Ligand: 90F

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 3 100.0% 7WCTA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR4 FGFR4_HUMAN 7WCXA P22455 453 752 802.0 90F:801 Type1 Inactive DFGin 5.2632 13.1414 BLAplus -114.81, 160.0 54.39, 48.08 -89.68, -16.38 44.55, 83.39 -109.65, 26.27 in-in in 7.7923 Saltbr-in 2.5114 HRD-in -76.2, -43.73 72.01, -8.39 in-out-out SNCioo out-out ActLoopNT-out 8.6444 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -80.24, 137.24 APE9-dihe-in -109.54, 93.42 APE8-dihe-out -57.65, -19.77 APE8-rot-na 335.57 APE67-dihe-in -71.93, -5.42 -64.19, -25.82 APE12-dist-na 19.0736 APE11-dist-na 20.85 APE10-dist-na 16.8219 APE9-dist-out 11.9043 C477A,R664E None None XRAY 2.175 0.173 0.221 A 309.0 300.0 0 30 30 0 [[467, 745]] 1.0 7wcx TYR_FGFR4_HUMAN TYR 7e-101 342.8 1.0 261.0 261.0 629 630 631 633 635 503 520 524 609 611 610 612.0 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7WCWA P22455 453 752 802.0 90F:801 Type1 Inactive DFGin 5.8394 13.063 BLAplus -123.48, 161.59 54.95, 50.1 -96.76, -24.53 39.59, 83.16 -101.63, 31.89 in-in in 7.5817 Saltbr-in 3.4 HRD-in -77.43, -45.16 72.65, -7.54 in-out-out SNCioo out-out ActLoopNT-out 8.6329 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -81.49, 135.61 APE9-dihe-in -107.87, 94.77 APE8-dihe-out -59.45, -18.22 APE8-rot-na 336.81 APE67-dihe-in -74.15, -1.22 -67.3, -23.03 APE12-dist-na 19.4349 APE11-dist-na 20.9958 APE10-dist-na 16.9286 APE9-dist-out 11.8399 C477A,R664E None None XRAY 2.317 0.179 0.221 A 309.0 300.0 0 30 30 0 [[467, 745]] 1.0 7wcw TYR_FGFR4_HUMAN TYR 1.9e-100 341.4 1.0 261.0 261.0 629 630 631 633 635 503 520 524 609 611 610 612.0 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7WCTA P22455 453 752 802.0 90F:801 Type1 Inactive DFGin 5.4993 13.0077 BLAplus -115.75, 158.15 54.59, 44.67 -82.33, -22.35 42.51, 87.35 -106.03, 33.12 in-in in 7.4757 Saltbr-in 2.8808 HRD-in -76.31, -44.07 70.33, -3.05 in-out-out SNCioo out-out ActLoopNT-out 8.4968 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -84.18, 139.68 APE9-dihe-in -111.32, 93.14 APE8-dihe-out -55.09, -20.87 APE8-rot-na 333.3 APE67-dihe-in -74.74, -3.5 -65.15, -23.14 APE12-dist-na 19.4627 APE11-dist-na 21.0452 APE10-dist-na 17.0744 APE9-dist-out 11.7717 R664E None None XRAY 2.106 0.184 0.217 A 311.0 300.0 0 30 30 0 [[467, 745]] 1.0 7wct TYR_FGFR4_HUMAN TYR 1.9e-100 341.4 1.0 261.0 261.0 629 630 631 633 635 503 520 524 609 611 610 612.0 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4

Ligand: 90F

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 3 100.0% 7WCTA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR4 FGFR4_HUMAN 7WCXA P22455 453 752 802.0 90F:801 Type1 Inactive DFGin 5.2632 13.1414 BLAplus -114.81, 160.0 54.39, 48.08 -89.68, -16.38 44.55, 83.39 -109.65, 26.27 in-in in 7.7923 Saltbr-in 2.5114 HRD-in -76.2, -43.73 72.01, -8.39 in-out-out SNCioo out-out ActLoopNT-out 8.6444 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -80.24, 137.24 APE9-dihe-in -109.54, 93.42 APE8-dihe-out -57.65, -19.77 APE8-rot-na 335.57 APE67-dihe-in -71.93, -5.42 -64.19, -25.82 APE12-dist-na 19.0736 APE11-dist-na 20.85 APE10-dist-na 16.8219 APE9-dist-out 11.9043 C477A,R664E None None XRAY 2.175 0.173 0.221 A 309.0 300.0 0 30 30 0 [[467, 745]] 1.0 7wcx Homo sapiens TYR_FGFR4_HUMAN TYR 7e-101 342.8 1.0 261.0 261.0 629 630 631 633 635 503 520 524 609 611 610 612.0 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7WCWA P22455 453 752 802.0 90F:801 Type1 Inactive DFGin 5.8394 13.063 BLAplus -123.48, 161.59 54.95, 50.1 -96.76, -24.53 39.59, 83.16 -101.63, 31.89 in-in in 7.5817 Saltbr-in 3.4 HRD-in -77.43, -45.16 72.65, -7.54 in-out-out SNCioo out-out ActLoopNT-out 8.6329 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -81.49, 135.61 APE9-dihe-in -107.87, 94.77 APE8-dihe-out -59.45, -18.22 APE8-rot-na 336.81 APE67-dihe-in -74.15, -1.22 -67.3, -23.03 APE12-dist-na 19.4349 APE11-dist-na 20.9958 APE10-dist-na 16.9286 APE9-dist-out 11.8399 C477A,R664E None None XRAY 2.317 0.179 0.221 A 309.0 300.0 0 30 30 0 [[467, 745]] 1.0 7wcw Homo sapiens TYR_FGFR4_HUMAN TYR 1.9e-100 341.4 1.0 261.0 261.0 629 630 631 633 635 503 520 524 609 611 610 612.0 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 7WCTA P22455 453 752 802.0 90F:801 Type1 Inactive DFGin 5.4993 13.0077 BLAplus -115.75, 158.15 54.59, 44.67 -82.33, -22.35 42.51, 87.35 -106.03, 33.12 in-in in 7.4757 Saltbr-in 2.8808 HRD-in -76.31, -44.07 70.33, -3.05 in-out-out SNCioo out-out ActLoopNT-out 8.4968 ActLoopCT-out TYR APEdihe_iioai APEdist_aaao APE10-dihe-in -84.18, 139.68 APE9-dihe-in -111.32, 93.14 APE8-dihe-out -55.09, -20.87 APE8-rot-na 333.3 APE67-dihe-in -74.74, -3.5 -65.15, -23.14 APE12-dist-na 19.4627 APE11-dist-na 21.0452 APE10-dist-na 17.0744 APE9-dist-out 11.7717 R664E None None XRAY 2.106 0.184 0.217 A 311.0 300.0 0 30 30 0 [[467, 745]] 1.0 7wct Homo sapiens TYR_FGFR4_HUMAN TYR 1.9e-100 341.4 1.0 261.0 261.0 629 630 631 633 635 503 520 524 609 611 610 612.0 671 659 654 653 652 651 650 649 648 551 Fibroblast growth factor receptor 4

Ligand: 90F

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name