Ligand: 9IV

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 100.0% 7Q8YA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 TTBK1 TTBK1_HUMAN 7Q8VA Q5TCY1 21 312 1321.0 9IV:402 Type1 Inactive DFGin 4.956 12.4872 ABAminus -96.4, -34.81 -145.41, 147.15 -136.52, 21.39 310.35, 107.49 -68.54, -19.14 in-in in 6.8994 Saltbr-in 3.2476 HRD-in -76.22, -55.35 75.88, 0.13 in-in-in SNCiii in-in ActLoopNT-in 2.9352 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -123.07, -12.61 APE9-dihe-na -78.61, -166.5 APE8-dihe-in -86.61, 134.33 APE8-rot-in 307.3 APE67-dihe-in -56.23, -43.38 -59.6, -46.19 APE12-dist-in 11.9662 APE11-dist-in 10.9299 APE10-dist-in 6.5071 APE9-dist-in 4.0188 None None None XRAY 2.13 0.19 0.244 A 309.0 292.0 0 34 34 0 [[34, 295]] 1.0 7q8v CK1_TTBK1_HUMAN CK1 4.2e-105 356.8 1.0 262.0 262.0 175 176 177 179 181 63 77 81 151 153 152 154.0 221 209 204 203 202 201 200 199 198 108 Tau-tubulin kinase 1
CK1 TTBK2 TTBK2_HUMAN 7Q8YA Q6IQ55 6 299 1244.0 9IV:303 Type1 Inactive DFGin 5.001 12.7358 ABAminus -96.43, -23.37 -148.68, 147.6 -137.42, 20.4 309.85, 104.45 -57.76, -38.41 in-in in 6.5214 Saltbr-in 2.7297 HRD-in -82.35, -54.44 77.13, -1.28 in-in-in SNCiii in-in ActLoopNT-in 2.8314 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.88, 1.77 APE9-dihe-na -80.07, -153.46 APE8-dihe-in -102.62, 129.14 APE8-rot-in 288.61 APE67-dihe-in -59.7, -42.15 -59.82, -42.6 APE12-dist-in 11.462 APE11-dist-in 10.2001 APE10-dist-in 6.8104 APE9-dist-in 4.6242 None None None XRAY 1.6 0.179 0.205 A 300.0 294.0 0 34 34 0 [[21, 282]] 1.0 7q8y CK1_TTBK2_HUMAN CK1 7.8e-104 352.6 1.0 262.0 262.0 162 163 164 166 168 50 64 68 138 140 139 141.0 208 196 191 190 189 188 187 186 185 95 Tau-tubulin kinase 2
CK1 TTBK2 TTBK2_HUMAN 7Q8YB Q6IQ55 7 299 1244.0 9IV:303 Type1 Inactive DFGin 4.9351 12.9188 ABAminus -102.2, -23.11 -149.17, 143.47 -132.06, 19.74 312.12, 105.76 -58.08, -34.08 in-in in 6.5484 Saltbr-in 2.7075 HRD-in -76.93, -54.19 72.75, -0.27 in-in-in SNCiii in-in ActLoopNT-in 2.8566 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -120.41, 123.98 APE9-dihe-na 120.86, -146.42 APE8-dihe-in -111.89, 127.5 APE8-rot-in 302.95 APE67-dihe-in -58.34, -39.15 -55.33, -42.36 APE12-dist-in 11.6684 APE11-dist-in 11.7396 APE10-dist-in 6.2067 APE9-dist-in 3.8124 None None None XRAY 1.6 0.179 0.205 B 300.0 293.0 0 34 34 0 [[21, 282]] 1.0 7q8y CK1_TTBK2_HUMAN CK1 7.8e-104 352.6 1.0 262.0 262.0 162 163 164 166 168 50 64 68 138 140 139 141.0 208 196 191 190 189 188 187 186 185 95 Tau-tubulin kinase 2

