KinCore

Ligand: 8ET

Total number of chains: 1

Active chains: 1

Total number of genes: 1

Spatial label	Dihedral label	Number of Chains	Percent	Representative
DFGin	BLAminus	1	100.0%	5MZLA

Download database table as tsv Basic page

Hover over column headers for tooltip help

Group	Gene	SwissprotID	PDB	UniprotID	First_obs_res	Last_obs_res	Length_Unp	Ligand	Ligand_type	Activity_label	Spatial_label	Phe_Glu4_dis	Phe_Lys_dis	Dihedral_label	XDFG φ,ψ	DFG-Asp φ,ψ	DFG-Phe φ,ψ	DFG-Phe χ1,χ2	DFG-Gly φ,ψ	ChelixSaltbr_label	Chelix_label	Lys_Glu_dis	Saltbr_label	LysNZ_GluOE_dis	HRD_label	His φ,ψ	Arg φ,ψ	SNC_label	SNCpymol_label	ActLoop_label	ActLoopNT_label	DFG6_XHRD_dis	ActLoopCT_label	APEtype	APEdihe_label	APEdist_label	APE10_dihe_label	APE10 φ,ψ	APE9_dihe_label	APE9 φ,ψ	APE8_dihe_label	APE8 φ,ψ	APE8_rotamer_label	APE8 χ1	APE67_label	APE6 φ,ψ	APE7 φ,ψ	APE12_dist_label	APE12_DFG4_dis	APE11_dist_label	APE11_DFG4_dis	APE10_dist_label	APE10_DFG4_dis	APE9_dist_label	APE9_Arg_dis	Chain_mut	Chain_phos	Modified_aa	Method	Resolution	Rvalue	FreeRvalue	Chain_id	ChainLen	Ordered_residues	DomainBreak	ActLoopLength	ActLoopResolvedResidues	ActLoopDisorderedResidues	Kinase_domains_Unp	N_Kinase_domains_Unp	pdb	Kincore_name	hmm	Evalue	Score	hmmbeg	hmmend	hmmlen	XDFGnum	DFGnum	PHEnum	DFG4num	DFG6num	LYSnum	GLUnum	GLU4num	XHRDnum	ARGnum	HRDnum	HRDaspnum	aFaspnum	APEnum	APE6num	APE7num	APE8num	APE9num	APE10num	APE11num	APE12num	Hinge1num	Protein_name
CAMK	PIM1	PIM1_HUMAN	5MZLA	P11309	33	305	313.0	8ET:401	Type1	Active	DFGin	6.07	14.414	BLAminus	-131.62, 169.01	61.49, 83.12	-91.63, 17.39	285.49, 78.9	-67.71, -14.16	in-in	in	8.766	Saltbr-in	2.589	HRD-na-A	-71.92, -48.75	69.25, 10.18	in-in-in	SNCiii	in-in	ActLoopNT-in	2.799	ActLoopCT-in	nonTYR	APEdihe_aaiii	APEdist_iiii	APE10-dihe-na	-133.79, 22.06	APE9-dihe-na	-80.91, -155.94	APE8-dihe-in	-90.97, 120.03	APE8-rot-in	302.78	APE67-dihe-in	-70.3, -10.66	-61.44, -39.24	APE12-dist-in	9.734	APE11-dist-in	8.509	APE10-dist-in	5.304	APE9-dist-in	3.696	R250G	None	None	XRAY	1.955	0.158	0.183	A	313	269	4	0	0	0	[[38, 290]]	1.0	5mzl	CAMK_PIM1_HUMAN	CAMK	1.5e-64	223.7	1	256	256	185	186	187	189	191	67	89	93	164	166	165	167	224	211	206	205	204	203	202	201	200	121	Serine/threonine-protein kinase pim-1

Ligand: 8ET

Total number of chains: 2

Active chains: 1

Total number of genes: 2

Spatial label	Dihedral label	Number of Chains	Percent	Representative
DFGin	BLAminus	2	100.0%	5N1FA

