 13.049 | Saltbr-out | 11.894 | HRD-in | -66.52, -63.02 | 84.71, -6.37 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 136.04 | APE8-dihe-in | -80.42, 66.88 | APE8-rot-na | 32.97 | APE67-dihe-in | -76.05, -3.45 | -51.47, -42.13 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.762 | T790M,V948R | None | None | XRAY | 2.192 | 0.228 | 0.271 | D | 331 | 291 | 17 | 0 | 0 | 17 | [[712, 970]] | 1.0 | 7jxm | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXMB | P00533 | 701 | 1012 | 1210.0 | YY3:1101,9LL:1102 | Type1,Type3 | Inactive | DFGin | 5.155 | 14.648 | BLBplus | -133.95, 169.04 | 59.67, 39.65 | -96.16, 166.65 | 49.37, 86.58 | 68.24, 16.57 | out-out | out | 13.166 | Saltbr-out | 10.454 | HRD-in | -67.1, -62.37 | 83.6, -7.78 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 126.13 | APE8-dihe-in | -90.39, 74.47 | APE8-rot-na | 39.92 | APE67-dihe-in | -71.29, -11.25 | -51.45, -39.54 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.779 | T790M,V948R | None | None | XRAY | 2.192 | 0.228 | 0.271 | B | 331 | 296 | 16 | 0 | 0 | 16 | [[712, 970]] | 1.0 | 7jxm | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 6Z4BA | P00533 | 700 | 982 | 1210.0 | Q6K:1101,9LL:1102 | Type1,Type3 | Inactive | DFGin | 5.693 | 14.816 | BLBplus | -133.89, 164.94 | 59.43, 51.96 | -98.19, 144.81 | 41.57, 85.88 | 67.58, 19.62 | out-none | out | 14.398 | Saltbr-none | 999.0 | HRD-in | -67.89, -64.09 | 87.77, -27.23 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 7.141 | ActLoopCT-out | TYR | APEdihe_niiai | APEdist_aaao | APE10-dihe-none | 999.0, -2.64 | APE9-dihe-in | -120.02, 130.13 | APE8-dihe-in | -80.9, 78.34 | APE8-rot-na | 31.39 | APE67-dihe-in | -73.81, -4.61 | -60.28, -41.17 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 12.71 | APE9-dist-out | 8.134 | T790M,V948R | None | None | XRAY | 2.5 | 0.222 | 0.251 | A | 333 | 271 | 12 | 0 | 0 | 12 | [[712, 970]] | 1.0 | 6z4b | TYR_EGFR_HUMAN | TYR | 6.4e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 6Z4BB | P00533 | 699 | 984 | 1210.0 | Q6K:1101,9LL:1102 | Type1,Type3 | Inactive | DFGin | 6.233 | 14.529 | BLBplus | -131.04, 166.01 | 60.41, 49.56 | -101.97, 145.48 | 42.99, 86.21 | -89.28, 999.0 | out-out | out | 12.903 | Saltbr-out | 9.732 | HRD-out | -138.19, 95.22 | -83.97, -17.5 | out-none-out | SNCono | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 123.87 | APE8-dihe-in | -88.45, 76.4 | APE8-rot-na | 32.2 | APE67-dihe-in | -72.84, -5.09 | -59.16, -39.52 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 9.257 | T790M,V948R | None | None | XRAY | 2.5 | 0.222 | 0.251 | B | 333 | 263 | 23 | 0 | 0 | 18 | [[712, 970]] | 1.0 | 6z4b | TYR_EGFR_HUMAN | TYR | 6.4e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 5ZWJA | P00533 | 702 | 985 | 1210.0 | 9LL:1101 | Type3 | Inactive | DFGin | 5.542 | 14.462 | BLBplus | -134.76, 169.78 | 70.33, 21.35 | -80.26, 157.71 | 46.02, 86.11 | 85.63, 6.58 | out-none | out | 12.365 | Saltbr-none | 999.0 | HRD-in | -62.57, -46.38 | 74.18, -0.41 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 170.69 | APE8-dihe-in | -84.81, 75.57 | APE8-rot-na | 34.77 | APE67-dihe-in | -62.54, -42.94 | -62.02, -41.38 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.058 | T790M,C797S,V948R | None | None | XRAY | 2.9 | 0.256 | 0.272 | A | 355 | 267 | 17 | 0 | 0 | 17 | [[712, 970]] | 1.0 | 5zwj | TYR_EGFR_HUMAN | TYR | 5.9e-88 | 300.6 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | EGFR | EGFR_HUMAN | 6P1LA | P00533 | 701 | 1007 | 1210.0 | ANP:1102,9LL:1103 | ATPlike,Type3 | Inactive | DFGin | 5.09 | 14.609 | BLBplus | -137.99, 174.26 | 51.86, 38.49 | -97.68, 160.33 | 56.12, 79.32 | 80.95, 13.49 | out-out | out | 13.09 | Saltbr-out | 11.075 | HRD-in | -66.81, -53.87 | 69.64, 3.15 | out-none-out | SNCono | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 129.91 | APE8-dihe-in | -92.34, 76.37 | APE8-rot-na | 35.99 | APE67-dihe-in | -76.25, -4.78 | -68.05, -35.38 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.361 | T790M,V948R | None | None | XRAY | 2.8 | 0.203 | 0.237 | A | 327 | 288 | 19 | 0 | 0 | 17 | [[712, 970]] | 1.0 | 6p1l | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6e-88 | 300.6 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 6P1LC | P00533 | 702 | 1005 | 1210.0 | ANP:1102,9LL:1103 | ATPlike,Type3 | Inactive | DFGin | 4.947 | 14.346 | BLBplus | -138.12, 175.57 | 52.19, 39.44 | -97.35, 162.11 | 56.76, 79.57 | 81.63, 13.51 | out-out | out | 13.069 | Saltbr-out | 12.69 | HRD-in | -65.46, -53.47 | 68.76, 3.35 | out-none-out | SNCono | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, -21.1 | APE8-dihe-in | -91.14, 76.85 | APE8-rot-na | 36.16 | APE67-dihe-in | -74.42, -4.16 | -69.53, -34.23 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 9.035 | T790M,V948R | None | None | XRAY | 2.8 | 0.203 | 0.237 | C | 327 | 280 | 24 | 0 | 0 | 17 | [[712, 970]] | 1.0 | 6p1l | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6e-88 | 300.6 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 6P1LD | P00533 | 702 | 1015 | 1210.0 | ANP:1102,9LL:1103 | ATPlike,Type3 | Inactive | DFGin | 5.193 | 14.634 | BLBplus | -136.45, 175.46 | 51.75, 39.49 | -96.95, 158.96 | 56.24, 81.53 | 81.72, 11.0 | out-out | out | 13.155 | Saltbr-out | 10.982 | HRD-in | -66.43, -53.42 | 65.79, 5.44 | out-none-out | SNCono | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 129.86 | APE8-dihe-in | -92.75, 77.55 | APE8-rot-na | 35.81 | APE67-dihe-in | -75.19, -4.23 | -67.58, -35.18 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.094 | T790M,V948R | None | None | XRAY | 2.8 | 0.203 | 0.237 | D | 327 | 296 | 17 | 0 | 0 | 17 | [[712, 970]] | 1.0 | 6p1l | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6e-88 | 300.6 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXMD | P00533 | 700 | 1007 | 1210.0 | ANP:1101,9LL:1103 | ATPlike,Type3 | Inactive | DFGin | 4.952 | 14.337 | BLBplus | -135.28, 170.25 | 61.86, 31.57 | -85.27, 155.14 | 53.77, 85.22 | 78.23, 19.31 | out-out | out | 13.049 | Saltbr-out | 11.894 | HRD-in | -66.52, -63.02 | 84.71, -6.37 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 136.04 | APE8-dihe-in | -80.42, 66.88 | APE8-rot-na | 32.97 | APE67-dihe-in | -76.05, -3.45 | -51.47, -42.13 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.762 | T790M,V948R | None | None | XRAY | 2.192 | 0.228 | 0.271 | D | 331 | 291 | 17 | 0 | 0 | 17 | [[712, 970]] | 1.0 | 7jxm | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXMB | P00533 | 701 | 1012 | 1210.0 | YY3:1101,9LL:1102 | Type1,Type3 | Inactive | DFGin | 5.155 | 14.648 | BLBplus | -133.95, 169.04 | 59.67, 39.65 | -96.16, 166.65 | 49.37, 86.58 | 68.24, 16.57 | out-out | out | 13.166 | Saltbr-out | 10.454 | HRD-in | -67.1, -62.37 | 83.6, -7.78 | out-none-none | SNConn | none-none | ActLoopNT-none | 999.0 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 126.13 | APE8-dihe-in | -90.39, 74.47 | APE8-rot-na | 39.92 | APE67-dihe-in | -71.29, -11.25 | -51.45, -39.54 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 7.779 | T790M,V948R | None | None | XRAY | 2.192 | 0.228 | 0.271 | B | 331 | 296 | 16 | 0 | 0 | 16 | [[712, 970]] | 1.0 | 7jxm | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6.3e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 6Z4BA | P00533 | 700 | 982 | 1210.0 | Q6K:1101,9LL:1102 | Type1,Type3 | Inactive | DFGin | 5.693 | 14.816 | BLBplus | -133.89, 164.94 | 59.43, 51.96 | -98.19, 144.81 | 41.57, 85.88 | 67.58, 19.62 | out-none | out | 14.398 | Saltbr-none | 999.0 | HRD-in | -67.89, -64.09 | 87.77, -27.23 | none-out-out | SNCnoo | out-out | ActLoopNT-out | 7.141 | ActLoopCT-out | TYR | APEdihe_niiai | APEdist_aaao | APE10-dihe-none | 999.0, -2.64 | APE9-dihe-in | -120.02, 130.13 | APE8-dihe-in | -80.9, 78.34 | APE8-rot-na | 31.39 | APE67-dihe-in | -73.81, -4.61 | -60.28, -41.17 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 12.71 | APE9-dist-out | 8.134 | T790M,V948R | None | None | XRAY | 2.5 | 0.222 | 0.251 | A | 333 | 271 | 12 | 0 | 0 | 12 | [[712, 970]] | 1.0 | 6z4b | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6.4e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 6Z4BB | P00533 | 699 | 984 | 1210.0 | Q6K:1101,9LL:1102 | Type1,Type3 | Inactive | DFGin | 6.233 | 14.529 | BLBplus | -131.04, 166.01 | 60.41, 49.56 | -101.97, 145.48 | 42.99, 86.21 | -89.28, 999.0 | out-out | out | 12.903 | Saltbr-out | 9.732 | HRD-out | -138.19, 95.22 | -83.97, -17.5 | out-none-out | SNCono | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 123.87 | APE8-dihe-in | -88.45, 76.4 | APE8-rot-na | 32.2 | APE67-dihe-in | -72.84, -5.09 | -59.16, -39.52 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 9.257 | T790M,V948R | None | None | XRAY | 2.5 | 0.222 | 0.251 | B | 333 | 263 | 23 | 0 | 0 | 18 | [[712, 970]] | 1.0 | 6z4b | Homo sapiens | TYR_EGFR_HUMAN | TYR | 6.4e-88 | 300.5 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 5ZWJA | P00533 | 702 | 985 | 1210.0 | 9LL:1101 | Type3 | Inactive | DFGin | 5.542 | 14.462 | BLBplus | -134.76, 169.78 | 70.33, 21.35 | -80.26, 157.71 | 46.02, 86.11 | 85.63, 6.58 | out-none | out | 12.365 | Saltbr-none | 999.0 | HRD-in | -62.57, -46.38 | 74.18, -0.41 | none-none-out | SNCnno | none-out | ActLoopNT-none | 999.0 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 170.69 | APE8-dihe-in | -84.81, 75.57 | APE8-rot-na | 34.77 | APE67-dihe-in | -62.54, -42.94 | -62.02, -41.38 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.058 | T790M,C797S,V948R | None | None | XRAY | 2.9 | 0.256 | 0.272 | A | 355 | 267 | 17 | 0 | 0 | 17 | [[712, 970]] | 1.0 | 5zwj | Homo sapiens | TYR_EGFR_HUMAN | TYR | 5.9e-88 | 300.6 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|