Ligand: 9IV

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 100.0% 7Q8YA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 TTBK1 TTBK1_HUMAN 7Q8VA Q5TCY1 21 312 1321.0 9IV:402 Type1 Inactive DFGin 4.956 12.4872 ABAminus -96.4, -34.81 -145.41, 147.15 -136.52, 21.39 310.35, 107.49 -68.54, -19.14 in-in in 6.8994 Saltbr-in 3.2476 HRD-in -76.22, -55.35 75.88, 0.13 in-in-in SNCiii in-in ActLoopNT-in 2.9352 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -123.07, -12.61 APE9-dihe-na -78.61, -166.5 APE8-dihe-in -86.61, 134.33 APE8-rot-in 307.3 APE67-dihe-in -56.23, -43.38 -59.6, -46.19 APE12-dist-in 11.9662 APE11-dist-in 10.9299 APE10-dist-in 6.5071 APE9-dist-in 4.0188 None None None XRAY 2.13 0.19 0.244 A 309.0 292.0 0 34 34 0 [[34, 295]] 1.0 7q8v Homo sapiens CK1_TTBK1_HUMAN CK1 4.2e-105 356.8 1.0 262.0 262.0 175 176 177 179 181 63 77 81 151 153 152 154.0 221 209 204 203 202 201 200 199 198 108 Tau-tubulin kinase 1
CK1 TTBK2 TTBK2_HUMAN 7Q8YA Q6IQ55 6 299 1244.0 9IV:303 Type1 Inactive DFGin 5.001 12.7358 ABAminus -96.43, -23.37 -148.68, 147.6 -137.42, 20.4 309.85, 104.45 -57.76, -38.41 in-in in 6.5214 Saltbr-in 2.7297 HRD-in -82.35, -54.44 77.13, -1.28 in-in-in SNCiii in-in ActLoopNT-in 2.8314 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.88, 1.77 APE9-dihe-na -80.07, -153.46 APE8-dihe-in -102.62, 129.14 APE8-rot-in 288.61 APE67-dihe-in -59.7, -42.15 -59.82, -42.6 APE12-dist-in 11.462 APE11-dist-in 10.2001 APE10-dist-in 6.8104 APE9-dist-in 4.6242 None None None XRAY 1.6 0.179 0.205 A 300.0 294.0 0 34 34 0 [[21, 282]] 1.0 7q8y Homo sapiens CK1_TTBK2_HUMAN CK1 7.8e-104 352.6 1.0 262.0 262.0 162 163 164 166 168 50 64 68 138 140 139 141.0 208 196 191 190 189 188 187 186 185 95 Tau-tubulin kinase 2
CK1 TTBK2 TTBK2_HUMAN 7Q8YB Q6IQ55 7 299 1244.0 9IV:303 Type1 Inactive DFGin 4.9351 12.9188 ABAminus -102.2, -23.11 -149.17, 143.47 -132.06, 19.74 312.12, 105.76 -58.08, -34.08 in-in in 6.5484 Saltbr-in 2.7075 HRD-in -76.93, -54.19 72.75, -0.27 in-in-in SNCiii in-in ActLoopNT-in 2.8566 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -120.41, 123.98 APE9-dihe-na 120.86, -146.42 APE8-dihe-in -111.89, 127.5 APE8-rot-in 302.95 APE67-dihe-in -58.34, -39.15 -55.33, -42.36 APE12-dist-in 11.6684 APE11-dist-in 11.7396 APE10-dist-in 6.2067 APE9-dist-in 3.8124 None None None XRAY 1.6 0.179 0.205 B 300.0 293.0 0 34 34 0 [[21, 282]] 1.0 7q8y Homo sapiens CK1_TTBK2_HUMAN CK1 7.8e-104 352.6 1.0 262.0 262.0 162 163 164 166 168 50 64 68 138 140 139 141.0 208 196 191 190 189 188 187 186 185 95 Tau-tubulin kinase 2

Ligand: 9IV

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name