Download database table as tsv Basic page

Hover over column headers for tooltip help

Group	Gene	SwissprotID	PDB	UniprotID	First_obs_res	Last_obs_res	Length_Unp	Ligand	Ligand_type	Activity_label	Spatial_label	Phe_Glu4_dis	Phe_Lys_dis	Dihedral_label	XDFG φ,ψ	DFG-Asp φ,ψ	DFG-Phe φ,ψ	DFG-Phe χ1,χ2	DFG-Gly φ,ψ	ChelixSaltbr_label	Chelix_label	Lys_Glu_dis	Saltbr_label	LysNZ_GluOE_dis	HRD_label	His φ,ψ	Arg φ,ψ	SNC_label	SNCpymol_label	ActLoop_label	ActLoopNT_label	DFG6_XHRD_dis	ActLoopCT_label	APEtype	APEdihe_label	APEdist_label	APE10_dihe_label	APE10 φ,ψ	APE9_dihe_label	APE9 φ,ψ	APE8_dihe_label	APE8 φ,ψ	APE8_rotamer_label	APE8 χ1	APE67_label	APE6 φ,ψ	APE7 φ,ψ	APE12_dist_label	APE12_DFG4_dis	APE11_dist_label	APE11_DFG4_dis	APE10_dist_label	APE10_DFG4_dis	APE9_dist_label	APE9_Arg_dis	Chain_mut	Chain_phos	Modified_aa	Method	Resolution	Rvalue	FreeRvalue	Chain_id	ChainLen	Ordered_residues	DomainBreak	ActLoopLength	ActLoopResolvedResidues	ActLoopDisorderedResidues	Kinase_domains_Unp	N_Kinase_domains_Unp	pdb	Species	Kincore_name	hmm	Evalue	Score	hmmbeg	hmmend	hmmlen	XDFGnum	DFGnum	PHEnum	DFG4num	DFG6num	LYSnum	GLUnum	GLU4num	XHRDnum	ARGnum	HRDnum	HRDaspnum	aFaspnum	APEnum	APE6num	APE7num	APE8num	APE9num	APE10num	APE11num	APE12num	Hinge1num	Protein_name
AGC	PRKACA	KAPCA_CRIGR	5N1FA	P25321	12	351	351.0	8ET:60403	Type1	Inactive	DFGin	6.278	14.42	BLAminus	-125.76, 161.54	76.66, 90.69	-99.25, 24.03	270.12, 55.91	-61.05, -26.16	in-in	in	8.612	Saltbr-in	2.812	HRD-in	-86.34, -52.94	70.41, 12.62	in-in-out	SNCiio	in-out	ActLoopNT-in	2.927	ActLoopCT-out	nonTYR	APEdihe_aaioi	APEdist_iiii	APE10-dihe-na	-158.69, 154.25	APE9-dihe-na	121.48, 156.96	APE8-dihe-in	-75.85, 143.28	APE8-rot-out	195.81	APE67-dihe-in	-63.37, -20.85	-47.21, -48.33	APE12-dist-in	8.052	APE11-dist-in	11.174	APE10-dist-in	5.701	APE9-dist-in	4.066	None	SEP11,SEP140,TPO198,SEP339	SEP11,SEP140,TPO198,SEP339	XRAY	1.12	0.138	0.156	A	353	340	0	0	0	0	[[44, 298]]	1.0	5n1f	Cricetulus griseus	AGC_PRKACA_CRIGR	AGC	6.6e-95	323.2	1	260	260	184	185	186	188	190	73	92	96	164	166	165	167	221	209	204	203	202	201	200	199	198	122	cAMP-dependent protein kinase catalytic subunit alpha
CAMK	PIM1	PIM1_HUMAN	5MZLA	P11309	33	305	313.0	8ET:401	Type1	Active	DFGin	6.07	14.414	BLAminus	-131.62, 169.01	61.49, 83.12	-91.63, 17.39	285.49, 78.9	-67.71, -14.16	in-in	in	8.766	Saltbr-in	2.589	HRD-na-A	-71.92, -48.75	69.25, 10.18	in-in-in	SNCiii	in-in	ActLoopNT-in	2.799	ActLoopCT-in	nonTYR	APEdihe_aaiii	APEdist_iiii	APE10-dihe-na	-133.79, 22.06	APE9-dihe-na	-80.91, -155.94	APE8-dihe-in	-90.97, 120.03	APE8-rot-in	302.78	APE67-dihe-in	-70.3, -10.66	-61.44, -39.24	APE12-dist-in	9.734	APE11-dist-in	8.509	APE10-dist-in	5.304	APE9-dist-in	3.696	R250G	None	None	XRAY	1.955	0.158	0.183	A	313	269	4	0	0	0	[[38, 290]]	1.0	5mzl	Homo sapiens	CAMK_PIM1_HUMAN	CAMK	1.5e-64	223.7	1	256	256	185	186	187	189	191	67	89	93	164	166	165	167	224	211	206	205	204	203	202	201	200	121	Serine/threonine-protein kinase pim-1

Ligand: 8ET

Total number of chains: 1

Active chains: 0

Total number of genes: 1

Spatial label	Dihedral label	Number of Chains	Percent	Representative
DFGin	BLAminus	1	100.0%	5N1FA

Download database table as tsv Basic page

Hover over column headers for tooltip help

Group	Gene	SwissprotID	PDB	UniprotID	First_obs_res	Last_obs_res	Length_Unp	Ligand	Ligand_type	Activity_label	Spatial_label	Phe_Glu4_dis	Phe_Lys_dis	Dihedral_label	XDFG φ,ψ	DFG-Asp φ,ψ	DFG-Phe φ,ψ	DFG-Phe χ1,χ2	DFG-Gly φ,ψ	ChelixSaltbr_label	Chelix_label	Lys_Glu_dis	Saltbr_label	LysNZ_GluOE_dis	HRD_label	His φ,ψ	Arg φ,ψ	SNC_label	SNCpymol_label	ActLoop_label	ActLoopNT_label	DFG6_XHRD_dis	ActLoopCT_label	APEtype	APEdihe_label	APEdist_label	APE10_dihe_label	APE10 φ,ψ	APE9_dihe_label	APE9 φ,ψ	APE8_dihe_label	APE8 φ,ψ	APE8_rotamer_label	APE8 χ1	APE67_label	APE6 φ,ψ	APE7 φ,ψ	APE12_dist_label	APE12_DFG4_dis	APE11_dist_label	APE11_DFG4_dis	APE10_dist_label	APE10_DFG4_dis	APE9_dist_label	APE9_Arg_dis	Chain_mut	Chain_phos	Modified_aa	Method	Resolution	Rvalue	FreeRvalue	Chain_id	ChainLen	Ordered_residues	DomainBreak	ActLoopLength	ActLoopResolvedResidues	ActLoopDisorderedResidues	Kinase_domains_Unp	N_Kinase_domains_Unp	pdb	Species	Kincore_name	hmm	Evalue	Score	hmmbeg	hmmend	hmmlen	XDFGnum	DFGnum	PHEnum	DFG4num	DFG6num	LYSnum	GLUnum	GLU4num	XHRDnum	ARGnum	HRDnum	HRDaspnum	aFaspnum	APEnum	APE6num	APE7num	APE8num	APE9num	APE10num	APE11num	APE12num	Hinge1num	Protein_name
AGC	PRKACA	KAPCA_CRIGR	5N1FA	P25321	12	351	351.0	8ET:60403	Type1	Inactive	DFGin	6.278	14.42	BLAminus	-125.76, 161.54	76.66, 90.69	-99.25, 24.03	270.12, 55.91	-61.05, -26.16	in-in	in	8.612	Saltbr-in	2.812	HRD-in	-86.34, -52.94	70.41, 12.62	in-in-out	SNCiio	in-out	ActLoopNT-in	2.927	ActLoopCT-out	nonTYR	APEdihe_aaioi	APEdist_iiii	APE10-dihe-na	-158.69, 154.25	APE9-dihe-na	121.48, 156.96	APE8-dihe-in	-75.85, 143.28	APE8-rot-out	195.81	APE67-dihe-in	-63.37, -20.85	-47.21, -48.33	APE12-dist-in	8.052	APE11-dist-in	11.174	APE10-dist-in	5.701	APE9-dist-in	4.066	None	SEP11,SEP140,TPO198,SEP339	SEP11,SEP140,TPO198,SEP339	XRAY	1.12	0.138	0.156	A	353	340	0	0	0	0	[[44, 298]]	1.0	5n1f	Cricetulus griseus	AGC_PRKACA_CRIGR	AGC	6.6e-95	323.2	1	260	260	184	185	186	188	190	73	92	96	164	166	165	167	221	209	204	203	202	201	200	199	198	122	cAMP-dependent protein kinase catalytic subunit alpha